scholarly journals SIGNS OF DISEASES OF THE GASTROINTESTINAL TRACT IN THE ORAL CAVITY OF CHILDREN

2021 ◽  
pp. 112-117
Author(s):  
A.I. Maksymenko
Keyword(s):  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Clinical Manifestations ◽  
Gastrointestinal Diseases ◽  
Pathological Process ◽  
Combined Lesions ◽  
Dental Diseases ◽  
Group B ◽  
Relationship Of ◽  
The Relationship

The question of combined lesions of the oral cavity and internal organs occupy a prominent place among the problems of dentistry nowadays. They allow to reflect the genesis of many diseases that manifest themselves in the oral cavity. Aim of the study was to analyze information on the relationship of diseases of oral cavity and various diseases of gastrointestinal tract. Anatomical and physiological proximity, common innervation and humoral regulation leads to the involvement of organs of oral cavity in the pathological process. Catarrhal gingivitis, stomatitis are often caused by deficiency of vitamins of group B. Above-mentioned deficiency is caused, according to many scientists, by the diseases of gastrointestinal tract. And such diseases of the oral cavity as chronic recurrent stomatitis, lichen planus, chronic recurrent herpetic stomatitis, chronic periodontitis depends on the pathology of the digestive tract. Conclusions. Thus, anatomical and physiological characteristics of children, who suffers from chronic gastrointestinal diseases, make us study the clinical manifestations of dental diseases in these patients. Prospects for further research. Further study of the dental status of children with diseases of the gastrointestinal tract is very valuable.

scholarly journals SOME FEATURES OF THE RELATIONSHIP OF CLINICAL MANIFESTATIONS AND DENTAL INDICATORS OF LIFE QUALITY IN PATIENTS WITH REFRACTIVE ORAL CAVITIES AFTER ACID-RESPECT TERRITORY

2020 ◽  
Vol 16 (1) ◽  
pp. 22-29
Author(s):  
Irina Galimova ◽  
Irina Usmanova ◽  
Larisa Gerasimova ◽  
Zuhra Hismatullina ◽  
Yigal Granot ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Mucous Membrane ◽  
Clinical Features ◽  
Clinical Manifestations ◽  
Dental Examination ◽  
Relationship Of ◽  
The Relationship

Subject. The results of a comprehensive clinical examination of patients with acid-dependent diseases of the gastrointestinal tract, including an assessment of some features of the clinical manifestations of recurrent aphthalmic afta and dental quality of life parameters, are examined. The goal is to assess the relationship of the clinical manifestations of recurring aphthae of the oral cavity and the dental quality of life in patients with acid-dependent diseases of the gastrointestinal tract. Methodology. A general clinical and dental examination of 125 young people with recurrent aphthae of the oral cavity against acid-dependent diseases of the gastrointestinal tract was performed. The questionnaire method was used to assess the quality of life of the studied groups of patients depending on the nosology and clinical features of the pathology of the oral mucosa. Results. The percentage of patients with recurrent oral aphthae at the time of the clinical dental examination averaged 46.4 % of cases, with acid-dependent gastrointestinal diseases - 33.6%, the number of relapses averaged 2.57 ± 0.23 times a year. Among triggers of recurrent aphthae of the oral cavity, patients at the time of the clinical examination identified the influence of stressful situations (100 %), chronic diseases of the gastrointestinal tract (80 %), and mucosal injuries (33.6 %). Conclusions. The most frequent triggering factors that provoke the clinical features of recurrent aphthae of the oral cavity are some acid-dependent diseases of the gastrointestinal tract in the form of chronic gastritis and duodenitis and chronic pancreatitis against the background of hyperacid secretion of the stomach, and the mucous membrane is a favorite localization of morphological elements (aphthae) in the area of mesial incisors of the front teeth of the upper or lower jaw, the mucous membrane of the upper or lower lip, mucus melting the side surface of the tongue and the buccal mucosa in premolars.

