Seroprevalence of Hospital Staff in Province with Zero COVID-19 cases

BACKGROUND. COVID-19 seroprevalence data has been scarce, especially in less developed countries with a relatively low infection rate. METHODS. A locally developed rapid IgM/IgG test kit was used for screening hospital staff in Ranong hospital which located in a province with zero COVID-19 prevalence in Thailand from April 17 to May 17, 2020. A total of 844 participants were tested; 82 of which were tested twice with one month apart. (Thai Clinical Trials Registry: TCTR20200426002) RESULTS. Overall, 0.8% of the participants (7 of 844) had positive immunoglobulin M (IgM), none had positive immunoglobulin G (IgG). Female staffs seemed to have higher IgM seropositive than male staffs (1.0% vs. 0.5%). None of the participants with a history of travel to the high-risk area or a history of close contact with PCR-confirmed COVID-19 case had developed antibodies against SARS-CoV-2. Among 844 staff, 811 had no symptom and six of them developed IgM seropositive (0.7%) while 33 had minor symptoms and only one of them developed IgM seropositive (3.0%). No association between IgM antibody against SARS-CoV-2 status and gender, history of travel to a high-risk area, history of close contact with PCR-confirmed COVID-19 case, history of close contact with suspected COVID-19 case, presence of symptoms within 14 days, or previous PCR status was found. None of the hospital staff developed IgG against SARS-CoV-2. CONCLUSION. COVID-19 antibody test could detect a substantial number of hospital staffs who could be potential silent spreaders in a province with zero COVID-19 case. Antibody testing should be encouraged for mass screening, especially in asymptomatic healthcare workers.

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COVID-19 Antibody in Thai Community Hospitals

10.1101/2020.06.24.20139188 ◽

2020 ◽

Author(s):

Tanawin Nopsopon ◽

Krit Pongpirul ◽

Korn Chotirosniramit ◽

Narin Hiransuthikul

Keyword(s):

Antibody Test ◽

Hospital Staff ◽

Developed Countries ◽

Immunoglobulin M ◽

Upper Respiratory Tract ◽

Community Hospitals ◽

Antibody Testing ◽

Test Kit ◽

Seroprevalence Data ◽

Asymptomatic Individuals

AbstractBackgroundCOVID-19 seroprevalence data has been scarce, especially in less developed countries with a relatively low infection rate.MethodsA locally developed rapid IgM/IgG test kit was used for screening hospital staff and patients who required procedural treatment or surgery in 52 hospitals in Thailand from April 8 to June 26, 2020. A total of 857 participants were tested—675 were hospital staff and 182 were pre-procedural patients. (Thai Clinical Trials Registry: TCTR20200426002)ResultsOverall, 5.5% of the participants (47 of 857) had positive immunoglobulin M (IgM), 0.2% (2 of 857) had positive immunoglobulin G (IgG) and IgM. Hospitals located in the Central part of Thailand had the highest IgM seroprevalence (11.9%). Preprocedural patients had a higher rate of positive IgM than the hospital staff (12.1% vs. 3.7%). Participants with present upper respiratory tract symptoms had a higher rate of positive IgM than those without (9.6% vs. 4.5%). Three quarters (80.5%, 690 of 857) of the participants were asymptomatic, of which, 31 had positive IgM (4.5%) which consisted of 20 of 566 healthcare workers (3.5%) and 11 of 124 preprocedural patients (8.9%).ConclusionsCOVID-19 antibody test could detect a substantial number of potential silent spreaders in Thai community hospitals. Antibody testing should be encouraged for mass screening, especially in asymptomatic individuals.

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Seroprevalence of hospital staff in a province with zero COVID-19 cases

PLoS ONE ◽

10.1371/journal.pone.0238088 ◽

2021 ◽

Vol 16 (4) ◽

pp. e0238088

Author(s):

Tanawin Nopsopon ◽

Krit Pongpirul ◽

Korn Chotirosniramit ◽

Wutichai Jakaew ◽

Chuenkhwan Kaewwijit ◽

...

Keyword(s):

Clinical Trials ◽

Close Contact ◽

Antibody Test ◽

Hospital Staff ◽

Institutional Review Board ◽

Risk Area ◽

High Risk Area ◽

Institutional Review ◽

History Of ◽

Clinical Trials Registry

Background COVID-19 seroprevalence data, particularly in less developed countries with a relatively low incidence, has been scant. We aimed to explore the seroprevalence of hospital staff in the area with zero confirmed COVID-19 case to shed light on the situation of COVID-19 infection in zero or low infection rate countries where mass screening was not readily available. Methods A locally developed rapid immunoglobulin M (IgM)/immunoglobulin G (IgG) test kit was used for hospital staff screening of Ranong hospital which is located in a province with zero COVID-19 prevalence in Thailand from 17th April to 17th May 2020. All staff was tested, 100 of which were randomly invited to have a repeating antibody test in one month. (Thai Clinical Trials Registry: TCTR20200426002) Results Of 844 hospital staff, 82 were tested twice one month apart (response rate for repeating antibody test 82%). Overall, 0.8% of the participants (7 of 844) had positive IgM, none had positive IgG. Female staff had 1.0% positive IgM (95% CI: 0.5–2.1%) while male had 0.5% positive IgM (95% CI: 0.1–2.6%). No participants with a history of travel to the high-risk area or close contact with PCR-confirmed COVID-19 case developed SARS-CoV-2 antibodies. Among 844 staff, 811 had no symptoms and six of them developed IgM seropositive (0.7%) while 33 had minor symptoms and only one of them developed IgM seropositive (3.0%). No association between SARS-CoV-2 IgM status and gender, history of travel to a high-risk area, close contact with PCR-confirmed or suspected COVID-19 case, presence of symptoms within 14 days, or previous PCR status was found. None of the hospital staff developed SARS-CoV-2 IgG. Conclusions COVID-19 antibody test could detect a considerable number of hospital staff who could be potential silent spreaders in a province with zero COVID-19 cases. Accurate antibody testing is a valuable screening tool, particularly in asymptomatic healthcare workers. Trial registration: This study was approved by the Institutional Review Board of Chulalongkorn University (IRB No.236/63) and the Institutional Review Board of Ranong Hospital. (Thai Clinical Trials Registry: TCTR20200426002).

