THE RELATIONSHIP OF THE GASTROINTESTINAL TRACT TO ANEMIA

1937 ◽  
Vol 5 (0) ◽  
pp. 414-418 ◽  
Author(s):  
W. B. Castle
1968 ◽  
Vol 59 (4) ◽  
pp. 595-610 ◽  
Author(s):  
U. Goebelsmann ◽  
N. Wiqvist ◽  
E. Diczfalusy

ABSTRACT A combination of 3H-labelled oestriol-3-sulphate-16-glucosiduronate (OE3-3S,16Gl) and 14C-labelled oestriol-16-glucosiduronate (OE3-16Gl) was infused over a 6 hour period to one woman at midpregnancy and to another woman with missed abortion in the 4th month of gestation. The urinary metabolites were isolated and identified. Sixty-four per cent of the 3H- and about 80 % of the 14C-labelled material was excreted in the urine within 24 hours. Some 20 % of the 3H-labelled, but only 2–3 % of the 14C-labelled material recovered was OE3-3S,16Gl. Approximately one half of the 3H-, but less than one-third of the 14C-labelled material was oestriol-3-glucosiduronate (OE3-3Gl). On the other hand, more than two-thirds of the 14C-labelled material, but less than one-third of the 3H-labelled was OE3-16Gl. The urinary elimination of OE3-3S,16Gl was much slower than that of OE3-16Gl and resembled closely the behaviour of oestriol-3-sulphate (OE3-3S) in this respect. The amounts of endogenous OE3-3S,16Gl and OE3-16Gl reaching the circulation each hour were calculated from their urinary excretion and from the relationship of infused and excreted labelled OE3-3S,16Gl and OE3-16Gl. On the basis of these estimates it is concluded that OE3-3S,16Gl is a quantitatively important constituent of pregnancy plasma, but not of pregnancy urine. It is suggested that OE3-3S,16Gl is formed mainly, if not entirely from OE3-16Gl, most probably in the liver and perhaps also in the gastrointestinal tract. A general scheme is presented, describing the over-all metabolism of conjugated oestriol.


2021 ◽  
pp. 112-117
Author(s):  
A.I. Maksymenko

The question of combined lesions of the oral cavity and internal organs occupy a prominent place among the problems of dentistry nowadays. They allow to reflect the genesis of many diseases that manifest themselves in the oral cavity. Aim of the study was to analyze information on the relationship of diseases of oral cavity and various diseases of gastrointestinal tract. Anatomical and physiological proximity, common innervation and humoral regulation leads to the involvement of organs of oral cavity in the pathological process. Catarrhal gingivitis, stomatitis are often caused by deficiency of vitamins of group B. Above-mentioned deficiency is caused, according to many scientists, by the diseases of gastrointestinal tract. And such diseases of the oral cavity as chronic recurrent stomatitis, lichen planus, chronic recurrent herpetic stomatitis, chronic periodontitis depends on the pathology of the digestive tract. Conclusions. Thus, anatomical and physiological characteristics of children, who suffers from chronic gastrointestinal diseases, make us study the clinical manifestations of dental diseases in these patients. Prospects for further research. Further study of the dental status of children with diseases of the gastrointestinal tract is very valuable.


2020 ◽  
Vol 16 (1) ◽  
pp. 22-29
Author(s):  
Irina Galimova ◽  
Irina Usmanova ◽  
Larisa Gerasimova ◽  
Zuhra Hismatullina ◽  
Yigal Granot ◽  
...  

