scholarly journals Osteophyte size and location on hip DXA scans are associated with hip pain: findings from a cross sectional study in UK Biobank

2021 ◽  
Author(s):  
Benjamin G Faber ◽  
Raja Ebsim ◽  
Fiona R Saunders ◽  
Monika Frysz ◽  
Claudia Lindner ◽  
...  
Keyword(s):  
Femoral Head ◽  
Joint Space Width ◽  
Hip Osteoarthritis ◽  
Joint Space ◽  
Cross Sectional Study ◽  
Hip Pain ◽  
Uk Biobank ◽  
Cross Sectional ◽  
Automated Method ◽  
The Relationship

Objective It remains unclear how the different features of radiographic hip osteoarthritis (rHOA) contribute to hip pain. We examined the relationship between rHOA, including its individual components, and hip pain using a novel dual-energy x-ray absorptiometry (DXA)-based method. Methods Hip DXAs were obtained from UK Biobank. An automated method was developed to obtain minimum joint space width (mJSW) from points placed around the femoral head and acetabulum. Osteophyte areas at the lateral acetabulum, superior and inferior femoral head were derived manually. Semi-quantitative measures of osteophytes and joint space narrowing (JSN) were combined to provide a measure of rHOA. Logistic regression was used to examine the relationships between these variables and hip pain, obtained via questionnaires. Results 6,807 hip DXAs were examined. rHOA was present in 353 [5.2%] individuals and was associated with hip pain [OR 2.07 (95% CI 1.54-2.80)] and hospital diagnosed OA [5.73 (2.89-11.36)]. Total osteophyte area and mJSW were associated with hip pain [1.29 (1.21-1.36), 0.84 (0.77-0.92) respectively] in unadjusted models. After mutually adjusting and adding demographic covariates, total osteophyte area continued to have strong evidence of association with hip pain [1.31 (1.23-1.39)] but mJSW did not [0.95 (0.87-1.04)]. Acetabular, superior and inferior femoral osteophyte areas were all independently associated with hip pain [1.19 (1.13-1.26), 1.22 (1.15-1.29), 1.21 (1.14-1.28) respectively]. Conclusion The relationship between DXA-derived rHOA and prevalent hip pain is explained by osteophyte area rather than mJSW. Osteophytes at different locations showed important, potentially independent, associations with hip pain, possibly reflecting the contribution of distinct biomechanical pathways.

Influence of the experience of the reader on reliability of joint space width measurement. A cross-sectional multiple reading study in hip osteoarthritis

2011 ◽  
Vol 78 (5) ◽  
pp. 499-505 ◽  
Author(s):  
Paul Ornetti ◽  
Jean-Francis Maillefert ◽  
Simon Paternotte ◽  
Maxime Dougados ◽  
Laure Gossec
Keyword(s):  
Joint Space Width ◽  
Hip Osteoarthritis ◽  
Joint Space ◽  
Cross Sectional ◽  
Width Measurement ◽  
Reading Study ◽  
Space Width

scholarly journals Factors associated with hip pain in end-stage renal disease patients on prevalent hemodialysis: a cross-sectional study

2021 ◽  
Vol 48 (1) ◽  
Author(s):  
Hüma Bölük Şenlikci ◽  
Sevgi İkbali Afşar ◽  
Selin Özen ◽  
Cihat Burak Sayın
Keyword(s):  
Diabetes Mellitus ◽  
Musculoskeletal Disorders ◽  
Short Form ◽  
Hip Osteoarthritis ◽  
Cross Sectional Study ◽  
Hip Pain ◽  
Sectional Study ◽  
Musculoskeletal Problem ◽  
Related Factors ◽  
Cross Sectional

