Partial Response to Sorafenib in a Child With a Myeloid/Lymphoid Neoplasm, Eosinophilia, and a ZMYM2-FLT3 Fusion

Background: Verruca is one of the common dermatopathologies which has multiple therapeutic options but with variable success rates, refractory cases and high recurrence rates. Nowadays, treatment with intralesional injections has gained recognition due to its effectiveness in clearing verrucae. These act by stimulating the cell-mediated immunity. Out of scores of options available for intralesional therapeutics, Vitamin D3 appears to be more promising but least evaluated. Therefore, we planned to evaluate the efficacy of intralesional Vitamin D3 in various types of cutaneous verrucae. Simultaneously the results were compared with intralesional bleomycin, also. Methods: A total of 200 patients of cutaneous verrucae with varying size and duration were included in the experimental randomized comparative study. We divided them into two groups. Group A, comprising of 100 patients, received 0.2-0.5 ml intralesional Vitamin D3 (600,000 IU, 15mg/ml) and Group B, also of hundred subjects, received intralesional Bleomycin (1 mg/ml) into the base of verrucae. A maximum of 5 verrucae were injected per session at 3 weeks interval until resolution or for a maximum of 4 sessions. Patients were followed up for 6 months after the last injection to assess the clearance status and detect any recurrence. Results: In Group A (Vitamin D3), 'Complete response', 'Partial response' and 'No response' were observed in 85.07%, 6.74% and 8.17% respectively after 4 sessions. Recurrence rate was 0.81% after 6 months. In Group B (Bleomycin), 'Complete response', 'Partial response' and 'No response' were found in 77.99%, 10.47% and 11.53% in the series. Recurrence rate was 1.71%, comparatively higher in group B. Conclusion: The efficacy of intralesional Vitamin D3 was found significantly higher as compared to intralesional Bleomycin in the treatment of cutaneous verrucae with less recurrence rates. Vitamin D3 has an additional advantage of cost-effective treatment over Bleomycin. We purpose its use, as a primary mode of treatment in various types of cutaneous verrucae. Keywords: Bleomycin, Vitamin D3, Verrucae.

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Supernatural Explanations and Inspirations

European Journal for Philosophy of Religion ◽

10.24204/ejpr.v9i3.1990 ◽

2017 ◽

Vol 9 (3) ◽

pp. 49-63

Author(s):

Stephen R. L. Clark

Keyword(s):

Partial Response ◽

Religious Traditions ◽

Religious Sensibility ◽

The Rich ◽

Supernatural Explanations

I propose, in partial response to the rich essays by Millican & Thornhill-Miller and Salamon that religious traditions are too diverse to be represented either by a cosmological core or even (though this is more plausible) an ethical. Religious sensibility is more often inspirational than explanatory, does not always require a transcendent origin of all things (however reasonable that thesis may be in the abstract), and does not always support the sort of humanistic values preferred in the European Enlightenment. A widely shared global religion is more likely to be eclectic than carefully ‘rational’, and is likely to be opposed by a more overtly ‘supernatural’ project founded in revelation.

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Faculty Opinions recommendation of Adjunctive therapy with pregabalin in generalized anxiety disorder patients with partial response to SSRI or SNRI treatment.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.714947819.790402847 ◽

2012 ◽

Author(s):

Hans Peter Volz

Keyword(s):

Anxiety Disorder ◽

Partial Response ◽

Generalized Anxiety Disorder ◽

Adjunctive Therapy ◽

Generalized Anxiety

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Maximum likelihood decoding of RLL-FEC array codes on partial response channels

Electronics Letters ◽

10.1049/el:19930942 ◽

1993 ◽

Vol 29 (16) ◽

pp. 1406 ◽

Cited By ~ 4

Author(s):

G.S. Markarian ◽

M. Naderi ◽

B. Honary ◽

A. Popplewell ◽

J.J. O'Reilly

Keyword(s):

Maximum Likelihood ◽

Partial Response ◽

Maximum Likelihood Decoding ◽

Partial Response Channels ◽

Array Codes

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Book Works’ Archive: a partial response

Art Libraries Journal ◽

10.1017/s0307472200018666 ◽

2013 ◽

Vol 38 (3) ◽

pp. 36-41

Author(s):

Karen Di Franco

Keyword(s):

Knowledge Transfer ◽

Partial Response ◽

Case Studies ◽

Classification System ◽

Research Centre ◽

Transfer Scheme ◽

The Arts ◽

Select Material ◽

Search Facility ◽

Working Processes

Since 2010, Book Works has been digitising material from its archive – whether finished works, ephemera, correspondence, photographs, or manuscripts – to give access to the working processes of the organisation (at www.bookworks.org.uk). The archive database is constructed around a chronological timeline and includes a search facility that allows visitors to filter and select material using a bespoke classification system. It currently comprises detailed content relating to two case studies from Book Works back catalogue: After the Freud Museum by Susan Hiller and Erasmus is late by Liam Gillick, as well as ephemera and material from other works. The project has been developed in collaboration with Ligatus Research Centre, University of the Arts London, with support from the AHRC Knowledge Transfer scheme.

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