Successful First-Line Treatment With Propranolol Of Multifocal Infantile Hepatic Hemangioma With High Flow Cardiac Overload

2011 ◽  
pp. 1
Author(s):  
Marco Sciveres ◽  
Gianluca Marrone ◽  
Salvatore Pipitone ◽  
Silvia Riva ◽  
Marco Spada ◽  
...  
Keyword(s):  
High Flow ◽  
Hepatic Hemangioma ◽  
Line Treatment ◽  
First Line ◽  
First Line Treatment

scholarly journals Nasal high-flow oxygen versus noninvasive ventilation in acute exacerbation of COPD: protocol for a randomised noninferiority clinical trial

2020 ◽  
Vol 6 (4) ◽  
pp. 00114-2020
Author(s):  
Athanasia Papalampidou ◽  
Eleni Bibaki ◽  
Stylianos Boutlas ◽  
Ioannis Pantazopoulos ◽  
Nikolaos Athanasiou ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Noninvasive Ventilation ◽  
High Flow ◽  
Line Treatment ◽  
First Line ◽  
Hypercapnic Respiratory Failure ◽  
Acute Exacerbation Of Copd ◽  
High Flow Oxygen ◽  
Exacerbation Of Copd ◽  
First Line Treatment

BackgroundNoninvasive ventilation (NIV) is considered as the first-line treatment for acute exacerbation of COPD (AECOPD) complicated by respiratory acidosis. Recent studies demonstrate a role of nasal high-flow oxygen (NHF) in AECOPD as an alternative treatment in patients intolerant to NIV or with contraindications to it.AimThe study aimed to evaluate whether NHF respiratory support is noninferior compared to NIV in respect to treatment failure, defined as need for intubation or change to alternative treatment group, in patients with AECOPD and mild-to-moderate acute or acute-on-chronic hypercapnic respiratory failure.MethodsWe designed a multicentre, prospective, randomised trial on patients with AECOPD, who have pH<7.35 but >7.25 and PaCO2 >45 mmHg, in whom NIV is indicated as a first-line treatment. According to power analysis, 498 participants will be required for establishing noninferiority of NHF compared to NIV. Patients will be randomly assigned to receive NIV or NHF. Treatment will be adjusted to maintain SpO2 between 88%–92% for both groups. Arterial blood gases, respiratory variables, comfort, dyspnoea score and any pulmonary or extrapulmonary complications will be assessed at baseline, before treatment initiation, and at 1, 2, 4, 6, 12, 24, 48 h, then once daily from day 3 to patient discharge, intubation or death.ConclusionGiven the increasing number of studies demonstrating the physiological effects of NHF in COPD patients, we hypothesise that NHF respiratory support will be noninferior to NIV in patients with AECOPD and mild-to-moderate acute or acute on chronic hypercapnic respiratory failure.

scholarly journals Propranolol as first-line treatment for life-threatening diffuse infantile hepatic hemangioma: A case report

Hepatology ◽  
2017 ◽  
Vol 66 (1) ◽  
pp. 283-285 ◽  
Author(s):  
Giulia Varrasso ◽  
Amalia Schiavetti ◽  
Silvia Lanciotti ◽  
Maria Sapio ◽  
Eva Ferrara ◽  
...  
Keyword(s):  
Case Report ◽  
Hepatic Hemangioma ◽  
Line Treatment ◽  
First Line ◽  
Life Threatening ◽  
First Line Treatment

First-line treatment using high-flow nasal cannula for children with severe bronchiolitis: Applicability and risk factors for failure

2018 ◽  
Vol 25 (3) ◽  
pp. 213-218 ◽  
Author(s):  
C. Guillot ◽  
C. Le Reun ◽  
H. Behal ◽  
J. Labreuche ◽  
M. Recher ◽  
...  
Keyword(s):  
Risk Factors ◽  
High Flow ◽  
Nasal Cannula ◽  
Line Treatment ◽  
High Flow Nasal Cannula ◽  
First Line ◽  
First Line Treatment
Sign in / Sign up

Export Citation Format

Share Document