Subject. The results of a comprehensive clinical examination of patients with acid-dependent diseases of the gastrointestinal tract, including an assessment of some features of the clinical manifestations of recurrent aphthalmic afta and dental quality of life parameters, are examined. The goal is to assess the relationship of the clinical manifestations of recurring aphthae of the oral cavity and the dental quality of life in patients with acid-dependent diseases of the gastrointestinal tract. Methodology. A general clinical and dental examination of 125 young people with recurrent aphthae of the oral cavity against acid-dependent diseases of the gastrointestinal tract was performed. The questionnaire method was used to assess the quality of life of the studied groups of patients depending on the nosology and clinical features of the pathology of the oral mucosa. Results. The percentage of patients with recurrent oral aphthae at the time of the clinical dental examination averaged 46.4 % of cases, with acid-dependent gastrointestinal diseases - 33.6%, the number of relapses averaged 2.57 ± 0.23 times a year. Among triggers of recurrent aphthae of the oral cavity, patients at the time of the clinical examination identified the influence of stressful situations (100 %), chronic diseases of the gastrointestinal tract (80 %), and mucosal injuries (33.6 %). Conclusions. The most frequent triggering factors that provoke the clinical features of recurrent aphthae of the oral cavity are some acid-dependent diseases of the gastrointestinal tract in the form of chronic gastritis and duodenitis and chronic pancreatitis against the background of hyperacid secretion of the stomach, and the mucous membrane is a favorite localization of morphological elements (aphthae) in the area of mesial incisors of the front teeth of the upper or lower jaw, the mucous membrane of the upper or lower lip, mucus melting the side surface of the tongue and the buccal mucosa in premolars.


1957 ◽  
Vol 35 (1) ◽  
pp. 983-992
Author(s):  
R. A. Cleghorn ◽  
J. L. A. Fowler

Five male dogs were adrenalectomized and sympathectomized and maintained by adrenocortical extract for periods of weeks to months. Their general behavior did not differ from those subject to adrenalectomy alone, but in three it was observed that the hair grew long and curly. In the other two a lesser change may have been missed. Following withdrawal of the hormone, death occurred rather suddenly in three, and adrenal insufficiency developed sooner in the other two than in dogs only adrenalectomized. Pathological changes in the gastrointestinal tract were qualitatively the same following death after hormone withdrawal in the adrenalectomized–sympathectomized animals and in dogs only adrenalectomized. Blood changes appeared to be no different in the two groups. The urinary changes with respect to water and electrolytes differed in that the sympathectomized group appeared to take in less water and excrete less urine, but to put out more sodium and chloride, in the few days following withdrawal of hormone. These findings are discussed in particular with respect to the relationship of adrenergic function of the sympathetic nervous system and hormones of the adrenal cortex.


Author(s):  
Yu. G. Samoilova ◽  
O. A. Oleynik ◽  
D. A. Kudlay ◽  
E. V. Sagan ◽  
N. S. Denisov

The review summarizes the data of foreign studies on the relationship of the taxonomic diversity of the oral microbiota and changes in its composition with the development of the metabolic syndrome in children with obesity. This information is of scientific interest from the point of view of the search for new targets and possible ways of conservative treatment in order to prevent and treat obesity through maintaining the microflora of the gastrointestinal tract.


1957 ◽  
Vol 35 (11) ◽  
pp. 983-992
Author(s):  
R. A. Cleghorn ◽  
J. L. A. Fowler

Five male dogs were adrenalectomized and sympathectomized and maintained by adrenocortical extract for periods of weeks to months. Their general behavior did not differ from those subject to adrenalectomy alone, but in three it was observed that the hair grew long and curly. In the other two a lesser change may have been missed. Following withdrawal of the hormone, death occurred rather suddenly in three, and adrenal insufficiency developed sooner in the other two than in dogs only adrenalectomized. Pathological changes in the gastrointestinal tract were qualitatively the same following death after hormone withdrawal in the adrenalectomized–sympathectomized animals and in dogs only adrenalectomized. Blood changes appeared to be no different in the two groups. The urinary changes with respect to water and electrolytes differed in that the sympathectomized group appeared to take in less water and excrete less urine, but to put out more sodium and chloride, in the few days following withdrawal of hormone. These findings are discussed in particular with respect to the relationship of adrenergic function of the sympathetic nervous system and hormones of the adrenal cortex.


Sign in / Sign up

Export Citation Format

Share Document