scholarly journals The barriers and facilitators of radical innovation implementation in secondary healthcare: a systematic review

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Salina V. Thijssen ◽  
Maria J.G. Jacobs ◽  
Rachelle R. Swart ◽  
Luca Heising ◽  
Carol X.J. Ou ◽  
...  
Keyword(s):  
Systematic Review ◽  
Radical Innovation ◽  
Barriers And Facilitators ◽  
Added Value ◽  
Innovation Implementation ◽  
Level Of Evidence ◽  
Content Type ◽  
Radical Innovations ◽  
University Of Oxford ◽  
High Level

PurposeThis study aimed to identify the barriers and facilitators related to the implementation of radical innovations in secondary healthcare.Design/methodology/approachA systematic review was conducted and presented in accordance with a PRISMA flowchart. The databases PubMed and Web of Science were searched for original publications in English between the 1st of January 2010 and 6th of November 2020. The level of radicalness was determined based on five characteristics of radical innovations. The level of evidence was classified according to the level of evidence scale of the University of Oxford. The Consolidated Framework for Implementation Research was used as a framework to classify the barriers and facilitators.FindingsBased on the inclusion and exclusion criteria, nine publications were included, concerning six technological, two organizational and one treatment innovation. The main barriers for radical innovation implementation in secondary healthcare were lack of human, material and financial resources, and lack of integration and organizational readiness. The main facilitators included a supportive culture, sufficient training, education and knowledge, and recognition of the expected added value.Originality/valueTo our knowledge, this is the first systematic review examining the barriers and facilitators of radical innovation implementation in secondary healthcare. To ease radical innovation implementation, alternative performance systems may be helpful, including the following prerequisites: (1) Money, (2) Added value, (3) Timely knowledge and integration, (4) Culture, and (5) Human resources (MATCH). This study highlights the need for more high-level evidence studies in this area.

The impact of intellectual capital and knowledge flows on incremental and radical innovation

2018 ◽  
Vol 10 (2/3) ◽  
pp. 149-170 ◽  
Author(s):  
Duy Quoc Nguyen
Keyword(s):  
Social Capital ◽  
Human Capital ◽  
Intellectual Capital ◽  
Radical Innovation ◽  
Knowledge Flows ◽  
Innovation Performance ◽  
Incremental Innovation ◽  
Content Type ◽  
Radical Innovations ◽  
The Impact

PurposeThe purpose of this paper is to develop a theoretical and empirical exploration of link between organization intellectual capital and knowledge flows with its incremental and radical innovation performance.Design/methodology/approachThis paper adopts relevant literature of social capital and organizational learning to examine the impact of intellectual capital and knowledge flows on incremental and radical innovation based on surveying 95 firms. To test the research hypotheses, regression analysis is used.FindingsResults of the study show that human capital and top-down knowledge flows significantly and positively influence both incremental and radical innovations. Social capital and bottom-up knowledge flows do not have any significant impact on incremental or/and radical innovation. Organizational capital has a positive impact on incremental innovation as expected.Practical implicationsThe results offer several practical implications for business managers to harvest its knowledge bases resident in the firm’s different forms appropriately to make innovation successful. Particularly, knowledge resident in human capital and organizational capital is useful for making incremental innovation. Especially, new knowledge, new skills and new perspectives resident in human capital are crucial important for making radical innovation. Both incremental and radical innovations are positively influenced by dynamic managerial capabilities.Originality/valueThis study contributes to literature by providing new evidence linking organization intellectual capital and knowledge flows with its innovation performance. Especially, the missing link between top-down knowledge flows and radical innovation is empirically examined. Value of this study is that social capital and bottom-up knowledge flows are not universally beneficial for enhancing innovation and their impacts on innovation performance are context dependent and more sophisticated than it is recognized in the literature.