Abstract Background Hemodialysis (HD) patients suffer from musculoskeletal disorders. The most reported musculoskeletal problem is arthralgia. Hip arthralgia has been commonly reported in patients undergoing HD. Hip pain can lead to a decrease in levels of physical activity, limitation in joint range of motion, and consequently difficulties in performing activities of daily living (ADL) and impair the quality of life (QoL). The aim of the study is to reveal the prevalence of hip pain and related factors in HD patients. This cross-sectional study included 73 patients on prevalent HD whose ages ranged from 25 to 65 years and who were on HD for more than 6 months. Physical examination and radiological imaging were done to every patient. Visual analog scale, Barthel Index, and Short Form-36 were used to evaluate pain, ADL, and QoL, respectively. Results Hip arthralgia was detected in 32 patients. Around 43% of which were diagnosed hip osteoarthritis, 34% greater trochanteric pain syndrome, 15% femoroacetabular impingement, and 6% soft tissue calcifications. Diabetes mellitus and hemodialysis duration were found to be significantly different between the groups of hip pain and without hip pain. Diabetes mellitus was identified as an independent risk factor for hip pain in hemodialysis patients. ADL and QoL were significantly lower in patients with hip pain compared to those without (p < 0.01; p < 0.05, respectively). Conclusions The results of our research show that HD patients should be screened for the presence of hip pain and other musculoskeletal disorders and that this is an area which requires further consideration and medical research.

scholarly journals Strategies for increasing gait speed in patients with hip osteoarthritis: their clinical significance and effects on hip loading

2020 ◽  
Author(s):  
Hiroshige Tateuchi ◽  
Haruhiko Akiyama ◽  
Koji Goto ◽  
Kazutaka So ◽  
Yutaka Kuroda ◽  
...  
Keyword(s):  
Physical Function ◽  
Gait Speed ◽  
Stride Length ◽  
Joint Space Width ◽  
Hip Osteoarthritis ◽  
Joint Space ◽  
Hip Pain ◽  
Rate Of Increase ◽  
Type C ◽  
Space Width

Abstract Background: Changes in gait speed are required in various situations and can be achieved by changing stride length, cadence, or both. Differences in strategies for increasing gait speed may have different effects on hip joint and physical function. The purpose of this study was to determine the effects of strategies for increasing gait speed on hip pain, physical function, and changes in hip loading during gait in patients with hip osteoarthritis (OA). We hypothesized that patients who increase gait speed mainly by increasing cadence would have lesser hip pain, a higher physical function, and a lower rate of increase in hip moments with increasing gait speed.Methods: Forty-seven patients with secondary hip OA (age, 48.3 ± 11.0 years) were included. Gait speed, stride length, cadence, and peak and impulse of the hip moments were measured during gait at self-selected normal and fast gait speeds. The patients were classified as types S (with mainly increasing stride length, n = 11 [23.4%]), C (with mainly increasing cadence, n = 23 [48.9%]), and SC (with increasing stride length and cadence, n = 13 [27.7%]) according to whether they used changes in stride length and/or cadence to transition from normal to fast gait. Hip pain, physical function, and hip moments changes during gait were compared between types.Results: The physical function was higher in types C (38.0 ± 8.8, P = 0.018) and SC (40.6 ± 8.5, P = 0.015) than in type S (28.2 ± 7.8), even after adjustment for age and minimum joint space width. Hip pain was not significantly different between types. The robustness of these results was confirmed with sensitivity analysis. The rates of increases in peak external hip adduction (P = 0.003) and internal rotation moments (P = 0.009) were lower in type C than in type SC.Conclusions: Type C tended to suppress the increase in hip moments during fast gait. Types C and SC, which included increased cadence, maintained higher physical function levels than type S. Encouraging the use of cadence-increasing strategy may be useful for reducing hip loading and maintaining physical function in patients with hip OA.

scholarly journals Osteophyte size and location on hip DXA scans are associated with hip pain: findings from a cross sectional study in UK Biobank

Bone ◽  
2021 ◽  
pp. 116146
Author(s):  
Benjamin G. Faber ◽  
Raja Ebsim ◽  
Fiona R. Saunders ◽  
Monika Frysz ◽  
Claudia Lindner ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Hip Pain ◽  
Uk Biobank ◽  
Sectional Study ◽  
Cross Sectional ◽  
Dxa Scans

scholarly journals Strategies for increasing gait speed in patients with hip osteoarthritis: their clinical significance and effects on hip loading

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Hiroshige Tateuchi ◽  
Haruhiko Akiyama ◽  
Koji Goto ◽  
Kazutaka So ◽  
Yutaka Kuroda ◽  
...  
Keyword(s):  
Physical Function ◽  
Gait Speed ◽  
Stride Length ◽  
Joint Space Width ◽  
Hip Osteoarthritis ◽  
Joint Space ◽  
Hip Pain ◽  
Rate Of Increase ◽  
Type C ◽  
Space Width

