scholarly journals A novel poxvirus lethal to red squirrels (Sciurus vulgaris)

2003 ◽  
Vol 84 (12) ◽  
pp. 3337-3341 ◽  
Author(s):  
Kathryn Thomas ◽  
Daniel M. Tompkins ◽  
Anthony W. Sainsbury ◽  
Ann R. Wood ◽  
Robert Dalziel ◽  
...  

A parapoxvirus has been implicated in the decline of the red squirrel in the United Kingdom. Virus was isolated from an outbreak of lethal disease in red squirrels in the north-east of England. Experimental infection of captive-bred red squirrels confirmed that this virus was the cause of the severe skin lesions observed. Electron microscopic examination of the virus showed that it had a morphology typical of parapoxviruses whilst preliminary sequence data suggested a genomic G+C composition of approximately 66 %, again similar to that found in other parapoxviruses. However Southern hybridization analysis failed to detect three known parapoxvirus genes, two of which have been found so far only in the genus Parapoxvirus. Comparative sequence analysis of two other genes, conserved across the eight recognized chordopoxvirus genera, suggests that the squirrel virus represents a previously unrecognized genus of the Chordopoxviridae.

2009 ◽  
Vol 6 (2) ◽  
pp. 36-38 ◽  
Author(s):  
Zahid Latif

Ireland is the third largest island in Europe and the twentieth largest island in the world, with an area of 86 576 km2; it has a total population of slightly under 6 million. It lies to the north-west of continental Europe and to the west of Great Britain. The Republic of Ireland covers five-sixths of the island; Northern Ireland, which is part of the United Kingdom, is in the north-east. Twenty-six of the 32 counties are in the Republic of Ireland, which has a population of 4.2 million, and its capital is Dublin. The other six counties are in Northern Ireland, which has a population of 1.75 million, and its capital is Belfast. In 1973 both parts of Ireland joined the European Economic Community. This article looks at psychiatry in the Republic of Ireland.


Open Heart ◽  
2019 ◽  
Vol 6 (1) ◽  
pp. e000795 ◽  
Author(s):  
Linda Hicks ◽  
Julia Newton ◽  
Rahul Nayar ◽  
Kate Mackay

ObjectiveTo determine whether training podiatrists to provide opportunistic screening for atrial fibrillation (AF) during the local diabetes foot check was feasible and whether it detects previously unknown AF.MethodDuring the initiative, 45 podiatrists from across North Durham, Darlington and Durham Dales Easington and Sedgefield Clinical Commissioning Groups were trained to recognise heart irregularities when taking pulse readings of feet of patients with diabetes during their annual foot screening reviews.ResultsOver the course of the 3-month pilot, 5000 patients with diabetes had their feet pulse-tested. The project uncovered that for every 500 patients who had their feet checked, one new case of AF could be identified.ConclusionA report following the Podiatry and Atrial Fibrillation Case Finding scheme revealed that the National Health Service in the United Kingdom North East and North Cumbria area could benefit from potential cost savings in excess of £500 000. In 2013, the National Diabetes Information Service, Yorkshire and Humber Public Health Observatory estimated 231 777 people in the North East, North Cumbria, Hambleton and Richmondshire area with diabetes. Therefore 463 patients could be found with AF, preventing 23 strokes and saving £539 742 or in excess of £0.5 M.


Semiotica ◽  
2017 ◽  
Vol 2017 (216) ◽  
pp. 225-248 ◽  
Author(s):  
Ronnie Lippens

AbstractNational or local authorities regularly commission artists to build or construct sculptures and artworks destined for a place in a public space. Some of those sculptures and artworks are monumentally huge. Positioned in the open landscape, they are visible from a considerable distance. This contribution focuses on three such sculptures in the United Kingdom. The first, “Angel of the North,” was completed in 1998 and is standing at Gateshead in the North East of England. The second, “Anglo Saxon Warrior,” has not yet been built to a massive scale – although smaller, life-size versions were – but some debate has taken place in Stoke-on-Trent in North Staffordshire in the West Midlands about the possibility and remote likelihood of its construction. The third, “Golden,” is, however, at the time of writing, in the process of being assembled with an eye on erecting it, in 2014, at the very same location, Stoke-on-Trent. Proposals for all aforementioned artworks emerged against the backdrop of regional de-industrialization and were, at least partly, devised as an answer to economic and social deprivation in both regional localities. In this contribution an effort is made to tease out the symbolic intricacies embedded in all three artworks. Although all include references to what could be called the eternal origins of a mythical common law universe, each suggests, projects, and attempts to encode a moral and legal order in quite distinctly different ways.


Author(s):  
D.E. Holm ◽  
E. Van Wilpe ◽  
C.K. Harper ◽  
N.M. Duncan

Dermatosparaxis is a heritable collagen dysplasia causing skin extensibility and fragility. In Belgian Blue cattle this mutation has been described as a 3 base pair (bp) change followed by a 17 bp deletion in the gene coding for procollagen 1 N-Proteinase (pNPI). An outbreak in a commercial Drakensberger herd in South Africa followed the introduction in late 2000 of a 3-year-old bull that developed skin lesions in 2001 and was culled in 2002. Some of his offspring were similarly affected, 1 of which was kept as a breeding bull after his sire's death. Two affected calves were referred to the Onderstepoort Veterinary Academic Hospital in October 2005. Detailed examination revealed only skin abnormalities limited to the lateral extremities of the thorax, abdomen and pelvis, viz. either acute lacerations of varying sizes, slow healing defects or thin scars in chronic cases. During a subsequent farm visit, 13 animals with similar wounds were seen in the herd of 146 animals. Electron microscopic examination of skin biopsies revealed haphazard arrangement and loose packing of dermal collagen fibrils within collagen fibres. The fibrils showed size variation and slightly irregular outlines on cross-section, consistent with mild dermatosparaxis. DNA samples of affected calves were analysed using primers designed to amplify the region of the pNPI gene that contained the mutation described in Belgian Blue cattle, but this mutation could not be demonstrated in any of the animals tested. It is concluded that a form of dermatosparaxis with a different gene mutation from that described in Belgian Blue cattle exists in Drakensberger cattle in South Africa. This possibly also explains the milder and more delayed clinical signs and the milder dermal collagen ultrastructural abnormalities.


