Sero-survey of polio antibodies and quality of acute flaccid paralysis surveillance in Chongqing, China

The risk of polio importation and re-emergence persists since epidemic polio still occurs in some countries, and the resurgence of polio occurring almost 20 years after polio eradication was declared in Asia has been reported. We analyzed the results of acute flaccid paralysis (AFP) surveillance in Korea to assess the quality of AFP surveillance and understand the etiology of non-polio enterovirus (NPEV)-associated central nervous system diseases in a polio-free area. We investigated 637 AFP patients under 15 years of age whose cases were confirmed during 2012–2019 by virus isolation, real-time reverse transcription polymerase chain reaction, and VP1 gene sequencing. Among the 637 AFP cases, NPEV was detected in 213 (33.4%) patients, with the majority observed in EV-A71, with 54.9% of NPEV positives. EV-A71 has been shown to play a role as a major causative agent in most neurological diseases except for Guillain-Barré syndrome (GBS), acute disseminated encephalomyelitis (ADEM), and meningitis. This study provides information on the AFP surveillance situation in Korea and highlights the polio eradication stage in the monitoring and characterization of NPEV against the outbreak of neurological infectious diseases such as polio.

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Evaluation of Acute Flaccid Paralysis Surveillance System in Polio-Free Jordan, 2012

10.2196/preprints.10617.a ◽

2018 ◽

Author(s):

Fatima Zerriouh ◽

M Abdallat ◽

L Ghaffari ◽

I Iblan ◽

K Abusal ◽

...

Keyword(s):

Surveillance System ◽

Acute Flaccid Paralysis ◽

Flaccid Paralysis ◽

Acute Flaccid Paralysis Surveillance

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Detection of non-polio and polio enteroviruses in Acute Flaccid Paralysis surveillance in Turkey

Acta Microbiologica et Immunologica Hungarica ◽

10.1556/030.2021.01353 ◽

2021 ◽

Author(s):

Gulay Korukluoglu ◽

Umit Ozdemirer ◽

Fatma Bayrakdar ◽

Zehra Unal ◽

Yasemin Cosgun ◽

...

Keyword(s):

Acute Flaccid Paralysis ◽

Flaccid Paralysis ◽

Sequencing Analysis ◽

National Data ◽

Polio Virus ◽

Vaccination Rates ◽

Acute Flaccid Paralysis Surveillance ◽

Polio Vaccination ◽

Afp Surveillance ◽

Comprehensive Study

AbstractPoliomyelitis was a disease feared worldwide, striking suddenly and paralysing mainly children for life. Monitoring of suspected cases of poliomyelitis is carried out with Acute Flaccid Paralysis (AFP) surveillance in Turkey. This study examines national data of AFP surveillance and the epidemiology of enteroviruses (EV) in Turkey from 2000 to 2019 and gives an overview of the detected serotypes of EVs. A total of 13,640 samples collected from patients with 5216 AFP pre-diagnosed cases (2 samples from each patient) and 3,208 contacts, during a 20-year period (2000–2019) were investigated. All isolated polioviruses were tested for their wild or vaccine origin according to the WHO recommended protocol by PCR and sequencing analysis were performed. Enterovirus positivity was detected in a total of 915 cases, which were identified as 204 Sabin-like polio virus (SLPV) and 711 non-polio enterovirus (NPEV). Of the 204 SLPV, 141 (69.1%) AFP were detected in patients and 63 (30.9%) were detected in samples taken from their contacts. Of the 711 NPEVs, 516 (72.5%) were from AFP cases and 195 (27.5%) were detected in samples taken from their contacts. It is concluded that the reason for the higher detection rate of NPEV in samples from AFP pre-diagnosed cases is attributed to the polio vaccination rates reaching 97% between 2008 and 2019 in Turkey. The most frequently detected NPEV serotypes were Coxackie A24, B3, and Echo 30. This retrospective study is the first comprehensive study in Turkey to evaluate the results of the AFP surveillance in the last 20 years.

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Evaluation of the Functionality and Effectiveness of the CORE Group Polio Project’s Community-Based Acute Flaccid Paralysis Surveillance System in South Sudan

American Journal of Tropical Medicine and Hygiene ◽

10.4269/ajtmh.19-0120 ◽

2019 ◽

Vol 101 (4_Suppl) ◽

pp. 91-99 ◽

Cited By ~ 4

Author(s):

Anthony Kisanga ◽

Bausumo Abiuda ◽

Peter Walyaula ◽

Lee Losey ◽

Omongot Samson

Keyword(s):

Surveillance System ◽

Acute Flaccid Paralysis ◽

South Sudan ◽

Flaccid Paralysis ◽

Community Based ◽

Core Group ◽

The Core ◽

Acute Flaccid Paralysis Surveillance

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Acute Flaccid Paralysis surveillance system performance in Jordan, 2012-2016: a teaching case-study

Pan African Medical Journal ◽

10.11604/pamj.supp.2019.33.1.18606 ◽

2019 ◽

Vol 33 ◽

Author(s):

Fatima Zerriouh ◽

Yousef Khader ◽

Nabil Sabri ◽

Kamel Abusal ◽

Ibrahim Iblan ◽

...

Keyword(s):

System Performance ◽

Surveillance System ◽

Acute Flaccid Paralysis ◽

Flaccid Paralysis ◽

Teaching Case ◽

Acute Flaccid Paralysis Surveillance

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Enterovirus D68 Subclade B3 Circulation in Senegal, 2016: Detection from Influenza-like Illness and Acute Flaccid Paralysis Surveillance

Scientific Reports ◽

10.1038/s41598-019-50470-z ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 2

Author(s):

Amary Fall ◽

Ndack Ndiaye ◽

Mamadou Malado Jallow ◽

Mamadou Aliou Barry ◽

Cheikh Saad Bou Touré ◽

...

Keyword(s):

Active Surveillance ◽

Acute Flaccid Paralysis ◽

Flaccid Paralysis ◽

Influenza Like Illness ◽

Acute Flaccid Paralysis Surveillance ◽

Afp Surveillance ◽

Enterovirus D68 ◽

Low Levels ◽

Respiratory Specimens ◽

Children Under 5

Abstract Following the 2014 outbreak, active surveillance of the EV-D68 has been implemented in many countries worldwide. Despite subsequent EV-D68 outbreaks (2014 and 2016) reported in many areas, EV-D68 circulation remains largely unexplored in Africa except in Senegal, where low levels of EV-D68 circulation were first noted during the 2014 outbreak. Here we investigate subsequent epidemiology of EV-D68 in Senegal from June to September 2016 by screening respiratory specimens from ILI and stool from AFP surveillance. EV-D68 was detected in 7.4% (44/596) of patients; 40 with ILI and 4 with AFP. EV-D68 detection was significantly more common in children under 5 years (56.8%, p = 0.016). All EV-D68 strains detected belonged to the newly defined subclade B3. This study provides the first evidence of EV-D68 B3 subclade circulation in Africa from patients with ILI and AFP during a 2016 outbreak in Senegal. Enhanced surveillance of EV-D68 is needed to better understand the epidemiology of EV-D68 in Africa.

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