scholarly journals Acute and chronic physical activity improve spatial pattern separation in humans

2021 ◽  
Author(s):  
Daniela Ramirez Butavand ◽  
Maria Florencia Rodriguez ◽  
Maria Virginia Cifuentes ◽  
Magdalena Miranda ◽  
Cristian Garcia Bauza ◽  
...  
Keyword(s):  
Physical Activity ◽  
Spatial Pattern ◽  
Pattern Separation ◽  
Long Term Memory ◽  
Virtual Reality Environment ◽  
Spatial Memories ◽  
Spatial Pattern Separation ◽  
Sedentary Subjects ◽  
Over Time

Physical activity benefits both fitness and cognition. However, its effect on long-term memory is unclear. Successful memory involves not only remembering information over time but also keeping memories distinct and less confusing. The ability to separate similar experiences into distinct memories is one of the main features of episodic memory. In this work, we evaluated the effect of acute and chronic physical activity on a new task to assess spatial pattern separation in a 3D virtual reality environment. We manipulated the load of memory similarity and found that 25 minutes of cycling after encoding - but not before retrieval - was sufficient to improve similar, but not dissimilar memories, 24 hours after encoding. Furthermore, we found that participants who engaged in regular physical activity, but not sedentary subjects, showed memory for the similar condition the next day. Thus, physical activity could be a simple way to improve discrimination of spatial memories in humans.

scholarly journals Running enhances spatial pattern separation in mice

2010 ◽  
Vol 107 (5) ◽  
pp. 2367-2372 ◽  
Author(s):  
David J. Creer ◽  
Carola Romberg ◽  
Lisa M. Saksida ◽  
Henriette van Praag ◽  
Timothy J. Bussey
Keyword(s):  
Physical Activity ◽  
Spatial Pattern ◽  
Hippocampal Neurogenesis ◽  
Pattern Separation ◽  
Regular Exercise ◽  
Brain Health ◽  
Voluntary Running ◽  
Spatial Pattern Separation ◽  
Cell Genesis ◽  
Old Mice

Increasing evidence suggests that regular exercise improves brain health and promotes synaptic plasticity and hippocampal neurogenesis. Exercise improves learning, but specific mechanisms of information processing influenced by physical activity are unknown. Here, we report that voluntary running enhanced the ability of adult (3 months old) male C57BL/6 mice to discriminate between the locations of two adjacent identical stimuli. Improved spatial pattern separation in adult runners was tightly correlated with increased neurogenesis. In contrast, very aged (22 months old) mice had impaired spatial discrimination and low basal cell genesis that was refractory to running. These findings suggest that the addition of newly born neurons may bolster dentate gyrus-mediated encoding of fine spatial distinctions.

scholarly journals Spatial pattern separation in cognitively normal young and older adults

Hippocampus ◽  
2012 ◽  
Vol 22 (9) ◽  
pp. 1826-1832 ◽  
Author(s):  
Heather M. Holden ◽  
Calhuei Hoebel ◽  
Kelly Loftis ◽  
Paul E. Gilbert
Keyword(s):  
Older Adults ◽  
Spatial Pattern ◽  
Pattern Separation ◽  
Cognitively Normal ◽  
Spatial Pattern Separation

scholarly journals Individual Differences in Learning Efficiency

2019 ◽  
Vol 28 (6) ◽  
pp. 607-613
Author(s):  
Kathleen B. McDermott ◽  
Christopher L. Zerr
Keyword(s):  
Individual Differences ◽  
Experimental Approach ◽  
Long Term Memory ◽  
Positive Relation ◽  
Future Directions ◽  
Term Memory ◽  
Learning Efficiency ◽  
Rate Of Learning ◽  
Over Time

Most research on long-term memory uses an experimental approach whereby participants are assigned to different conditions, and condition means are the measures of interest. This approach has demonstrated repeatedly that conditions that slow the rate of learning tend to improve later retention. A neglected question is whether aggregate findings at the level of the group (i.e., slower learning tends to improve retention) translate to the level of individual people. We identify a discrepancy whereby—across people—slower learning tends to coincide with poorer memory. The positive relation between learning rate (speed of learning) and retention (amount remembered after a delay) across people is referred to as learning efficiency. A more efficient learner can acquire information faster and remember more of it over time. We discuss potential characteristics of efficient learners and consider future directions for research.

[P1-471]: EFFECT OF ALZHEIMER's DISEASE ON SPATIAL PATTERN SEPARATION

2017 ◽  
Vol 13 (7S_Part_9) ◽  
pp. P469-P470
Author(s):  
Jan Laczó ◽  
Martina Parizkova ◽  
Hana Markova ◽  
Ross Andel ◽  
Martin Vyhnalek ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Spatial Pattern ◽  
Pattern Separation ◽  
Spatial Pattern Separation

The influence of enrichment on spatial pattern separation in zebrafish (Danio rerio)

BIOS ◽  
2020 ◽  
Vol 91 (1) ◽  
pp. 31
Author(s):  
Cairsty DePasquale ◽  
Paul Armstrong ◽  
Xiaosong Li
Keyword(s):  
Spatial Pattern ◽  
Danio Rerio ◽  
Pattern Separation ◽  
Spatial Pattern Separation

scholarly journals Features of subsyndromal and persistent delirium

2012 ◽  
Vol 200 (1) ◽  
pp. 37-44 ◽  
Author(s):  
David Meagher ◽  
Dimitrios Adamis ◽  
Paula Trzepacz ◽  
Maeve Leonard
Keyword(s):  
Rating Scale ◽  
Cognitive Test ◽  
Long Term Memory ◽  
Thought Process ◽  
Diagnostic Features ◽  
Term Memory ◽  
Subsyndromal Delirium ◽  
Short And Long Term ◽  
Over Time

BackgroundLongitudinal studies of delirium phenomenology are lacking.AimsWe studied features that characterise subsyndromal delirium and persistent delirium over time.MethodTwice-weekly evaluations of 100 adults with DSM-IV delirium using the Delirium Rating Scale – Revised-98 (DRS-R98) and Cognitive Test for Delirium (CTD). The generalised estimating equation method identified symptom patterns distinguishing full syndromal from subsyndromal delirium and resolving from persistent delirium.ResultsParticipants (mean age 70.2 years (s.d. = 10.5)) underwent 323 assessments (range 2–9). Full syndromal delirium was significantly more severe than subsyndromal delirium for DRS-R98 thought process abnormalities, delusions, hallucinations, agitation, retardation, orientation, attention, and short- and long-term memory items, and CTD attention, vigilance, orientation and memory. Persistent full syndromal delirium had greater disturbance of DRS-R98 thought process abnormalities, delusions, agitation, orientation, attention, and short- and long-term memory items, and CTD attention, vigilance and orientation.ConclusionsFull syndromal delirium differs from subsyndromal delirium over time by greater severity of many cognitive and non-cognitive symptoms. Persistent delirium involves increasing prominence of recognised core diagnostic features and cognitive impairment.

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