2019 ◽  
Vol 10 (1) ◽  
pp. 95-118 ◽  
Author(s):  
Nelli Stavropoulou

This article presents reflections from a participatory visual arts-based research study with individuals seeking asylum in the north-east of England. This study invited participants to represent their lived experiences through biographical and visual methods. In doing so, they engaged in a process of ethno-mimesis, accomplished through the production of images that function as sites for meaning making, self-representation and social critique. This article demonstrates how an arts-based approach can stimulate change and transformation in individuals’ lives by supporting meaningful participation in the knowledge production process and providing a safe space where participants are empowered by sharing stories that challenge, subvert and reimagine what it feels like to be an asylum seeker. Furthermore it suggests that in contrast to interview settings, through the process of ethno-mimesis participants were offered the time and space to consciously engage with their experiences and invest in their creativity and storytelling capacities in order to render their worldviews visible. Although the findings from this study reinforce an existing rich body of ethnographic work on lived experiences of asylum seekers, this study recognizes that the identified themes highlight the enduring impact of immigration policies on individuals asylum-seeking trajectories and focuses instead on how such experiences are creatively negotiated by participants.


Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 198 ◽  
Author(s):  
Susanna D.H. Mills ◽  
Julia A. Wolfson ◽  
Wendy L. Wrieden ◽  
Heather Brown ◽  
Martin White ◽  
...  

Cooking at home is likely to be associated with benefits to diet and health. However, the nuanced perceptions and practices linked to different types of cooking are not yet fully understood. This research aimed to explore the specific concept of ‘home cooking’, using qualitative research from the UK and US. Data from two previously completed studies exploring cooking at home were combined and a new secondary analysis was undertaken using the Framework Method. Data in the first study were drawn from participants in the North East of the UK who were interviewed. Data in the second study were drawn from participants in Baltimore, US, who took part in focus groups. Data from a total of 71 adults (18 UK and 53 US), with diverse sociodemographic characteristics and experiences of cooking, were analysed. In both countries, participants distinguished ‘home cooking’ as a distinct subtype of cooking at home. ‘Home cooking’ was defined in terms of preparing a meal from scratch, cooking with love and care, and nostalgia. Cooking at home had a range of dimensions, and perceptions of ‘home cooking’ tended to focus on social and emotional associations. In future, public health initiatives might, therefore, highlight the potential social and emotional benefits of ‘home cooking’, rather than emphasising implications for physical health.


Author(s):  
Nicola Livingstone

This chapter is a study of the ways in which property development elites use particular techniques and technologies of representation to create development real estate markets in the United Kingdom. It compares the construction of post-Brexit vote narratives of investment landscapes and opportunities in London and the North-East. London's real estate market is considered the leading destination for global capital flows into commercial real estate in the United Kingdom, and therefore it becomes the centrepiece of an evolving socio-technical system. The chapter specifically looks at the media narratives disseminated by real estate market agents in the aftermath of the Brexit referendum in London. It does so in order to question the role of media exposure and private consultancy firms and reflects on the way specialist expert knowledge is publicly disseminated to directly shape public opinion and, indirectly, real estate decision-making.


2017 ◽  
Vol 10 (2) ◽  
pp. 211-233 ◽  
Author(s):  
Maggie O'Neill ◽  
Susan Mansaray ◽  
Janice Haaken

This paper discusses a participatory arts-based research project undertaken with a refugee support organization in the United Kingdom, the Regional Refugee Forum North East (RRFNE), and a local women's group. The project used photography, storytelling, and walking methods to explore ways of seeing women's lived experiences, well-being, and sense of community in the context of their lives in the North East of England. Arts-based biographical methods, predominantly photo-walks, were undertaken within a participatory action research frame. Together the women cocreated a collective story that involved collaborative knowledge production as well as corporeal attunement and empathic witnessing through walking their stories of living in the North East of England.


2012 ◽  
Vol 50 (No. 6) ◽  
pp. 276-280 ◽  
Author(s):  
I. Literak ◽  
B. Smid ◽  
F. Dusbabek ◽  
R. Halouzka ◽  
L. Novotny

Nodular papillomatous lesions combined with proliferation and formation of scales and crusts were observed on both tarsi of a dead chaffinch (Fringilla coelebs) found in February 2004 in the eastern part of the Czech Republic. Electron microscopic examination demonstrated the presence of papillomavirus virions in the lesions. The parasitological examination of crust scraps revealed the presence of mites Knemidokoptes jamaicensis. Skin lesions were caused by a co-infection with the two pathogens. This paper is the first report of such a co-infection. In another chaffinch netted in May 2004 in the northern part of the Czech Republic, marked papillomatous lesions were found at the base of the beak. Proliferation of basal epidermal cells with sporadic intranuclear inclusions in the keratinocytes of stratum granulosum of the epidermis observed in the histopathological examination was suggestive of a viral aetiology of the papillomatous lesions. This is the first reported case of beak papillomatosis in the chaffinch.


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