scholarly journals What the Phage: A scalable workflow for the identification and analysis of phage sequences

2020 ◽  
Author(s):  
Mike Marquet ◽  
Martin Hölzer ◽  
Mathias W. Pletz ◽  
Adrian Viehweger ◽  
Oliwia Makarewicz ◽  
...  

AbstractPhages are among the most abundant and diverse biological entities on earth. Identification from sequence data is a crucial first step to understand their impact on the environment. A variety of bacteriophage identification tools have been developed over the years. They differ in algorithmic approach, results and ease of use. We, therefore, developed “What the Phage” (WtP), an easy-to-use and parallel multitool approach for phage identification combined with an annotation and classification downstream strategy, thus, supporting the user’s decision-making process when the phage identification tools are not in agreement to each other. WtP is reproducible and scales to thousands of datasets through the use of a workflow manager (Nextflow). WtP is freely available under a GPL-3.0 license (https://github.com/replikation/What_the_Phage).

2018 ◽  
Vol 32 (02) ◽  
pp. 069-074 ◽  
Author(s):  
Kyle Sanniec ◽  
Jourdan Carboy ◽  
James Thornton

AbstractThe authors provide an overview of lip reconstruction after Mohs surgery based on the senior author's practice. Lip reconstruction offers unique challenges to preserve not only lip function but also aesthetics. Lip reconstruction must take into consideration the three anatomical layers that comprise the lip and defects that involve the mucosa, the muscle, the skin or more than one layer will help determine the modality of repair. The authors offer an algorithm based on defect location, tissue involvement, and severity of defect to simplify an often complex decision-making process.


2021 ◽  
Author(s):  
Nnamdi Madichie ◽  
Josephat Sua

<p>The aim of this study was to establish who makes procurement decisions, what resources are used while researching the business buying decision-making process in the procurement of capital medical laboratory equipment (CMLE) in public hospitals. Participants for the study were selected using purposive sampling with a view to providing insights into the explored issues. The target respondents were medical superintendents, medical laboratory technologists and procurement officers in six county referral hospitals in Kenya between May-June 2018. The findings show that medical salespersons, catalogues, and referrals from colleagues were consulted when researching CMLE procurement. Factors considered important in the business decision-making included quality, continuity of reagents supply, supplier capability, equipment costs, and ease of use. Public hospitals in Kenya should adopt participatory purchasing models with key stakeholders such as buyers, lower level employees in hospital departments, and physicians, are included in the buying decision-making.<i> </i><i></i></p>


2020 ◽  
Vol 12 (2) ◽  
pp. 609 ◽  
Author(s):  
Lucia Della Spina ◽  
Francesco Calabrò ◽  
Alessandro Rugolo

The decision-making process relating to Social Housing (SH) policies and projects involves social and urban transformations and is consequently linked to urban planning, urban regeneration projects, the dynamics of the real estate market and cooperation between public and private developers. Furthermore, this decision-making process must be supported by assessments relating to economic feasibility and assessments on social and environmental sustainability. The paper illustrates a decision support evaluation model for the implementation of integrated urban redevelopment programs related to Social Housing interventions to be implemented in PPP. The model is based on the search for an economic balance between the interests of the parties involved, with the aim of maximizing the share of housing in SH by minimizing the public contribution quota. The model was developed on a degraded settlement of Public Residential Construction, the subject of a wider urban regeneration program in the Municipality of Reggio Calabria (Italy). Considering the financial feasibility constraint for the developer and the conditions of the local real estate market, with the risk of the investment attached to it, the model makes it possible to verify the economic sustainability and the financial feasibility of the interventions in SH through the estimation of: (i) The profit of the developer/investor; (ii) the trade-in value to be paid to the developer against the investment; (iii) the maximum share of SH to be carried out in development. The research and the results obtained highlight the utility of the model and the ease of use in the programming phase, in relation to urban regeneration programs that involve interventions in SH.


2021 ◽  
Author(s):  
Nnamdi Madichie ◽  
Josephat Sua

<p>The aim of this study was to establish who makes procurement decisions, what resources are used while researching the business buying decision-making process in the procurement of capital medical laboratory equipment (CMLE) in public hospitals. Participants for the study were selected using purposive sampling with a view to providing insights into the explored issues. The target respondents were medical superintendents, medical laboratory technologists and procurement officers in six county referral hospitals in Kenya between May-June 2018. The findings show that medical salespersons, catalogues, and referrals from colleagues were consulted when researching CMLE procurement. Factors considered important in the business decision-making included quality, continuity of reagents supply, supplier capability, equipment costs, and ease of use. Public hospitals in Kenya should adopt participatory purchasing models with key stakeholders such as buyers, lower level employees in hospital departments, and physicians, are included in the buying decision-making.<i> </i><i></i></p>


Author(s):  
Mayank Singh ◽  
Aparna Acharya

AbstractMale and female pattern hair loss (PHL) is an innocuous condition, but it has a major psychological impact on the sufferer. This paper aims to provide a simple algorithmic approach toward diagnosis, staging, and treatment of PHL in males and females. It also aims at simplifying the decision-making process for the surgeon with regard to timing and extent of procedure for hair transplant surgeries. Various treatment options, their merits and demerits, along with scientific evidence supporting or not supporting the treatment options are discussed in detail.


2014 ◽  
Vol 23 (2) ◽  
pp. 104-111 ◽  
Author(s):  
Mary Ann Abbott ◽  
Debby McBride

The purpose of this article is to outline a decision-making process and highlight which portions of the augmentative and alternative communication (AAC) evaluation process deserve special attention when deciding which features are required for a communication system in order to provide optimal benefit for the user. The clinician then will be able to use a feature-match approach as part of the decision-making process to determine whether mobile technology or a dedicated device is the best choice for communication. The term mobile technology will be used to describe off-the-shelf, commercially available, tablet-style devices like an iPhone®, iPod Touch®, iPad®, and Android® or Windows® tablet.


Sign in / Sign up

Export Citation Format

Share Document