scholarly journals Short-term effects of BNT162b2 mRNA COVID-19 vaccination on physiological measures: a prospective study

2021 ◽  
Author(s):  
Yftach Gepner ◽  
Merav Mofaz ◽  
Shay Oved ◽  
Matan Yechezkel ◽  
Keren Constantini ◽  
...  
Keyword(s):  
Heart Rate ◽  
Mobile Application ◽  
Systemic Reaction ◽  
Physiological Data ◽  
P Value ◽  
Physiological Measures ◽  
Short Term ◽  
Post Vaccination ◽  
Baseline Levels ◽  
Short Term Effects

Background: Clinical trial guidelines for assessing the safety of vaccines, including the FDA criteria, are primarily based on subjective, self-reported questionnaires. Despite the tremendous technological advances in recent years, objective, continuous assessment of physiological measures post-vaccination is rarely performed. Methods: To evaluate the short-term effects of the BNT162b2 COVID-19 vaccine on physiological measures, we conducted a prospective observational study during the mass vaccination campaign in Israel. 160 individuals >18 years who were not previously found to be COVID-19 positive and who received the second dose of the COVID-19 vaccine between 1 January 2021, and 13 March 2021 were equipped with a chest-patch sensor and a dedicated mobile application. The chest-patch sensor continuously measured 13 physiological vitals one day before the inoculation (baseline), for four days: heart rate, blood oxygen saturation, respiratory rate, systolic and diastolic blood pressure, pulse pressure, mean arterial pressure, heart rate variability, stroke volume, cardiac output, cardiac index, systemic vascular resistance, and body temperature. The mobile application collected daily self-reported questionnaires starting one day before the inoculation, for 15 days on local and systemic reactions, sleep quality, stress levels, physical activity, and mood levels. Findings: Within the first 48 hours post-vaccination, we identified significant changes (p-value <0.05) in nearly all 13 chest-patch indicators compared to their baseline levels. 48.5% (n=78) reported no local or systemic reaction. Nevertheless, we identified considerable changes in chest-patch indicators during the first 48 hours post-vaccination also in this group of presumably asymptomatic participants. Within three days from vaccination, these measures returned to baseline levels in both groups, further supporting the safety of the vaccine. Interpretation: Our work underscores the importance of obtaining objective physiological data in addition to self-reported questionnaires when performing clinical trials, particularly in ones conducted in very short time frames. Funding: The European Research Council (ERC) project #949850.

The impact of noise on the short-term effects of traffic-related air pollution on heart rate variability in young healthy adults

2013 ◽  
Vol 2013 (1) ◽  
pp. 4244
Author(s):  
Jing Huang ◽  
Furong Deng ◽  
Shaowei Wu ◽  
Henry Lu ◽  
Yu Hao ◽  
...  
Keyword(s):  
Heart Rate ◽  
Air Pollution ◽  
Heart Rate Variability ◽  
Healthy Adults ◽  
Short Term ◽  
The Impact ◽  
Short Term Effects

Playing with Violence

2011 ◽  
pp. 271-292
Author(s):  
Patrícia Arriaga ◽  
Augusta Gaspar ◽  
Francisco Esteves
Keyword(s):  
Prosocial Behavior ◽  
Physiological Measures ◽  
Short Term ◽  
Theoretical Approaches ◽  
Short Term Effects

This chapter intends to contribute to the clarification of the controversy surrounding the short-term effects of playing violent games [VG] on aggressive and prosocial behavior, aggressive thoughts, feelings, and physiological measures. An updated review of research on the effects of playing VG on the main variables under analysis is reviewed and some theoretical approaches, as well as methodological concerns, are addressed. Finally, questions that remain unanswered are discussed and future areas of research in this area are suggested.

The Gender Effects of Heart Rate Variability Response during Short-Term Exercise using Stair Stepper from Statistical Analysis

2016 ◽  
Vol 2 (2) ◽  
pp. 359 ◽  
Author(s):  
Nor Aziyatul Izni Mohd Rosli ◽  
Mohd Azizi Abdul Rahman ◽  
Malarvili Balakrishnan ◽  
Takashi Komeda ◽  
Saiful Amri Mazlan ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Gender Effects ◽  
P Value ◽  
Healthy Male ◽  
Short Term ◽  
Male And Female ◽  
Males And Females ◽  
Female Subjects

This study is aimed to explore the Heart Rate Variability (HRV) response during short-term exercise by stair stepper and to compare the finding between young healthy male and female subjects. The responses were statistically analyzed by applying independent-samples t-test statistical method. The calculation of Coefficient of Variation (CoV (%)) and the slope of the linear regression is used to assess the steadiness of the HRV. Furthermore, the results also demonstrated that female subjects had greater significant p-value of RMSSD feature and significance p-value in a LF feature is greater in male. Thus, the ongoing results demonstrated that males have the sympathetic drive and females have predominant parasympathetic drive using short-term exercise by stepper. Thus, the experiment results indicate the suitability of developing rehabilitation devices in the field of Autonomic Nervous System (ANS), research, control system and rehabilitation enginering, which may help to isolate males and females.

Physiological and behavioural responses to short-haul transport by stock trailer in finished steers

2007 ◽  
Vol 87 (3) ◽  
pp. 291-297 ◽  
Author(s):  
M. E. Booth-McLean ◽  
K. S. Schwartzkopf-Genswein ◽  
F. A. Brown ◽  
C. L. Holmes ◽  
A. L. Schaefer ◽  
...  
Keyword(s):  
Heart Rate ◽  
Stress Responses ◽  
Plasma Cortisol ◽  
Time Of Day ◽  
Cortisol Concentration ◽  
Physiological Data ◽  
Short Term ◽  
Plasma Cortisol Concentration ◽  
A Value ◽  
Radio Transmitters

Nineteen British cross-bred steers (623 ± 10.6 kg) were transported in groups of four or five for 3 h and returned to their home pens. Jugular cannulas, heart rate (HR; BPM) monitors and radio transmitters were used to non-invasively collect physiological data. Heart rate (n = 13) was lower during highway travel (83.5 ± 3.15, P > 0.05) compared with pre-loading (118.9 ± 3.19, P < 0.01) and off-loading (97.5 ± 4.47) but was not different from travel in town (88.8 ± 2.90). Plasma cortisol concentration (µg dL-1, n = 16) increased from pre-loading (1.87 ± 0.28) to off-loading (3.10 ± 0.28, P < 0.02) and decreased to 1.16 ± 0.28 µg dL-1 by 1 h after off-loading (P < 0.001), a value not different from pre-loading levels. Body temperature measured at offloading was 0.19°C higher (P < 0.001) than at pre-loading. No differences in the time spent eating and ruminating were observed when compared between a 1-h period 1 d prior to transport and the same time of day post-transport (P > 0.50). Increases in HR (P < 0.01) and lying time (P < 0.001) post-transport compared with the days prior suggest cattle experienced some fatigue. Mild, short-term stress responses were observed in finished steers exposed to 3 h of transportation. Key words: Cortisol, heart rate, hematocrit, behaviour, steers, transportation

scholarly journals Short-Term Effects of Favorite Intakes on Heart Rate Variability

1991 ◽  
Vol 27 (Supplement) ◽  
pp. 266-267
Author(s):  
K. Hirayanagi ◽  
R. Sumioka ◽  
K. Enomoto ◽  
A. Miyamoto ◽  
K. Yajima
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Short Term ◽  
Short Term Effects
Sign in / Sign up

Export Citation Format

Share Document