scholarly journals Blood glucose levels in elderly subjects with type 2 diabetes during COVID-19 outbreak: a retrospective study in a single center

2020 ◽  
Author(s):  
Ting Xue ◽  
Qianwen Li ◽  
Qiongyao Zhang ◽  
Wei Lin ◽  
Junping Wen ◽  
...  
Keyword(s):  
Public Health ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Elderly Subjects ◽  
Glucose Levels ◽  
Public Health Emergencies ◽  
Blood Glucose Levels ◽  
Fasting Plasma

AbstractAimsIdeal glycemic control is of great importance for diabetic patients during public health emergencies of infectious diseases as long-term hyperglycemic are not only associated with chronic complications but also vital drivers of common and life-threatening infections. The present study was designed to investigate the changes of blood glucose levels in elderly subjects with type 2 diabetes(T2D) during COVID-19 outbreak.MethodsThis retrospective study focused on the T2D outpatients at Fujian Provincial Hospital aged 65 years old and above who received baseline test for fasting plasma glucose and/or glycated hemoglobin (HbA1c) between January 1, 2019 and March 8, 2019 and were followed up on fasting plasma glucose and/or HbA1c in the same period in 2020. The baseline and follow-up data were analyzed with the paired-samples T-test.ResultsA total of 135 elderly subjects with T2D with baseline and follow-up fasting plasma glucose and 50 elderly subjects with T2D with baseline and follow-up HbA1c were analyzed, respectively. The baseline and follow-up fasting plasma glucose were 7.08 ± 1.80 and 7.48±2.14 mmol/L, respectively (P=0.008). The baseline and follow-up HbA1c were 7.2±1.7% and 7.4±1.8%, respectively (P=0.158).ConclusionsElderly subjects with T2D had higher fasting plasma glucose levels during COVID-19 outbreak. We should pay more attension to the management of diabetics during public health emergencies.

scholarly journals Adherence to a food group-based dietary guideline and incidence of prediabetes and type 2 diabetes

2019 ◽  
Vol 59 (5) ◽  
pp. 2159-2169 ◽  
Author(s):  
Nicolette R. den Braver ◽  
Femke Rutters ◽  
Andrea L. J. Kortlever van der Spek ◽  
Dorina Ibi ◽  
Moniek Looman ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Lower Incidence ◽  
Food Group ◽  
Glucose Levels ◽  
Fasting Plasma ◽  
Total Data

Abstract Purpose In this study, we investigated the association between adherence to the Dutch Healthy Diet index 2015 (DHD15-index) and incidence of prediabetes (preT2D) and Type 2 Diabetes (T2D) in a representative sample for the general Dutch population. Methods Two prospective cohort studies, The Hoorn and The New Hoorn Study, were used for data analyses. In total, data from 2951 participants without diabetes at baseline (mean age 56.5 ± 7.5 years; 49.6% male) were harmonized. Baseline dietary intake was assessed with validated Food Frequency Questionnaires and adherence to the DHD15-index was calculated (range 0–130). PreT2D and T2D were classified according to the WHO criteria 2011. Poisson regression was used to estimate prevalence ratios between participant scores on the DHD15-index and preT2D and T2D, adjusted for follow-up duration, energy intake, socio-demographic, and lifestyle factors. Change in fasting plasma glucose levels (mmol/L) over follow-up was analysed using linear regression analyses, additionally adjusted for baseline value. Results During a mean follow-up of 6.3 ± 0.7 years, 837 participants developed preT2D and 321 participants developed T2D. The highest adherence to the DHD15-index was significantly associated with lower T2D incidence [model 3, PRT3vsT1: 0.70 (0.53; 0.92), ptrend = 0.01]. The highest adherence to the DHD15-index pointed towards a lower incidence of preT2D [PRT3vsT1: 0.87 (0.74; 1.03), ptrend = 0.11]. Higher adherence to the DHD15-index was not associated with change in fasting plasma glucose levels [β10point: − 0.012 (− 0.034; 0.009)mmol/L]. Conclusion The present study showed that the highest compared to the lowest adherence to the DHD15-index was associated with a lower T2D incidence, and pointed towards a lower incidence of preT2D. These results support the benefits of adhering to the guidelines in T2D prevention.

