scholarly journals Field-deployable, rapid diagnostic testing of saliva samples for SARS-CoV-2

Author(s):  
Shan Wei ◽  
Esther Kohl ◽  
Alexandre Djandji ◽  
Stephanie Morgan ◽  
Susan Whittier ◽  
...  

AbstractRapid, scalable, point-of-need, COVID-19 diagnostic testing is necessary to safely re-open economies and prevent future outbreaks. We developed an assay that detects single copies of SARS-CoV-2 virus directly from saliva and swab samples in 30 min using a simple, one-step protocol that utilizes only a heat block and microcentrifuge tube prefilled with a mixture containing the necessary reagents and has a sensitivity and specificity of 97% and 100%, respectively.

2021 ◽  
Vol 1 ◽  
pp. e1236
Author(s):  
Alejandro M. Hasslocher-Moreno ◽  
Ingebourg Georg ◽  
Luiz H. C. Sangenis ◽  
Mauro F. F. Mediano

Introduction: Chagas disease (CD) is a neglected tropical disease. In the chronic phase of CD, the diagnosis is essentially serologic. Conventional reactions are currently in use. More recently, the use of rapid diagnostic testing (RDT) is indicated when conventional techniques are not available. Objective: To evaluate the sensitivity and specificity of RDTs for chronic CD diagnosis. Methodology: Individuals under suspicion of CD were evaluated using ELISA, Chemiluminescence (ChLIA) and RDT tests. Results: The RDT showed 95.1% sensitivity and 96.7% specificity, respectively. Conclusion: The findings of the present study showed that RDT used in the diagnosis of CD at a referral center in Brazil were not able to detect all CD cases when compared to Elisa and ChLIA.


2016 ◽  
Vol 51 (10) ◽  
pp. 815-822 ◽  
Author(s):  
Angel Heyerly ◽  
Ron Jones ◽  
Gordon Bokhart ◽  
Mary Shoaff ◽  
Douglas Fisher

2020 ◽  
Vol 58 (10) ◽  
pp. e245-e246
Author(s):  
Shaun S. Tan ◽  
Sharon Saw ◽  
Gabriel Yan ◽  
Ai Teng Chong ◽  
Zhixin Yang ◽  
...  

PLoS ONE ◽  
2017 ◽  
Vol 12 (11) ◽  
pp. e0188047 ◽  
Author(s):  
Amanda VanSteelandt ◽  
Josephine Aho ◽  
Kristyn Franklin ◽  
Jacques Likofata ◽  
Jean Baptiste Kamgang ◽  
...  

2003 ◽  
Vol 8 (10) ◽  
pp. 876-883 ◽  
Author(s):  
Clinton K. Murray ◽  
David Bell ◽  
Robert A. Gasser ◽  
Chansuda Wongsrichanalai

2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Maya Beganovic ◽  
Tristan T Timbrook ◽  
Sarah M Wieczorkiewicz

Abstract Antimicrobial stewardship (AMS) programs integrated with rapid diagnostic tests optimize patient outcomes and reduce time to effective therapy (TTET) and time to optimal therapy (TTOT). This study identifies predictors of TTET and TTOT among patients with positive blood cultures and identifies limitations to current TTOT definitions and outcomes.


2018 ◽  
Vol 4 (1) ◽  
pp. 12-15 ◽  
Author(s):  
Rapeeporn Wongkanya ◽  
Tippawan Pankam ◽  
Shauna Wolf ◽  
Supanit Pattanachaiwit ◽  
Jureeporn Jantarapakde ◽  
...  

2017 ◽  
Vol 65 (10) ◽  
pp. 1769-1770 ◽  
Author(s):  
Gabriele Rossi ◽  
Martin De Smet ◽  
Nimol Khim ◽  
Jean-Marie Kindermans ◽  
Didier Menard

2016 ◽  
Vol 64 (1) ◽  
pp. 15-23 ◽  
Author(s):  
Tristan T. Timbrook ◽  
Jacob B. Morton ◽  
Kevin W. McConeghy ◽  
Aisling R. Caffrey ◽  
Eleftherios Mylonakis ◽  
...  

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