Metabolic associated fatty liver disease and acute-on-chronic liver failure

2022 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jacqueline Córdova-Gallardo ◽  
Andrew P. Keaveny ◽  
Xingshun Qi ◽  
Nahum Méndez-Sánchez
Keyword(s):  
Liver Disease ◽  
Liver Failure ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Chronic Liver ◽  
Chronic Liver Failure

Acute on chronic liver failure from nonalcoholic fatty liver disease: a growing and aging cohort with rising mortality

Hepatology ◽  
2020 ◽  
Author(s):  
Vinay Sundaram ◽  
Rajiv Jalan ◽  
Parth Shah ◽  
Ashwani K. Singal ◽  
Arpan A Patel ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Failure ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Chronic Liver ◽  
Chronic Liver Failure ◽  
Nonalcoholic Fatty Liver

Non-alcoholic fatty liver disease in HIV-positive patients predisposes for acute-on-chronic liver failure: two cases

2006 ◽  
Vol 18 (1) ◽  
pp. 101-105 ◽  
Author(s):  
Alisan Kahraman ◽  
Michael Miller ◽  
Robert K. Gieseler ◽  
Guido Gerken ◽  
Michael J. Scolaro ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Failure ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Chronic Liver ◽  
Hiv Positive ◽  
Chronic Liver Failure ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Global Burden of Non‐alcoholic Fatty Liver Disease (NAFLD) and chronic liver disease (CLD) Among Adolescents and Young Adults

Hepatology ◽  
2021 ◽  
Author(s):  
James M. Paik ◽  
Khaled Kabbara ◽  
Katherine E Eberly ◽  
Youssef Younossi ◽  
Linda Henry ◽  
...  
Keyword(s):  
Young Adults ◽  
Liver Disease ◽  
Fatty Liver ◽  
Chronic Liver Disease ◽  
Fatty Liver Disease ◽  
Chronic Liver ◽  
Adolescents And Young Adults ◽  
Global Burden ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

scholarly journals The Matrisome, Inflammation, and Liver Disease

2020 ◽  
Vol 40 (02) ◽  
pp. 180-188 ◽  
Author(s):  
Christine E. Dolin ◽  
Gavin E. Arteel
Keyword(s):  
Extracellular Matrix ◽  
Liver Disease ◽  
Fatty Liver ◽  
Chronic Liver Disease ◽  
Fatty Liver Disease ◽  
Chronic Liver ◽  
Disease Development ◽  
Disease States ◽  
Ecm Proteins

AbstractChronic fatty liver disease is common worldwide. This disease is a spectrum of disease states, ranging from simple steatosis (fat accumulation) to inflammation, and eventually to fibrosis and cirrhosis if untreated. The fibrotic stage of chronic liver disease is primarily characterized by robust accumulation of extracellular matrix (ECM) proteins (collagens) that ultimately impairs the function of the organ. The role of the ECM in early stages of chronic liver disease is less well-understood, but recent research has demonstrated that several changes in the hepatic ECM in prefibrotic liver disease are not only present but may also contribute to disease progression. The purpose of this review is to summarize the established and proposed changes to the hepatic ECM that may contribute to inflammation during earlier stages of disease development, and to discuss potential mechanisms by which these changes may mediate the progression of the disease.

scholarly journals Imaging Software-Based Sarcopenia Assessment in Gastroenterology: Evolution and Clinical Meaning

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Giovanni Marasco ◽  
Sinan Sadalla ◽  
Giulio Vara ◽  
Rita Golfieri ◽  
Davide Festi ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Liver Disease ◽  
Liver Failure ◽  
Chronic Liver Disease ◽  
Liver Diseases ◽  
Chronic Liver ◽  
Chronic Liver Failure ◽  
Cross Sectional ◽  
Cross Sectional Imaging ◽  
Sectional Imaging

Sarcopenia is gaining attention as a negative prognostic factor in different fields of medicine, including chronic liver failure. However, the assessment of sarcopenia in patients with liver diseases is often neglected due to unawareness of reliable tools and methods and thus is limited to research studies. Cross-sectional imaging is a diffuse diagnostic tool and is commonly performed in patients with chronic liver failure. The last advancements in radiology image analysis using dedicated software allow an easy and standardized method to assess skeletal muscle volume. Several measures can be obtained from cross-sectional imaging analysis to evaluate sarcopenia in patients affected by chronic liver disease. We aimed to review the recent advances in imaging-based sarcopenia assessment, in particular in patients with chronic liver diseases. As a result, we found that the skeletal muscle index (SMI) seems to be a reliable method to assess sarcopenia in cirrhotic patients. Even if further studies are needed to validate proper cut-offs for each clinical endpoint, physicians are invited to consider the assessment of sarcopenia in the work-up of patients with chronic liver disease.

Acute Liver Failure

2019 ◽  
pp. 264-269
Author(s):  
James Y. Findlay ◽  
Eelco F. M. Wijdicks
Keyword(s):  
Liver Disease ◽  
Liver Function ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Chronic Liver ◽  
Chronic Liver Failure ◽  
Underlying Liver Disease ◽  
Rapid Deterioration ◽  
Uncommon Condition ◽  
Acute Insult

Acute liver failure (ALF) is an uncommon condition in which an acute insult results in a rapid deterioration of liver function, encephalopathy, and coagulopathy in the absence of prior underlying liver disease. It is differentiated from rapid deterioration in the setting of underlying liver disease (acute on chronic liver failure) and from the gradual deterioration in liver function that can occur in chronic liver failure.

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