scholarly journals Enhancement of ergocalciferol (vitamin D) content in mushrooms by UV irradiation

2017 ◽  
Vol 24 (3) ◽  
pp. 381-386 ◽  
Author(s):  
Seong-Jin Choi
Keyword(s):  
1990 ◽  
Vol 5 (10) ◽  
pp. 906-906
Author(s):  
N. Posthuma ◽  
P. T. A. M. Lips ◽  
A. J. M. Donker

2020 ◽  
Author(s):  
Satoshi Ochiai ◽  
Yoshihiro Nishida ◽  
Yoshitoshi Higuchi ◽  
Daigo Morita ◽  
Kazuya Makida ◽  
...  

Abstract Postmenopausal osteoporosis is crucial condition that reduces the QOL of affected patients just like aged type osteoporosis. The aim of this study was to evaluate the effectiveness of short-range UV-LED irradiation in postmenopausal osteoporosis using ovariectomized mice. Preliminary experiments identified the time of onset of osteoporosis after ovariectomy (8 weeks) in our model. We have set up a total of 4 groups (n=8/group); vitamin D-repletion with UV irradiation (Vit.D+UV+), vitamin D-repletion without UV irradiation (Vit.D+UV-), vitamin D-deficiency with UV irradiation (Vit.D-UV+), vitamin D-deficiency without UV irradiation (Vit.D-UV-), and. From 8 weeks after ovariectomy, UV was irradiated for 24 weeks. At the time of 16 and 24 weeks’ irradiation, serum Vit.D levels, various markers of bone metabolism, bone mineral density, and bone strength were evaluated, and histological analyses were performed. In addition, muscle strength was analyzed. Serum 25 (OH) D levels at 40 and 48 weeks of age were increased in the Vit.D-UV + group compared to the Vit.D-UV-group. Cortical thickness evaluated with micro-CT and strength of bone were significantly higher in Vit.D-UV+ group than those in Vit.D-UV- group. There was no difference in muscle strength between Vit.D-UV+ group and Vit.D-UV- group. No obvious adverse effects were observed in UV-irradiated mice including skin findings. Short-range UV irradiation may ameliorate postmenopausal osteoporosis associated with a state of vitamin D deficiency.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Satoshi Ochiai ◽  
Yoshihiro Nishida ◽  
Yoshitoshi Higuchi ◽  
Daigo Morita ◽  
Kazuya Makida ◽  
...  

AbstractPostmenopausal osteoporosis is crucial condition that reduces the QOL of affected patients just like aged type osteoporosis. The aim of this study was to evaluate the effectiveness of short-range UV-LED irradiation in postmenopausal osteoporosis using ovariectomized mice. Preliminary experiments identified the time of onset of osteoporosis after ovariectomy (8 weeks) in our model. We have set up a total of 4 groups (n = 8/group); vitamin D-repletion with UV irradiation (Vit.D+UV+), vitamin D-repletion without UV irradiation (Vit.D+UV−), vitamin D-deficiency with UV irradiation (Vit.D-UV+), vitamin D-deficiency without UV irradiation (Vit.D-UV−), and. From 8 weeks after ovariectomy, UV was irradiated for 24 weeks. At the time of 16 and 24 weeks’ irradiation, serum Vit.D levels, various markers of bone metabolism, bone mineral density, and bone strength were evaluated, and histological analyses were performed. In addition, muscle strength was analyzed. Serum 25-hydroxyvitamin D [25 (OH) D] levels at 40 and 48 weeks of age were increased in the Vit.D-UV+ group compared to the Vit.D-UV−group. Cortical thickness evaluated with micro-CT and strength of bone were significantly higher in Vit.D-UV+ group than those in Vit.D-UV− group. There was no difference in muscle strength between Vit.D-UV+ group and Vit.D-UV− group. No obvious adverse effects were observed in UV-irradiated mice including skin findings. Short-range UV irradiation may ameliorate postmenopausal osteoporosis associated with a state of vitamin D deficiency.


2015 ◽  
Vol 14 (12) ◽  
pp. 2138-2146 ◽  
Author(s):  
Fan Xiang ◽  
Robyn Lucas ◽  
Frank de Gruijl ◽  
Mary Norval

Does skin colour influence the production of vitamin D metabolites following UV irradiation? The paper reviews the studies addressing this important question and discusses possible reasons for the contradictory results.


2019 ◽  
Vol 116 (49) ◽  
pp. 24527-24532 ◽  
Author(s):  
Elizabeth G. Duchow ◽  
Nancy E. Cooke ◽  
Jeremy Seeman ◽  
Lori A. Plum ◽  
Hector F. DeLuca

Vitamin D is produced in the skin following exposure to sunlight. Ultraviolet (UV) B (UVB, 280–310 nm) results in isomerization of 7-dehydrocholesterol to previtamin D that spontaneously isomerizes to vitamin D. This pool of skin-derived vitamin D is the major source of vitamin D for animals. However, the mechanisms by which it becomes available remain undefined. It has been assumed that cutaneous vitamin D is transported into the circulation by vitamin D binding protein (DBP), but experimental evidence is lacking. To determine whether cutaneous vitamin D is transported by DBP, we utilized DBP−/− mice that were made vitamin D-deficient. These animals lack measurable 25(OH)D in blood and are hypocalcemic. As controls, DBP+/+ animals were vitamin D depleted and made equally hypocalcemic. UV irradiation of DBP+/+ animals restored serum calcium and serum 25(OH)D while the same treatment of DBP−/− animals failed to show either a serum calcium or 25(OH)D response despite having normal vitamin D production in skin. Intravenous injection of small amounts of recombinant DBP to the vitamin D-deficient DBP−/− mice restored the response to UV light. These results demonstrate a requirement for DBP to utilize cutaneously produced vitamin D.


1999 ◽  
pp. 249-255
Author(s):  
R. Krause ◽  
M. Bühring ◽  
A. M. Sharma ◽  
W. Hopfenmüller ◽  
T. C. Chen ◽  
...  

2017 ◽  
Vol 41 ◽  
pp. 330-336 ◽  
Author(s):  
Diego Morales ◽  
Alicia Gil-Ramirez ◽  
Fhernanda R. Smiderle ◽  
Adriana J. Piris ◽  
Alejandro Ruiz-Rodriguez ◽  
...  

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