scholarly journals GAMBARAN KADAR GLUKOSA DARAH PADA PASIEN SKA DI RSUP PROF DR. R.D. KANDOU MANADO PERIODE JANUARI – DESEMBER 2014

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Hisky Malutu ◽  
Victor F. F. Joseph ◽  
Janry Pangemanan
Keyword(s):  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Stress Hyperglycemia ◽  
Glucose Levels ◽  
Coronary Syndrome ◽  
Blood Glucose Levels ◽  
Type 2 Dm ◽  
Fasting Plasma ◽  
Male Patients

Abstract: Acute Coronary Syndrome (ACS) is a collection of symptoms caused by acute myocardial ischemia. Over the past decade, several studies linking hyperglycemia on admission to higher mortality rate of patients with ACS, including acute myocardial infarction (AMI). This study aimed to obtain the profile of blood glucose levels among ACS patients at Prof. Dr. R.D. Kandou Hospital Manado from January to December 2014. This was an observational descriptive study with a retrospective approach. The results showed that there were 126 ACS patients; 21 patients were eligible for inclusion criteria. The number of male patients are higher than of female patients; most patients aged >60 years old; and the most type of ACS was unstable angina pectoris. Of the 21 patients, there were 6 patients with type 2 DM. Conclusion: Plasma glucose levels in ACS patients on admission tend to be normal, but fasting plasma glucose is higher in the NSTEMI and STEMI patients. Keywords: ACS, type 2 DM, stress hyperglycemia, admission, plasma glucose, fasting plasma glucose  Abstrak: Sindroma Koroner Akut (SKA) adalah kumpulan gejala yang disebabkan oleh iskemik miokard akut. Selama dekade terakhir ini, beberapa studi menghubungkan hiperglikemia pada saat masuk rumah sakit dengan angka mortalitas yang semakin tinggi pada pasien dengan SKA, termasuk Infark Miokard Akut (IMA). Penelitian ini bertujuan untuk mengetahui gambaran kadar glukosa darah pada pasien SKA di RSUP Prof Dr. R. D. Kandou Manado periode Januari – Desember 2014. Penelitian ini menggunakan metode deskriptif observasional dengan pendekatan studi retrospektif. Hasil penelitian mendapatkan 126 pasien SKA tetapi yang memenuhi kriteria inklusi hanya 21 saja. Penderita laki-laki lebih banyak dibandingkan perempuan, golongan usia terbanyak >60 tahun, dan jenis SKA terbanyak ialah angina pektoris tidak stabil. Didapatkan pula 6 pasien dengan riwayat DM tipe 2 sebelumnya dan 15 pasien tanpa riwayat DM tipe 2. Simpulan: Kadar glukosa darah sewaktu pada pasien SKA cenderung normal, tetapi kadar glukosa darah puasa meningkat pada jenis STEMI dan NSTEMI. Kata kunci: SKA, DM tipe 2, stres hiperglikemik, glukosa darah sewaktu, glukosa darah puasa

scholarly journals A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

2008 ◽  
Vol 41 (1) ◽  
pp. 89-94 ◽  
Author(s):  
Nabila Bouatia-Naji ◽  
Amélie Bonnefond ◽  
Christine Cavalcanti-Proença ◽  
Thomas Sparsø ◽  
Johan Holmkvist ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Diabetes Risk ◽  
Glucose Levels ◽  
Fasting Plasma

scholarly journals Randomized, Double-Blinded, Double-Dummy, Active-Controlled, and Multiple-Dose Clinical Study Comparing the Efficacy and Safety of Mulberry Twig (Ramulus Mori, Sangzhi) Alkaloid Tablet and Acarbose in Individuals with Type 2 Diabetes Mellitus

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Mengyi Li ◽  
Xuemin Huang ◽  
Hui Ye ◽  
Yao Chen ◽  
Jing Yu ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Clinical Trial ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Efficacy And Safety ◽  
Postprandial Plasma Glucose ◽  
Glucose Levels ◽  
Fasting Plasma ◽  
Significant Difference