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Natural history of esophageal and gastric cardia precursor by repetitive endoscope screening with 425 adults in a high-risk area in China

Cancer Epidemiology ◽

10.1016/j.canep.2009.06.002 ◽

2009 ◽

Vol 33 (2) ◽

pp. 108-112 ◽

Cited By ~ 7

Author(s):

Deng Gui Wen ◽

Shi Jie Wang ◽

Li Wei Zhang ◽

Wendi Zhou ◽

Wei Fang Yu ◽

...

Keyword(s):

High Risk ◽

Natural History ◽

Gastric Cardia ◽

Risk Area ◽

High Risk Area ◽

History Of

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PROPOSAL FOR UTILIZATION OF COMMUNITY DISASTER MANAGEMENT PLAN SYSTEM IN FLOOD HIGH RISK AREA -IN THE CASE ON EVACUATION BEHAVIOR OF DISABLED PERSON AT HEAVY RAIN DISASTER-

Journal of Japan Society of Civil Engineers Ser F6 (Safety Problem) ◽

10.2208/jscejsp.75.2_i_75 ◽

2019 ◽

Vol 75 (2) ◽

pp. I_75-I_82

Author(s):

Chikako ISOUCHI ◽

Yukiko TSUDA ◽

Atsuko NONOMURA

Keyword(s):

High Risk ◽

Disaster Management ◽

Heavy Rain ◽

Management Plan ◽

Risk Area ◽

High Risk Area ◽

Evacuation Behavior

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74 Improving Handover Between Doctors and Nurses on An Elderly Care Ward

Age and Ageing ◽

10.1093/ageing/afab030.35 ◽

2021 ◽

Vol 50 (Supplement_1) ◽

pp. i12-i42

Author(s):

K Suseeharan ◽

T Vedutla

Keyword(s):

High Risk ◽

Patient Care ◽

Positive Impact ◽

Elderly Care ◽

Task Completion ◽

Risk Area ◽

High Risk Area ◽

Staff Members ◽

Care Ward ◽

Doctors And Nurses

Abstract Background The Royal College of Physician guidelines (2011) identified handover as a “high risk step” in patient care, especially in recent times within the NHS where shift patterns lead to more disjointed care with a high reliance on effective handover by all staff members. Introduction At Cannock Chase hospital, Fairoak ward is an elderly care rehabilitation ward where there is a large multi-disciplinary team. While working on the ward as doctors we noticed that handover between the MDT was poor. Anecdotal evidence from both doctors and nurses felt that this was a high risk area in need of improvement. Aim to improve handover between doctors and nurses on this elderly care ward. Method To measure the quality of current handover practice we did a questionnaire. A total of 12 questionnaires were completed which showed that 92% of staff felt that handover on the ward was very poor and 50% preferred both written and verbal handover. We measured the number of tasks verbally handed over between doctors and nurses over 3 days. On average 65% of the tasks were completed. We then made the below interventions and re-audited to see if there was any improvement. Interventions over 3 week period: Results Questionnaire: Measuring task completion after interventions; Conclusion This project has made a positive change qualitatively and quantitatively to the ward handover practice. Staff satisfaction regarding handover has improved and the number of “handed over” tasks completed daily has significantly improved. The written handover sheet had poor utilisation by staff but in 4 months we are going to re-audit and trial the handover sheet again to further improve service delivery. We hope this improvement will have a positive impact on patient care on this elderly care ward.

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S2031 Socioeconomic Status in Relation to Esophageal Cancer in a High-Risk Area of Iran

Gastroenterology ◽

10.1016/s0016-5085(08)61401-8 ◽

2008 ◽

Vol 134 (4) ◽

pp. A-301 ◽

Cited By ~ 2

Author(s):

Farhad Islami ◽

Farin Kamangar ◽

Dariush Nasrollahzadeh ◽

Masoud Sotoudeh ◽

Christian C. Abnet ◽

...

Keyword(s):

Socioeconomic Status ◽

Esophageal Cancer ◽

High Risk ◽

Risk Area ◽

High Risk Area

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Innovative Road — a High-Risk Area

Economic Strategies ◽

10.33917/es-8.174.2020.136-141 ◽

2020 ◽

Vol 144 ◽

pp. 136-141

Author(s):

Aleksei F. Renkel’ ◽

Keyword(s):

High Risk ◽

Research And Development ◽

Russian Federation ◽

Education System ◽

Patent Law ◽

Risk Area ◽

High Risk Area ◽

Foreign Experience ◽

The Russian Federation

At present the education system in the Russian Federation does not include any program teaching the basics of patent law on inventions, therefore protection of copyright holders in courts is very problematic. The article analyzes foreign experience of patent law on inventions, provides examples of implementing research and development results.

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