Abstract Background Changes in gait speed are required in various situations and can be achieved by changing stride length, cadence, or both. Differences in strategies for increasing gait speed may have different effects on hip joint and physical function. The purpose of this study was to determine the effects of strategies for increasing gait speed on hip pain, physical function, and changes in hip loading during gait in patients with hip osteoarthritis (OA). We hypothesized that patients who increase gait speed mainly by increasing cadence would have lesser hip pain, a higher physical function, and a lower rate of increase in hip moments with increasing gait speed. Methods Forty-seven patients with secondary hip OA (age, 48.3 ± 11.0 years) were included. Gait speed, stride length, cadence, and peak and impulse of the hip moments were measured during gait at self-selected normal and fast gait speeds. The patients were classified as types S (with mainly increasing stride length, n = 11 [23.4%]), C (with mainly increasing cadence, n = 23 [48.9%]), and SC (with increasing stride length and cadence, n = 13 [27.7%]) according to whether they used changes in stride length and/or cadence to transition from normal to fast gait. Hip pain, physical function, and hip moment changes during gait were compared between types. Results The physical function was higher in types C (38.0 ± 8.8, P = 0.018) and SC (40.6 ± 8.5, P = 0.015) than in type S (28.2 ± 7.8), even after adjustment for age and minimum joint space width. Hip pain was not significantly different between types. The robustness of these results was confirmed with sensitivity analysis. The rates of increases in peak external hip adduction (P = 0.003) and internal rotation moments (P = 0.009) were lower in type C than in type SC. Conclusions Type C tended to suppress the increase in hip moments during fast gait. Types C and SC, which included increased cadence, maintained higher physical function levels than type S. Encouraging the use of cadence-increasing strategy may be useful for reducing hip loading and maintaining physical function in patients with hip OA.

scholarly journals Strategies for increasing gait speed in patients with hip osteoarthritis: their clinical significance and effects on hip loading

2020 ◽  
Author(s):  
Hiroshige Tateuchi ◽  
Haruhiko Akiyama ◽  
Koji Goto ◽  
Kazutaka So ◽  
Yutaka Kuroda ◽  
...  
Keyword(s):  
Physical Function ◽  
Gait Speed ◽  
Stride Length ◽  
Joint Space Width ◽  
Hip Osteoarthritis ◽  
Joint Space ◽  
Hip Pain ◽  
Rate Of Increase ◽  
Type C ◽  
Space Width

Abstract Background: Changes in gait speed are required in various situations and can be achieved by changing stride length, cadence, or both. Differences in strategies for increasing gait speed may have different effects on hip joint and physical function. The purpose of this study was to determine the effects of strategies for increasing gait speed on hip pain, physical function, and changes in hip loading during gait in patients with hip osteoarthritis (OA). We hypothesized that patients who increase gait speed mainly by increasing cadence would have lesser hip pain, a higher physical function, and a lower rate of increase in hip moments with increasing gait speed.Methods: Forty-seven patients with secondary hip OA (age, 48.3 ± 11.0 years) were included. Gait speed, stride length, cadence, and peak and impulse of the hip moments were measured during gait at self-selected normal and fast gait speeds. The patients were classified as types S (with mainly increasing stride length, n = 11 [23.4%]), C (with mainly increasing cadence, n = 23 [48.9%]), and SC (with increasing stride length and cadence, n = 13 [27.7%]) according to whether they used changes in stride length and/or cadence to transition from normal to fast gait. Hip pain, physical function, and hip moments changes during gait were compared between types.Results: The physical function was higher in types C (38.0 ± 8.8, P = 0.018) and SC (40.6 ± 8.5, P = 0.015) than in type S (28.2 ± 7.8), even after adjustment for age and minimum joint space width. Hip pain was not significantly different between types. The robustness of these results was confirmed with sensitivity analysis. The rates of increases in peak external hip adduction (P = 0.003) and internal rotation moments (P = 0.009) were lower in type C than in type SC.Conclusions: Type C tended to suppress the increase in hip moments during fast gait. Types C and SC, which included increased cadence, maintained higher physical function levels than type S. Encouraging the use of cadence-increasing strategy may be useful for reducing hip loading and maintaining physical function in patients with hip OA.