The power of balance: interplay effects of exploitative leadership style, work–family balance and family-friendly workplace practices on innovation implementation

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Grazia Garlatti Costa ◽  
Darija Aleksić ◽  
Guido Bortoluzzi
Keyword(s):  
Leadership Style ◽  
Curvilinear Relationship ◽  
Innovation Implementation ◽  
Content Type ◽  
Family Balance ◽  
Family Friendly ◽  
Work Family Balance ◽  
Workplace Practices ◽  
Work Family ◽  
High Level

PurposeThe purpose of this paper is to investigate the inverted U-shaped relationship that exists between exploitative leadership styles and innovation implementation. In addition, drawing on the social cognitive theory, the paper explores the effect of the three-way interaction between exploitative leadership style (ELS), work–family balance (WFB) and family-friendly workplace practices (FFWPs) on innovation implementation.Design/methodology/approachA quantitative study of 440 employees from 38 medium and large companies based in Italy and Croatia was conducted, using an online survey. The proposed hypotheses were tested using hierarchical regression analysis.FindingsThe results show that there is an inverted U-shaped curvilinear relationship between ELS and innovation implementation. Furthermore, the findings support the existence of the three-way interaction suggesting that the combination of high-level WFB and high-level FFWPs strengthens the relationship between ELS² and innovation implementation.Originality/valueThis is the first contribution that examines a curvilinear relationship between ELS and innovation implementation. Additionally, it contributes to the work–family literature by providing the first empirical examination of the joint impact of WFB and FFWPs in enhancing innovation implementation. Our results suggest that individuals who perceive a high level of WFB and who work in an organization with family-friendly practices are more accepting of an exploitative leader, and that the positive feelings from the family domain encourage the implementation of innovation. These results may change the attitudes of managers, encouraging them to consider WFB and FFWPs as important for the implementation of innovation.

Unstimulated high-sensitive thyroglobulin is a powerful prognostic predictor in patients with thyroid cancer

2019 ◽  
Vol 58 (1) ◽  
pp. 130-137 ◽  
Author(s):  
Luca Giovanella ◽  
Marco Castellana ◽  
Pierpaolo Trimboli
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Differentiated Thyroid Carcinoma ◽  
Level Of Evidence ◽  
Prognostic Performance ◽  
Clinical Scenarios ◽  
High Level ◽  
Operating Points

Abstract Background Differentiated thyroid carcinoma (DTC) has an excellent prognosis and the role of high-sensitive thyroglobulin measured during levothyroxine (ON-T4 hs-Tg) testing to discriminate patients with structural from not-evidence of disease (SED and NED, respectively) has been investigated. We conducted a systematic review and meta-analysis evaluating the performance of ON-T4 hs-Tg in two clinical scenarios considering its negative predictive value (NPV) as primary outcome: (1) diagnostic performance of Tg when undetectable value and NED status are simultaneously demonstrated; (2) prognostic performance of undetectable Tg in predicting NED in the subsequent follow-up. Methods This systematic review and meta-analysis were registered on PROSPERO (CRD42019125092). PubMed, Scopus, CENTRAL and Web of Science were searched until February 12, 2019. Original articles reporting data on SED/NED in patients with detectable/undetectable ON-T4 hs-Tg were selected. Summary operating points were estimated using a random-effects model. Results Out of 1413 retrieved papers, 10 studies evaluating 1796 patients were included. Participants were outpatients diagnosed with DTC, treated with near-total (NTx) or total thyroidectomy (TTx) with or without radioactive iodine (RAI). The NPV of ON-T4 hs-Tg for diagnostic and prognostic performance was 99.4% (95% CI 98.9–99.9; I2 = 13%) and 99.4% (95% CI 98.8–100; I2 = 0%), respectively. Conclusions Our findings show that ON-T4 hs-Tg is an excellent diagnostic tool and prognostic factor to rule-out SED. A high level of evidence is provided to decrease the intensity and frequency of follow-up in those DTC patients having undetectable high-sensitive Tg.

