A brief review of the essentials of Asymptotic Safety and the Renormalization Group (RG) improvement of the Schwarzschild Black Hole that removes the r = 0 singularity is presented. It is followed with a RG-improvement of the Kantowski-Sachs metric associated with a Schwarzschild black hole interior and such that there is no singularity at t = 0 due to the running Newtonian coupling G(t) (vanishing at t = 0). Two temporal horizons at t _- \simeq t_P and t_+ \simeq t_H are found. For times below the Planck scale t < t_P, and above the Hubble time t > t_H, the components of the Kantowski-Sachs metric exhibit a key sign change, so the roles of the spatial z and temporal t coordinates are exchanged, and one recovers a repulsive inflationary de Sitter-like core around z = 0, and a Schwarzschild-like metric in the exterior region z > R_H = 2G_o M. The inclusion of a running cosmological constant \Lambda (t) follows. We proceed with the study of a dilaton-gravity (scalar-tensor theory) system within the context of Weyl's geometry that permits to single out the expression for the classical potential V (\phi ) = \kappa\phi^4, instead of being introduced by hand, and find a family of metric solutions which are conformally equivalent to the (Anti) de Sitter metric. To conclude, an ansatz for the truncated effective average action of ordinary dilaton-gravity in Riemannian geometry is introduced, and a RG-improved Cosmology based on the Friedmann-Lemaitre-Robertson-Walker (FLRW) metric is explored.