scholarly journals Whither life? Conjectures on the future evolution of biochemistry

2016 ◽  
Vol 12 (8) ◽  
pp. 20160269 ◽  
Author(s):  
Jodi L. Brewster ◽  
Thomas J. Finn ◽  
Miguel A. Ramirez ◽  
Wayne M. Patrick

Life has existed on the Earth for approximately four billion years. The sheer depth of evolutionary time, and the diversity of extant species, makes it tempting to assume that all the key biochemical innovations underpinning life have already happened. But we are only a little over halfway through the trajectory of life on our planet. In this Opinion piece, we argue: (i) that sufficient time remains for the evolution of new processes at the heart of metabolic biochemistry and (ii) that synthetic biology is providing predictive insights into the nature of these innovations. By way of example, we focus on engineered solutions to existing inefficiencies in energy generation, and on the complex, synthetic regulatory circuits that are currently being implemented.

1984 ◽  
Vol 31 (3) ◽  
pp. 313-315 ◽  
Author(s):  
Samuel C. Vila

2018 ◽  
Vol 40 (2) ◽  
pp. 238-262
Author(s):  
Rodrigo Therezo
Keyword(s):  

This paper attempts to rethink difference and divisibility as conditions of (im)possibility for love and survival in the wake of Derrida's newly discovered—and just recently published—Geschlecht III. I argue that Derrida's deconstruction of what he calls ‘the grand logic of philosophy’ allows us to think love and survival without positing unicity as a sine qua non. This hypothesis is tested in and through a deconstructive reading of Heidegger's second essay on Trakl in On the Way to Language, where Heidegger's phonocentrism and surreptitious nationalism converge in an effort to ‘save the earth’ from a ‘degenerate’ Geschlecht that cannot survive the internal diremption between Geschlechter. I show that one way of problematizing Heidegger's claim is to point to the blank spaces in the ‘E i n’ of Trakl's ‘E i n Geschlecht’, an internal fissuring in the very word Heidegger mobilizes in order to secure the future of mankind.


2019 ◽  
pp. 75-89
Author(s):  
A.B. Lyubinin

The article comments on the concept of «socialism with Chinese specificity», which forms the ideological basis of the «Chinese miracle». The ideological origins of this concept, starting with Confucianism, are revealed. It has evolved to become increasingly pragmatic and to adapt to the realities of national and global development. The relation of this concept with the Marxist concept of socialism is shown. The article substantiates the fundamental theoretical thesis that in the objective-essential sense (in the elimination of, in particular, national specifics) Chinese society is a transitional form to socialism (a certain analogue of the Soviet society of the NEP period). The author talks about a «heterogeneous», «mixed» socio-economic system, the vector and nature of the future evolution of which will depend crucially on the strategic course of the CPC.


2017 ◽  
Author(s):  
Caroline A. Masiello ◽  
◽  
Jonathan J. Silberg ◽  
Hsiao-Ying Cheng ◽  
Ilenne Del Valle ◽  
...  

Author(s):  
Charles Dickens ◽  
Dennis Walder

Dombey and Son ... Those three words conveyed the one idea of Mr. Dombey's life. The earth was made for Dombey and Son to trade in, and the sun and moon were made to give them light.' The hopes of Mr Dombey for the future of his shipping firm are centred on his delicate son Paul, and Florence, his devoted daughter, is unloved and neglected. When the firm faces ruin, and Dombey's second marriage ends in disaster, only Florence has the strength and humanity to save her father from desolate solitude. This new edition contains Dickens's prefaces, his working plans, and all the original illustrations by ‘Phiz’. The text is that of the definitive Clarendon edition. It has been supplemented by a wide-ranging Introduction, highlighting Dickens's engagement with his times, and the touching exploration of family relationships which give the novel added depth and relevance.


2021 ◽  
Vol 503 (1) ◽  
pp. 594-602
Author(s):  
R Schiavi ◽  
R Capuzzo-Dolcetta ◽  
I Y Georgiev ◽  
M Arca-Sedda ◽  
A Mastrobuono-Battisti

ABSTRACT We use direct N-body simulations to explore some possible scenarios for the future evolution of two massive clusters observed towards the centre of NGC 4654, a spiral galaxy with mass similar to that of the Milky Way. Using archival HST data, we obtain the photometric masses of the two clusters, M = 3 × 105 M⊙ and M = 1.7 × 106 M⊙, their half-light radii, Reff ∼ 4 pc and Reff ∼ 6 pc, and their projected distances from the photometric centre of the galaxy (both <22 pc). The knowledge of the structure and separation of these two clusters (∼24 pc) provides a unique view for studying the dynamics of a galactic central zone hosting massive clusters. Varying some of the unknown cluster orbital parameters, we carry out several N-body simulations showing that the future evolution of these clusters will inevitably result in their merger. We find that, mainly depending on the shape of their relative orbit, they will merge into the galactic centre in less than 82 Myr. In addition to the tidal interaction, a proper consideration of the dynamical friction braking would shorten the merging times up to few Myr. We also investigate the possibility to form a massive nuclear star cluster (NSC) in the centre of the galaxy by this process. Our analysis suggests that for low-eccentricity orbits, and relatively long merger times, the final merged cluster is spherical in shape, with an effective radius of few parsecs and a mass within the effective radius of the order of $10^5\, \mathrm{M_{\odot }}$. Because the central density of such a cluster is higher than that of the host galaxy, it is likely that this merger remnant could be the likely embryo of a future NSC.


2016 ◽  
Vol 7 (6) ◽  
pp. 910-931 ◽  
Author(s):  
Rebecca M. B. Harris ◽  
Tomas A. Remenyi ◽  
Grant J. Williamson ◽  
Nathaniel L. Bindoff ◽  
David M. J. S. Bowman

2016 ◽  
Vol 10 (6) ◽  
pp. 2693-2719 ◽  
Author(s):  
Antoine Marmy ◽  
Jan Rajczak ◽  
Reynald Delaloye ◽  
Christin Hilbich ◽  
Martin Hoelzle ◽  
...  

Abstract. Permafrost is a widespread phenomenon in mountainous regions of the world such as the European Alps. Many important topics such as the future evolution of permafrost related to climate change and the detection of permafrost related to potential natural hazards sites are of major concern to our society. Numerical permafrost models are the only tools which allow for the projection of the future evolution of permafrost. Due to the complexity of the processes involved and the heterogeneity of Alpine terrain, models must be carefully calibrated, and results should be compared with observations at the site (borehole) scale. However, for large-scale applications, a site-specific model calibration for a multitude of grid points would be very time-consuming. To tackle this issue, this study presents a semi-automated calibration method using the Generalized Likelihood Uncertainty Estimation (GLUE) as implemented in a 1-D soil model (CoupModel) and applies it to six permafrost sites in the Swiss Alps. We show that this semi-automated calibration method is able to accurately reproduce the main thermal condition characteristics with some limitations at sites with unique conditions such as 3-D air or water circulation, which have to be calibrated manually. The calibration obtained was used for global and regional climate model (GCM/RCM)-based long-term climate projections under the A1B climate scenario (EU-ENSEMBLES project) specifically downscaled at each borehole site. The projection shows general permafrost degradation with thawing at 10 m, even partially reaching 20 m depth by the end of the century, but with different timing among the sites and with partly considerable uncertainties due to the spread of the applied climatic forcing.


Science ◽  
2015 ◽  
Vol 348 (6232) ◽  
pp. 296-296 ◽  
Author(s):  
T. Kuiken
Keyword(s):  

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