scholarly journals DIAGNOSTIC SIGNIFICANCE OF SOME REPRESENTATIVES OF NORMAL MICROBIOME OF THE ORAL CAVITY IN THE DEVELOPMENT OF RECOVERABLE ACTS OF THE ORAL CAVITY IN PATIENTS WITH ACID-DEPENDENT GASTROINTESTINAL DISEASES

2020 ◽  
Vol 15 (4) ◽  
pp. 31-37
Author(s):  
Irina Galimova ◽  
Irina Usmanova ◽  
Larisa Gerasimova ◽  
Marsel Tuigunov ◽  
Yigal Granot ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Clinical Manifestations ◽  
Gastrointestinal Diseases ◽  
Control Group ◽  
Candida Spp ◽  
Diagnostic Significance ◽  
Detection Frequency ◽  
Enterococcus Spp ◽  
Staphylococcus Spp

Subject. The results of a comprehensive microbiological study of the state of the normobioma of the oral cavity in individuals with recurrent aphthae of the oral cavity against the background of acid-dependent diseases of the gastrointestinal tract are considered. The goal is to determine the diagnostic significance of individual representatives of the oral normobioma in patients with recurrent aphthae of the oral cavity against the background of acid-dependent diseases of the gastrointestinal tract. Methodology. The study involved 83 patients who were divided into two main and control groups depending on the clinical manifestations of recurrent aphthae of the oral cavity on the background of hypersecretory syndrome. Results. The results of the study showed that in patients of the first and second main groups, in which the manifestations of recurrent aphthae in the oral cavity were accompanied by diseases of the gastrointestinal tract with hypersecretory syndrome, the frequency of allocation of staphylococcal flora was 1.3—1.5 times higher compared to control (p≤0.05), an increase in the proportion of S. aureus — 2.5 times. The detection frequency of S. epidermidis in the control and both clinical groups was 28.0, 27.6 and 31.0 % of cases, respectively, the proportion of hemolytic forms in the control group was 4.0 %, in the first 10.3 % (an increase of 2 5 times), in the second — 17.2 % (4.3 times). The observed changes in the species composition may indicate dysbiosis in the oral cavity, caused not only by the presence of recurrent aphthae, but also by acid-dependent diseases of the gastrointestinal tract. Conclusions. In recurrent aphthae of the oral cavity in patients with acid-dependent diseases of the gastrointestinal tract in the microbiome of the oral cavity against the background of reduced titers of lactobacilli, an increase in representatives of Staphylococcus spp., Enterococcus spp is most often observed. and Candida spp. (1.2 times average), Enterococcus spp. (1.4 times), Staphylococcus spp. and Enterobacteriaceae spp. (1.2 times), Actinobacillus spp. (1.1 times).

INTERACTION BETWEEN A FAMILY DOCTOR AND A DENTIST AT AN EARLY STAGE IN THE PREVENTION OF DISEASES OF THE GASTROINTESTINAL TRACT

2021 ◽  
Vol 2 (12(81)) ◽  
pp. 39-43
Author(s):  
M. Ibragimov ◽  
Y. Heydarova ◽  
A. Alizade ◽  
L. Ibragimova
Keyword(s):  
Gastrointestinal Tract ◽  
Oral Cavity ◽  
Early Stage ◽  
Family Doctor ◽  
Scientific Article ◽  
Oral Manifestations ◽  
Family Doctors ◽  
Long Period ◽  
Initial Stage ◽  
The Relationship

This scientific article discusses the oral manifestations of diseases of the gastrointestinal tract. This problem is relevant both for dentists and family doctors. In medicine, for a long period of time, the relationship between diseases affecting the gastrointestinal tract and their symptoms manifested in the oral cavity has been considered. Many scientists and physicians have dealt with this problem, their several opinions are presented in this article. There is a hypothesis among researchers that the oral cavity is a mirror in which all human diseases can be visible. In the oral cavity, most of the alterations occurring in the organism are manifested, due to which, with an attentive attitude to oral manifestations, the disease can be detected already at the initial stage.

