scholarly journals Interpretable surface-based detection of focal cortical dysplasias: a MELD study

Author(s):  
Hannah Spitzer ◽  
Mathilde Ripart ◽  
Kirstie Whitaker ◽  
Antonio Napolitano ◽  
Luca De Palma ◽  
...  

Introduction: One outstanding challenge for machine learning in diagnostic biomedical imaging is algorithm interpretability. A key application is the identification of subtle epileptogenic focal cortical dysplasias (FCDs) from structural MRI. FCDs are difficult to visualise on structural MRI but are often amenable to surgical resection. We aimed to develop an open-source, interpretable, surface-based machine-learning algorithm to automatically identify FCDs on heterogeneous structural MRI data from epilepsy surgery centres worldwide. Methods: The Multi-centre Epilepsy Lesion Detection (MELD) Project collated and harmonised a retrospective MRI cohort of 1015 participants, 618 patients with focal FCD-related epilepsy and 397 controls, from 22 epilepsy centres worldwide. We created a neural network for FCD detection based on 33 surface-based features. The network was trained and cross-validated on 50% of the total cohort and tested on the remaining 50% as well as on 2 independent test sites. Multidimensional feature analysis and integrated gradient saliencies were used to interrogate network performance. Results: Our pipeline outputs individual patient reports, which identify the location of predicted lesions, alongside their imaging features and relative saliency to the classifier. Overall, after including a border-zone around lesions, the developed MELD FCD surface-based algorithm had a sensitivity of 67% and a specificity of 54% on the withheld test cohort, and a sensitivity of 85% on a restricted subcohort of seizure free patients with FCD type IIB who had T1 and FLAIR MRI data. Conclusions: This multicentre, multinational study with open access protocols and code has developed a robust and interpretable machine-learning algorithm for automated detection of focal cortical dysplasias, giving physicians greater confidence in the identification of subtle MRI lesions.

Author(s):  
Shilpa P Khedkar, Et. al.

Due to advances in the field of internet of things (IoT), the transmission speed become very important and need to be discussed. Doing proper assignment of appropriate channels to the generated traffic in SDN based IoT can affect transmission speed enormously. Software Defined Networking has been evolved as a supporting technology to improve the performance of IoT networks and to increase transmission quality. Different machine learning algorithm can be used for prediction of network traffic and allocation of the channel is done for better assignment. Hence, in this paper CNNs based network traffic prediction and allocation of channel technique is proposed. This technique significantly improves the network performance.


2018 ◽  
Author(s):  
C.H.B. van Niftrik ◽  
F. van der Wouden ◽  
V. Staartjes ◽  
J. Fierstra ◽  
M. Stienen ◽  
...  

Author(s):  
Kunal Parikh ◽  
Tanvi Makadia ◽  
Harshil Patel

Dengue is unquestionably one of the biggest health concerns in India and for many other developing countries. Unfortunately, many people have lost their lives because of it. Every year, approximately 390 million dengue infections occur around the world among which 500,000 people are seriously infected and 25,000 people have died annually. Many factors could cause dengue such as temperature, humidity, precipitation, inadequate public health, and many others. In this paper, we are proposing a method to perform predictive analytics on dengue’s dataset using KNN: a machine-learning algorithm. This analysis would help in the prediction of future cases and we could save the lives of many.


2019 ◽  
Vol XVI (4) ◽  
pp. 95-113
Author(s):  
Muhammad Tariq ◽  
Tahir Mehmood

Accurate detection, classification and mitigation of power quality (PQ) distortive events are of utmost importance for electrical utilities and corporations. An integrated mechanism is proposed in this paper for the identification of PQ distortive events. The proposed features are extracted from the waveforms of the distortive events using modified form of Stockwell’s transform. The categories of the distortive events were determined based on these feature values by applying extreme learning machine as an intelligent classifier. The proposed methodology was tested under the influence of both the noisy and noiseless environments on a database of seven thousand five hundred simulated waveforms of distortive events which classify fifteen types of PQ events such as impulses, interruptions, sags and swells, notches, oscillatory transients, harmonics, and flickering as single stage events with their possible integrations. The results of the analysis indicated satisfactory performance of the proposed method in terms of accuracy in classifying the events in addition to its reduced sensitivity under various noisy environments.


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