High frequency of HBV in HIV-infected prisoners in Mozambique

2019 ◽  
Vol 15 (1) ◽  
pp. 58-65
Author(s):  
Angelo Augusto ◽  
Orvalho Augusto ◽  
Atija Taquibo ◽  
Carina Nhachigule ◽  
Narcisa Siyawadya ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
High Frequency ◽  
Design Methodology ◽  
Content Type ◽  
B Virus ◽  
First Time ◽  
Hiv Seropositive

Purpose The purpose of this paper is to determine the prevalence of hepatitis B virus (HBV) among 448 HIV-infected prisoners from 32 prisons in Mozambique. Design/methodology/approach All HIV seropositive prisoners were screened for HBV. Findings Of the 448 HIV seropositive prisoners, 51 (11.4 percent, 95%CI: 9.3–13.9 percent) were HBsAg-positive and was significantly higher in prisoners aged<25 years. Originality/value Data from this study show for the first time that the frequency of HBV among HIV-infected prisoners is high, suggesting that immediate interventions are needed during incarceration.

scholarly journals Epidemiology of hepatitis B virus infection in first-time blood donors in the southwestern region of Goiás, central Brazil

2010 ◽  
Vol 33 (1) ◽  
pp. 38-42 ◽  
Author(s):  
Giulena Rosa Leite Cardoso dos Anjos ◽  
Regina Maria Bringel Martins ◽  
Megmar Aparecida dos Santos Carneiro ◽  
Sandra Maria Brunini ◽  
Sheila Araujo Teles
Keyword(s):  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Virus Infection ◽  
Central Brazil ◽  
B Virus ◽  
First Time

High frequency of hepatitis B virus infection in patients with beta-thalassemia receiving multiple transfusions

Vox Sanguinis ◽  
2003 ◽  
Vol 84 (4) ◽  
pp. 292-299 ◽  
Author(s):  
H. Singh ◽  
M. Pradhan ◽  
R. L. Singh ◽  
S. Phadke ◽  
S. R. Naik ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
High Frequency ◽  
Beta Thalassemia ◽  
Hepatitis B Virus Infection ◽  
B Virus

scholarly journals Identification of Hepatitis B virus putative intergenotype recombinants by using fragment typing

2006 ◽  
Vol 87 (8) ◽  
pp. 2203-2215 ◽  
Author(s):  
Jie Yang ◽  
Ke Xing ◽  
Riqiang Deng ◽  
Jinwen Wang ◽  
Xunzhang Wang
Keyword(s):  
Phylogenetic Analysis ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Hot Spots ◽  
Phylogenetic Analyses ◽  
The Other ◽  
Consensus Sequences ◽  
B Virus ◽  
First Time ◽  
Recombination Breakpoints

Eight hundred and thirty-seven human Hepatitis B virus (HBV) genomes were categorized into pure genotypes and potential intergenotypes, according to their fragment types which were determined based on similarity and phylogenetic analyses of 13 contrived fragments of 250 bp against the corresponding fragments of the consensus sequences of genotypes A–H. Twenty-five intergenotypes, including 171 genomes, were revealed from the potential intergenotype recombinants by phylogenetic analysis of the precisely derived mosaic fragments. Among these, four new intergenotypes were discovered. Many genomes were revealed as putative intergenotype recombinants for the first time. About 87 % of the putative recombinants were B/C (120) and A/D (29) hybrids. The other recombinants comprised A/B/C, A/C, A/E, A/G, C/D, C/F, C/G, C/U (U for unknown genotype) and B/C/U hybrids. Genotypes A and C showed a higher recombination tendency than did other genotypes. The results also demonstrated region priority and breakpoint hot spots in the intergenotype recombination. Recombination breakpoints were found to be concentrated mainly in the vicinity of the DR1 region (nt 1640–1900), the pre S1/S2 region (nt 3150–100), the 3′-end of the C gene (nt 2330–2450) and the 3′-end of the S gene (nt 650–830). These results support the suggestion that intergenotype recombinants may result from co-infection with different genotypes.

scholarly journals Epidemiology of hepatitis B virus infection in first-time blood donors in the southwestern region of Goiás, central Brazil

2010 ◽  
Vol 33 (1) ◽  
pp. 38-42
Author(s):  
Giulena Rosa Leite Cardoso dos Anjos ◽  
Regina Maria Bringel Martins ◽  
Megmar Aparecida dos Santos Carneiro ◽  
Sandra Maria Brunini ◽  
Sheila Araujo Teles
Keyword(s):  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Virus Infection ◽  
Central Brazil ◽  
B Virus ◽  
First Time

scholarly journals Role of GSPT1 and GSPT2 polymorphisms in different outcomes upon Hepatitis B virus infection and prognosis to lamivudine therapy

2019 ◽  
Vol 39 (3) ◽  
Author(s):  
Wenxuan Liu ◽  
Ning Ma ◽  
Xia Gao ◽  
Wencong Liu ◽  
Jinhai Jia ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Lamivudine Therapy ◽  
Single Nucleotide ◽  
Tumor Susceptibility ◽  
B Virus ◽  
First Time

Abstract Purpose. ERF3, having been found expressing differently in liver tissues in our previous work, including eRF3a and eRF3b, which are structural homologs named GSPT1 and GSPT2. Recent studies have indicated that eRF3b involved in the development and proliferation of HepG2 cell, and eRF3a may be associated with tumor susceptibility. Based on this, we tested the effects of GSPT1 and GSPT2 single-nucleotide polymorphisms for all major Hepatitis B virus (HBV) outcomes and lamivudine (LAM) treatment in Han Chinese. Method. A total of 1649 samples were enrolled, and peripheral blood samples were collected in the present study. The single-nucleotide polymorphisms in the GSPT1 and GSPT2 region were genotyped using MALDI-TOF MS. Results. Our study demonstrated there was no obvious relevance of either GSPT1-rs33635 or GSPT2-rs974285 polymorphisms with HBV susceptibility, spontaneous recovery, and development of HBV-related diseases. However, we showed for the first time to our knowledge that GSPT1-rs33635C was a predictor for LAM therapy (viral response: odds ratio (OR) = 2.436, P=0.022; biochemical response: OR = 3.328, P=1.73 × 10−4). Conclusions. These findings might provide potential implications for therapeutic guidance.