Aims. To evaluate the efficacy and safety of mulberry twig alkaloid (SZ-A) tablet compared with acarbose in patients with type 2 diabetes.Methods. This clinical trial enrolled 38 patients who were randomized into two groups (SZ-A: 23; acarbose: 15) and were treated for 24 weeks. Patients and clinical trial staffs were masked to treatment assignment throughout the study. The primary outcome measures were glycated hemoglobin (HbA1c) and 1-hour and 2-hour postprandial and fasting plasma glucose levels from baseline to the end of treatment. Analysis included all patients who completed this study.Results. By the end of this study, HbA1c level in SZ-A group was decreased from baseline significantly (P<0.001). No significant difference was found when compared with acarbose group (P=0.652). Similarly, 1-hour and 2-hour postprandial plasma glucose levels in SZ-A group were decreased from baseline statistically (P<0.05), without any significant differences compared with acarbose group (P=0.748and 0.558, resp.). The fasting plasma glucose levels were not significantly changed in both groups. One of 23 patients in SZ-A group (4.76%) and 5 of 15 patients in acarbose group (33.33%) suffered from gastrointestinal adverse events.Conclusions. Compared with acarbose, SZ-A tablet was effective and safe in glycemic control in patients with type 2 diabetes.

scholarly journals A STUDY OF PLASMA GLUCOSE AND SERUM CERULOPLASMIN IN TYPE-2 DIABETES MELLITUS (T2DM) AT A TERTIARY CARE HOSPITAL

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Mukul Sharma ◽  
Kapil Bhatia ◽  
Pratibha Misra ◽  
Sibin MK ◽  
Vivek N Ambade ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Care Hospital ◽  
Serum Ceruloplasmin ◽  
Glucose Levels ◽  
Fasting Plasma

Introduction: Diabetes mellitus (DM) is a metabolic disorder occurring due to either defect in the secretion of insulin or defect in the action of insulin characterized by hyperglycemia. Hyperglycemia causes oxidative stress due to increased production of mitochondrial Reactive oxygen species (ROS) in T2DM. Ceruloplasmin (Cp) acts as an antioxidant through its ferroxidase activity. There is an association between the raised serum Cp levels and elevated plasma glucose levels in Type-2 Diabetes mellitus (T2DM) patients. Aim and objectives: The aim of this study is to evaluate the correlation between the fasting plasma glucose (FPG), 2hour plasma glucose (2hPG), and serum Cp level in T2DM patients as compared to non diabetics. Materials and methods: 165 cases of T2DM were recruited along with the 40 healthy age and sex matched controls. The blood samples were analyzed for serum Cp and FPG and 2hPG after 75-gram oral glucose. Results: The serum Cp levels of the patient group with T2DM were significantly higher than the control group (p = 0.000). There was a significant positive association between serum Cp level and 2hPG level of the patient population (r = 0.283, p = 0.000), but there was no significant correlation found between serum Cp levels and fasting plasma glucose levels in patients (r = 0.146, p =0.061). Similar findings were seen in the sub group analysis. Conclusion: Our study concludes a significant positive correlation between serum Cp and 2hPG levels in T2DM patients. Hence Cp levels may be considered as a part of the routine diagnostic panel to assess diabetes mellitus. Keywords: Serum Ceruloplasmin, Type-2 Diabetes Mellitus, Fasting plasma glucose, 2hour plasma glucose

scholarly journals A Five-year Follow-up Study of Fasting Plasma Glucose Levels in 3,604 Subjects Undergoing Health Screening.

2001 ◽  
Vol 28 (4) ◽  
pp. 429-433
Author(s):  
Hidetaka HORIE ◽  
Yoko SHIBATA ◽  
Shinji MITSUHASHI ◽  
Fumitoshi OHNO ◽  
Seiki SHIINO ◽  
...  
Keyword(s):  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Health Screening ◽  
Glucose Levels ◽  
Follow Up Study ◽  
Fasting Plasma
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