The experience of conducting a Cochrane systematic review of the impact of clinical pathways on professional practice, patient outcomes, length of stay and hospital costs

2009 ◽  
Vol 13 (2) ◽  
pp. 62-66 ◽  
Author(s):  
Thomas Rotter ◽  
Leigh Kinsman ◽  
Erica James ◽  
Andreas Machotta ◽  
Holger Gothe ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Pathways ◽  
Hospital Costs ◽  
Evidence Base ◽  
Care Group ◽  
Level Of Evidence ◽  
Organisation Of Care ◽  
High Level ◽  
Meta Analyses ◽  
The Impact

Despite the high prevalence of clinical pathways (CPWs), the results from published studies are inconsistent and contradictory. The plethora of study designs, settings and lack of an agreed definition of a CPW make the relevance of individual studies difficult to apply to clinical settings. It was timely to catalogue and analyse the existing evidence base for CPWs via a rigorous systematic review. Systematic reviews and meta-analyses provide a high level of evidence for the effectiveness of interventions and are commonly employed reviewing strategies for addressing scientific questions in health-related research. This method is especially useful when research results are known to be inconsistent. Instead of conducting another primary evaluation, a detailed review is needed that reflects a summation of available research. This paper reports and discusses methodological and technical issues of a systematic review of the effectiveness of CPWs in hospitals, based on our experience with the Cochrane Effective Practice and Organisation of Care Group.

The effect of network structure on radical innovation in living labs

2016 ◽  
Vol 31 (6) ◽  
pp. 743-757 ◽  
Author(s):  
Seppo Leminen ◽  
Anna-Greta Nyström ◽  
Mika Westerlund ◽  
Mika J. Kortelainen
Keyword(s):  
Network Structure ◽  
Radical Innovation ◽  
Incremental Innovation ◽  
Network Structures ◽  
Content Type ◽  
Radical Innovations ◽  
Strategic Objective ◽  
Living Lab ◽  
Multiplex Network ◽  
Living Labs

Purpose This study aims to focus on living labs as a means of achieving radical innovation by discussing the differences in their network structure and its effect on the type of innovation outcome. Design/methodology/approach This research analyses 24 living labs in four countries using qualitative methods. Findings A specific network structure referred to as a distributed multiplex supports radical innovation in living labs, while distributed and centralized network structures support incremental innovations. Also, the results suggest that radical innovation depends on the driving actor and objectives in a living lab. Research limitations/implications A bias on the perceived novelty of innovation may exist when analyzing data collected through interviews with a limited number of living lab participants compared to a large number of informants. This study proposes a two-dimensional framework based on the network structure to investigate innovation in living labs. Practical implications This paper offers a classification tool to identify, categorize and make sense of organizations’ participation in open innovation networks and in living labs. Originality/value The study provides evidence that, although the distributed multiplex network structure supports the emergence of radical innovations, the distributed and centralized network structures support incremental innovation. A combination of a provider- or utilizer-driven living lab and a distributed multiplex network structure, with a clearly defined and future-oriented strategic objective, offers good potential for radical innovation to occur.

scholarly journals Salvage of the Failed Total Wrist Arthroplasty: A Systematic Review

2020 ◽  
Vol 09 (05) ◽  
pp. 446-456
Author(s):  
Onur Berber ◽  
Sam Gidwani ◽  
Lorenzo Garagnani ◽  
Michelle Spiteri ◽  
Nicholas Riley ◽  
...  
Keyword(s):  
Systematic Review ◽  
Revision Surgery ◽  
Revision Arthroplasty ◽  
Postoperative Outcome ◽  
Secondary Outcome ◽  
Level Of Evidence ◽  
Total Wrist Arthroplasty ◽  
High Level ◽  
Meta Analyses ◽  
Wrist Arthroplasty

Abstract Background Although the performance of total wrist arthroplasty systems has improved, failure is encountered and is a major challenge to manage. Questions Does physical function improve with surgical management of the failed wrist arthroplasty? Is there an improvement in secondary outcome measures including pain, grip strength, and range of motion? What are the reasons for failure in primary total wrist arthroplasty? What are the complications associated with revision of the failed total wrist arthroplasty? What are the survival profiles of the different revision strategies? Methods A systematic review of available literature was performed. Studies were systematically assessed, and data extracted from suitable studies for review. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines were adhered to. The study protocol was modified from a previous protocol published on the PROSPERO database. Results Fourteen studies were identified considering 218 patients/214 index operations with a follow-up duration following revision surgery of 2 months to 21 years (silicone wrist arthroplasty—42 cases; nonsilicone wrist arthroplasty—172 cases). The functional outcome of revision surgery was infrequently recorded and documented with only short-term assessments undertaken. Complications were seen in 1:2 revision procedures, with re-revision surgeries required in 21.6% of revised primary nonsilicone arthroplasties. Re-revision rate following a revision arthrodesis was 21.4% (15/70 cases) compared with revision arthroplasty of 34.8% (32/92 cases). Revision arthrodesis nonunion rate was 17.5% (22 cases). Conclusion This review has confirmed the high level of surgical complexity and the likelihood of a complicated postoperative outcome when salvaging a failed wrist replacement. Level of Evidence This is a Level 3, systematic review study.