The Management of Health Care Workers' Accidental Parenteral Exposures to Biological Specimens of HIV Seropositive Individuals

1987 ◽  
Vol 8 (5) ◽  
pp. 211-214 ◽  
Author(s):  
Thomas L. Kuhls ◽  
James D. Cherry
Keyword(s):  
Health Care ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Hiv Infection ◽  
Health Care Workers ◽  
Cross Sectional ◽  
Care Workers ◽  
B Virus ◽  
Immunodeficiency Virus ◽  
Hiv Seropositive

Because of the similarities in the spread of hepatitis B virus and the human immunodeficiency virus (HIV), health officials have been concerned about the acquisition of HIV infection by health care workers. This concern has led to numerous cross-sectional and prospective cohort studies during the last 3 years to evaluate the risks involved. The risk of occupationally acquired HIV infection has been shown to be considerably less than that of hepatitis B virus infection, however needlestick transmission has occurred.

scholarly journals Detection of Highly Prevalent Hepatitis B Virus Coinfection among HIV-Seropositive Persons in Ghana

2010 ◽  
Vol 48 (9) ◽  
pp. 3223-3230 ◽  
Author(s):  
A. M. Geretti ◽  
M. Patel ◽  
F. S. Sarfo ◽  
D. Chadwick ◽  
J. Verheyen ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
B Virus ◽  
Hiv Seropositive

scholarly journals Chimeric Derivatives of Hepatitis B Virus Core Particles Carrying Major Epitopes of the Rubella Virus E1 Glycoprotein

2013 ◽  
Vol 20 (11) ◽  
pp. 1719-1728 ◽  
Author(s):  
Dace Skrastina ◽  
Ivars Petrovskis ◽  
Rasa Petraityte ◽  
Irina Sominskaya ◽  
Velta Ose ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Rubella Virus ◽  
Scattering Data ◽  
Content Type ◽  
Antigenic Activity ◽  
Virus Core ◽  
E1 Protein ◽  
Virus Like Particle ◽  
B Virus

ABSTRACTThree variants of the major rubella virus (RV) E1 protein virus-neutralizing epitope from position 214 to 285 were exposed on the hepatitis B virus (HBV) C-terminally truncated core (HBcΔ) in a virus-like particle (VLP) vector and were produced inEscherichia coli. All three chimeras demonstrated VLPs in bacterial cell lysates, but only HBcΔ-E1(245-285) demonstrated the correct VLP structure after purification. The other chimeras, HBcΔ-E1(214-285) and HBcΔ-E1(214-240), appeared after purification as non-VLP aggregates of 100 to 900 nm in diameter according to dynamic light scattering data. All three variants possessed the intrinsic antigenic activity of RV E1, since they were recognized by natural human anti-RV E1 antibodies and induced an anti-RV E1 response in mice. HBcΔ-E1(214-240) and HBcΔ-E1(245-285) can be regarded as prototypes for a putative RV vaccine because they were able to induce antibodies recognizing natural RV E1 protein in RV diagnostic kits.

First-time use of bevacizumab for aggressive, metastatic hepatocellular carcinoma in an HIV/hepatitis B virus coinfected patient: a case report

2008 ◽  
Vol 20 (5) ◽  
pp. 472-473 ◽  
Author(s):  
Ioannis G. Baraboutis ◽  
Vassilios Papastamopoulos ◽  
Georgios Charitsis ◽  
Lazaros J. Lekakis ◽  
Michael M. Vaslamatzis ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Case Report ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Time Use ◽  
B Virus ◽  
Metastatic Hepatocellular Carcinoma ◽  
Coinfected Patient ◽  
First Time

scholarly journals MOLECULAR BIOLOGY OF HEPATITIS B VIRUS AND IMMUNOPATHOGENESIS OF CHRONIC VIRAL HEPATITIS B

2016 ◽  
pp. 119-126 ◽  
Author(s):  
I. P. Balmasova ◽  
R. I. Sepiashvili ◽  
E. S. Malova
Keyword(s):  
Immune System ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
High Frequency ◽  
Viral Proteins ◽  
Chronic Viral Hepatitis ◽  
Human Immune System ◽  
B Virus ◽  
Viral Hepatitis B ◽  
Human Immune

Hronic hepatitis B belongs to a category of socially significant diseases due to its wide abundance in the world and high frequency of unfavourable outcomes of this disease. Features of interaction of hepatitis B virus with human immune system, accompanying development of mechanisms of escape from immunological control, is the basis of development of chronic hepatitis B. Molecular-biological features of hepatitis B virus are the basis of the indicated mechanisms, and the content of this review is their examination. Herewith, stages of immunopathogenesis of this disease is the basis of characteristics of interaction of viral proteins with cells of immune system, and isolation of those is accepted in contemporary foreign literature.

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