scholarly journals Strategies for increasing gait speed in patients with hip osteoarthritis: their clinical significance and effects on hip loading

2020 ◽  
Author(s):  
Hiroshige Tateuchi ◽  
Haruhiko Akiyama ◽  
Koji Goto ◽  
Kazutaka So ◽  
Yutaka Kuroda ◽  
...  
Keyword(s):  
Physical Function ◽  
Hip Joint ◽  
Gait Speed ◽  
Stride Length ◽  
Three Dimensional ◽  
Joint Space Width ◽  
Hip Osteoarthritis ◽  
Joint Space ◽  
Hip Pain ◽  
Type C

Abstract Background Change in gait speed is required in various situations in daily life, and can be achieved by changing stride length, cadence, or both. Differences in strategies for increasing gait speed may have different effects on the hip joint and on physical function. Our primary purpose was to determine the effects of strategies for increasing gait speed on hip pain and physical function in patients with hip osteoarthritis (OA). The secondary purpose was to examine the effects of strategies for increasing gait speed on the changes in hip loading during gait. Methods Forty-seven patients with secondary hip OA (age 48.3 ± 11.0 years) were included. Gait speed, stride length, cadence, and peak and impulse of the hip joint moment were measured during gait at self-selected normal and fast gait speeds, using a three-dimensional motion analysis system. The patients were classified as types S (increasing mainly stride length), C (increasing mainly cadence), and SC (increasing stride length and cadence) according to whether they used changes in stride length and/or cadence to transition from a normal to a fast gait. Hip pain, physical function, and change in hip moments during gait were compared between the types. Results The distribution of the patients was as follows: types S, 23.4%; C, 48.9%; and SC, 27.7%. Physical function status was higher in types C (P = 0.018) and SC (P = 0.015) than in type S, even after adjustment for age and minimum joint space width. Hip pain was not significantly different between the types. The robustness of those results was confirmed by a sensitivity analysis. The rates of the increases in peak external hip adduction (P = 0.003) and internal rotation moments (P = 0.009) were lower in type C than in type SC. Conclusions Type C tended to suppress the increase in hip joint moments during fast gait. Types C and SC, which included increased cadence, maintained higher physical function levels than type S. Encouraging use of a cadence-increasing strategy may be useful for reducing hip loading and maintaining physical function in patients with hip OA.

scholarly journals Examining the Relationship between Toxoplasma gondii and Seropositivity and Serointensity and Depression in Adults from the United Kingdom and the United States: A Cross-Sectional Study

Pathogens ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 1101
Author(s):  
Shawn D. Gale ◽  
Lance D. Erickson ◽  
Bruce L. Brown ◽  
Dawson W. Hedges
Keyword(s):  
Toxoplasma Gondii ◽  
The United States ◽  
Cross Sectional Study ◽  
Uk Biobank ◽  
Cross Sectional ◽  
The United Kingdom ◽  
Neuropsychiatric Diseases ◽  
Multiple Regression Modeling ◽  
The Uk ◽  
The Relationship

Infecting approximately one-third of the world’s population, the neurotropic protozoan Toxoplasma gondii has been associated with cognition and several neuropsychiatric diseases including schizophrenia and bipolar disorder. Findings have been mixed, however, about the relationship between Toxoplasma gondii and depression, with some studies reporting positive associations and others finding no associations. To further investigate the association between Toxoplasma gondii and depression, we used data from the UK Biobank and the National Health and Examination Survey (NHANES). Results from adjusted multiple-regression modeling showed no significant associations between Toxoplasma gondii and depression in either the UK Biobank or NHANES datasets. Further, we found no significant interactions between Toxoplasma gondii and age, sex, educational attainment, and income in either dataset that affected the association between Toxoplasma gondii and depression. These results from two community-based datasets suggest that in these samples, Toxoplasma gondii is not associated with depression. Differences between our findings and other findings showing an association between Toxoplasma gondii and depression could be due to several factors including differences in socioeconomic variables, differences in Toxoplasma gondii strain, and use of different covariates in statistical modeling.

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