scholarly journals Evaluación de la superficie del esmalte luego de la descementación de brackets metálicos. Revisión sistemática / Enamel Surface Assessment after Metallic Bracket Debonding. A Systematic Review

2018 ◽  
Vol 36 (77) ◽  
Author(s):  
Nicolás Arboleda Ariza ◽  
Isaac Wasserman Milhem ◽  
Diana Katherina Reina Velosa ◽  
Ingrid Quintero Quinche
Keyword(s):  
Systematic Review ◽  
High Speed ◽  
Control Group ◽  
Level Of Evidence ◽  
Double Blind ◽  
Adhesive Resin ◽  
Published Evidence ◽  
Revisión Sistemática ◽  
High Level ◽  
Surface Assessment

RESUMEN. Antecedentes: A través del tiempo se han propuesto diferentes técnicas para realizar la remoción del adhesivo y resina remanentes luego de retirar los brackets, pero no existe un consenso entre los diferentes autores. Objetivo: el propósito de esta revisión sistemática fue identificar cuál es la técnica más adecuada para evitar injuria al esmalte durante la remoción de la resina remanente después de retirados los brackets. Métodos: Esta revisión sistemática se basó en los lineamientos de PRISMA, Para recolectar la evidencia publicada se realizó una búsqueda electrónica en diferentes bases de datos. Resultados: Se encontraron 8 artículos con una evidencia media (> de 9) los cuales fueron considerados en esta revisión sistemática. Al parecer la remoción de resina y adhesivo remanentes con ultrasonido, fresa de carburo de tungsteno de alta velocidad y piedras blancas generan la mayor pérdida de esmalte, mientras que 6 artículos proponen la fresa de tungsteno de baja velocidad como la mejor técnica. Conclusiones: Se requieren estudios aleatorizados, con grupo control, doble-ciego y una técnica de análisis del esmalte estandarizada para poder generar un nivel de evidencia alto y dar recomendaciones más acertadas para el clínico.ABSTRACT. Background: Over time different techniques have been proposed for the removal of the remaining adhesive and resin after the removal of brackets, but there is no consensus among authors. Objective: Evaluate the most appropriate technique to prevent injury to the enamel during the removal of the remaining resin after the brackets are removed. Methods: This systematic review is based on the guidelines of PRISMA, to collect the published evidence there was a various electronic databases search. Results: There were only 8 items with medium evidence (> 9) which were considered in this systematic review. Apparently removing remaining adhesive resin with ultrasound, tungsten carbide cutter high speed and white stones generate the greatest loss of enamel, while 6 articles propose the tungsten bur at low speed as the best technique. Conclusions: Randomized studies with control group, double-blind and a standardized technique of enamel analysis are required to generate a high level of evidence and give more accurate recommendations for clinicians.

scholarly journals Chinese Herbal Medicine Combined with Conventional Therapy for Blood Pressure Variability in Hypertension Patients: A Systematic Review of Randomized Controlled Trials

2015 ◽  
Vol 2015 ◽  
pp. 1-16 ◽  
Author(s):  
Zhuo Chen ◽  
Liqiong Wang ◽  
Guoyan Yang ◽  
Hao Xu ◽  
Jianping Liu
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Chinese Medicine ◽  
Conventional Therapy ◽  
Blood Pressure Variability ◽  
Randomized Clinical Trials ◽  
Data Extraction ◽  
Level Of Evidence ◽  
Beneficial Effects ◽  
High Level

