scholarly journals Measurement of the gain volume in amplifying and scattering media by a two-beam spatial-correlation method

2001 ◽  
Vol 63 (3) ◽  
Author(s):  
Tetsu Ito ◽  
Makoto Tomita
2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Chi-Li Chiu ◽  
Michelle A. Digman ◽  
Enrico Gratton

Extracellular matrix (ECM) remodeling is a critical step of many biological and pathological processes. However, most of the studies to date lack a quantitative method to measure ECM remodeling at a scale comparable to cell size. Here, we applied image spatial correlation to collagen second harmonic generation (SHG) images to quantitatively evaluate the degree of collagen remodeling by cells. We propose a simple statistical method based on spatial correlation functions to determine the size of high collagen density area around cells. We applied our method to measure collagen remodeling by two breast cancer cell lines (MDA-MB-231 and MCF-7), which display different degrees of invasiveness, and a fibroblast cell line (NIH/3T3). We found distinct collagen compaction levels of these three cell lines by applying the spatial correlation method, indicating different collagen remodeling ability. Furthermore, we quantitatively measured the effect of Latrunculin B and Marimastat on MDA-MB-231 cell line collagen remodeling ability and showed that significant collagen compaction level decreases with these treatments.


2019 ◽  
Vol 69 (11-12) ◽  
pp. 1273-1285 ◽  
Author(s):  
Laura Brakenhoff ◽  
Gerben Ruessink ◽  
Maarten van der Vegt

Abstract Saw-tooth bars are shore-oblique sand bars that are found along most ebb-tidal deltas of the Frisian Wadden Islands. Although they might significantly affect sediment transport pathways and volumes on the deltas, their general characteristics and dynamics are largely unknown. The main aim of this paper is to determine the typical saw-tooth bar heights, wave lengths, widths, orientations, migration rates and depths of occurrence. To this end, we analysed bathymetries from the Dutch and German Frisian Wadden Islands between 1970 and 2015. Bar heights range between 0.5 and 2 m, and wave lengths range between 300 and 900 m, with an average of 670 m, and the bar crests have a down contour orientation of approximately 25°. The bars are between 800 and 2200 m wide. Saw-tooth bars are located at depths from 3 to 12 m, depending on the slope of the area. Migration speeds of up to 112 m/year were found, using a spatial correlation method. Bar height and migration speed are positively linearly correlated, as well as bar wave length and bar width, bar height and the orientation of the depth contours and migration speed and the orientation of the area. The derived characteristics are compared to those of other bar types to evaluate hypotheses regarding the formation mechanism of the bars.


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