scholarly journals Genome-wide variations of SARS-CoV-2 infer evolution relationship and transmission route

2020 ◽  
Author(s):  
Lehai Zhang ◽  
Shifu Wang ◽  
Qian Ren ◽  
Junjie Yang ◽  
Yanqin Lu ◽  
...  
Keyword(s):  
Molecular Detection ◽  
Detection Efficiency ◽  
Evolutionary Relationship ◽  
Clinical Manifestations ◽  
Coding Region ◽  
Gene Coding ◽  
Genome Wide ◽  
Group A ◽  
Group B ◽  
Relationship Of

AbstractIn the epidemic evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the issues of mutation, origin, typing and the effect of mutation on molecular detection remain to be unrevealed. In order to identify the evolutionary relationship of SARS-CoV-2 and evaluate the detection efficiency of primers that are currently used in different countries, we retrieved genomic sequences of 373 SARS-CoV-2 strains from multiple databases and performed genome-wide variation analysis. According to the nucleotide C28144T variation, the SARS-CoV-2 can be divided into group A (117 strains) and group B (256 strains). The spike protein gene (S gene) coding region 1841 (total 23403) A1841G, formed a B1 subgroup (40 strains) in group B, of which 30 strains were from European and American countries in March (especially Washington, USA). These mutations are likely to be influenced by the environment or the immunization selection pressure of different populations. Although the mutation is not in the receptor binding region (RBD) and alkaline cleavage region, it may also affect the ability of transmission and pathogenicity; however, the significance is not yet clear. As the ratio of A / B strains in the epidemic months showed an increasing trend (0.35: 1 in January, 0.62: 1 in February and 0.76: 1 in March), it seems that the transmissibility of group A strains becomes stronger with time. Based on the variation of 11 nucleotide sites during the epidemic process, it is speculated that the Washington strain is more like an ancestor type, and the Wuhan strain is the offspring of the group A virus strain. By comparing the detection capabilities of primers in different countries, the SARS-CoV-2 nucleotide variation may only affect molecular detection of very few strains. The differences in the transmissibility, pathogenicity and clinical manifestations of different types of strains require further investigations.

SYSTEMIC LUPUS ERYTHEMATOSUS AND SYNDROMES POSSIBLY RELATED

PEDIATRICS ◽  
1957 ◽  
Vol 19 (6) ◽  
pp. 1109-1123
Author(s):  
M. A. Ogryzlo ◽  
H. A. Smythe
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Serum Proteins ◽  
Clinical Manifestations ◽  
Electrophoretic Pattern ◽  
Chemotherapeutic Agents ◽  
Systemic Lupus ◽  
Relationship Of ◽  
The Relationship

Attention is drawn to the difficulties that may be encountered in the positive identification and classification of many patients suspected of suffering from systemic lupus erythematosus. Much of this is due to a lack of specific criteria, either clinical or pathologic, for the diagnosis of the disease. The problem has been made more difficult by the recognition of a number of other syndromes that bear a superficial resemblance to systemic lupus erythematosus, yet differ in clinical manifestations, natural course, prognosis and other respects. A feature common to the group is the presence of the L.E. cell phenomenon. The related conditions differ from lupus enythematosus in that the L.E. phenomenon may only be demonstrable intermittently especially during severe exacerbations of the disease, while at the same time disturbances in the electrophoretic pattern of the serum proteins may be much more profound. In systemic rheumatoid disease the prognosis without steroid therapy is better than in systemic lupus erythematosus, although the morbidity may be great. The reactions which follow administration of certain chemotherapeutic agents are of considerable interest, particularly in view of the similarity to lupus erythematosus and rheumatoid arthritis, and the reversibility on withdrawal of the offending agent. The relationship of these syndromes to each other and to classical systemic lupus erythematosus has not yet been resolved, and inclusion of them under the diagnosis of systemic lupus erythematosus at this time must be regarded as premature.

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