Objective. The aim of this systematic review is to evaluate effect of Chinese medicine combined with conventional therapy on blood pressure variability (BPV) in hypertension patients.Methods. All randomized clinical trials (RCTs) comparing Chinese medicine with no intervention or placebo on the basis of conventional therapy were included. Data extraction, analyses, and quality assessment were performed according to the Cochrane standards.Results. We included 13 RCTs and assessed risk of bias for all the trials. Chinese medicine has a significant effect in lowering blood pressure (BP), reducing BPV in the form of standard deviation (SD) or coefficient of variability (CV), improving nighttime BP decreased rate, and reversing abnormal rhythm of BP.Conclusions. Chinese medicine was safe and showed beneficial effects on BPV in hypertension patients. However, more rigorous trials with high quality are warranted to give high level of evidence before recommending Chinese medicine as an alternative or complementary medicine to improve BPV in hypertension patients.

scholarly journals Effectiveness of nursing interventions in preventing and treating radiotherapy side effects in cancer patients: a systematic review

2021 ◽  
Vol 55 ◽  
Author(s):  
Aline Moraes de Abreu ◽  
Duan Renato da Silva Fraga ◽  
Bruna Bastos Giergowicz ◽  
Rosália Borges Figueiró ◽  
Roberta Waterkemper
Keyword(s):  
Systematic Review ◽  
Side Effects ◽  
Oral Care ◽  
Nursing Interventions ◽  
Patient Centered ◽  
Level Of Evidence ◽  
Centered Care ◽  
Recommendation Grade ◽  
High Level

ABSTRACT Objective: To synthesize the best available evidence on the effectiveness of nursing interventions in radiotherapy patient care and to summarize the evidence on the experience and acceptability of interventions reported by health professionals involved in the prevention and treatment of side effects. Method: A mixed-method systematic review. Quantitative and qualitative studies are presented. Results: Twelve studies published between 2013 and 2017 were included. Most interventions found focused on skin care, oral care, nausea and vomiting and nursing consultation. In accordance with high level of evidence and recommendation grade of the studies, the use of Calendula officinalis and thyme honey were considered effective for preventing and treating radiodermatitis and mucositis, respectively. Conclusion: The quality of evidence of nursing interventions is weak. Although there are studies with a strong design and a high level of evidence, publication of nursing interventions is not enough and does not present a high quality to support practice to plan an effective patient-centered care.

Migration, diaspora and development: impressions from India

2018 ◽  
Vol 12 (4) ◽  
pp. 472-487
Author(s):  
Nishikant Singh ◽  
Priyanka Koiri
Keyword(s):  
Systematic Review ◽  
Conceptual Framework ◽  
Domain Knowledge ◽  
Wide Spectrum ◽  
Relevant Literature ◽  
Influential Factors ◽  
Special Focus ◽  
Content Type ◽  
High Level ◽  
Positive Impacts

PurposeThe purpose of this paper is to provide a conceptual overview of potential diasporic influence in India by Indian diaspora and to outline a wide spectrum of policy interventions for better utilisation of diasporic resources, which are under-exploited.Design/methodology/approachThis paper used a systematic review approach to analyze the vast empirical and theoretical literature, up to 2016, and to assess the different kinds of impacts of diaspora on the homeland. A list of top-tier journals in the field of international migration, diaspora and ethnic entrepreneurship was compiled. From there, each and every paper was identified, examined, coded and classified into high-level themes. These were then reviewed, analyzed and interpreted.FindingsIndian diasporic affair has undergone numerous changes since India’s independence. This study presents a conceptual framework on the role of migration and diaspora in the country of origin with a special focus on India and point out the possible directions for future studies.Research limitations/implicationsThe systematic review approach has a qualitative nature, in which the relevant literature was interpreted based on the authors’ domain knowledge and expertise.Practical implicationsAcademicians and policy practitioners can gain a comprehensive understanding of the dynamic relationships among the key influential factors in migration, diaspora and its developmental role in homeland, as presented in the conceptual framework in the study. Accordingly, policymakers will be able to develop effective strategies to leverage the positive impacts of diasporic role in India and the other South-Asian developing countries.Originality/valueThis systematic review synthesizes the findings reported in most recent publications and government reports and develops an integrated conceptual framework, anchoring on possible positive impacts of diaspora in homeland. This framework provides a visual diagram to practitioners for a better understanding of the relevant literature and assists researchers and policymakers in developing a new strategy for future diasporic affairs.

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