UK vote reinforces long-term political realignment

2021 ◽  
Keyword(s):  
United Kingdom ◽  
Content Type ◽  
Political Realignment

Headline UNITED KINGDOM: Election reflects behavioural shifts

UK industrial strategy is crucial to long-term growth

2017 ◽  
Keyword(s):  
United Kingdom ◽  
Content Type

Headline UNITED KINGDOM: Industrial strategy is key to growth

'Brexit' could hinder long-term UK growth

2016 ◽  
Keyword(s):  
At Risk ◽  
United Kingdom ◽  
Trading Partner ◽  
Content Type ◽  
The United Kingdom ◽  
Scottish Independence ◽  
The City

Significance Depending on the outcome, the United Kingdom's relation with its largest trading partner may be at risk, together with the City of London's role as a financial hub and the ability of EU citizens to work freely in the United Kingdom. Impacts In the event of Brexit, the pound could fall to 1.3 against the dollar and towards parity against the euro. Despite having sold off already, UK bank stocks could fall further in the case of Brexit. Given Scotland's pro-EU stance, an 'out' vote could reopen the debate about Scottish independence.

China will largely abide by Hong Kong handover terms

2017 ◽  
Keyword(s):  
Hong Kong ◽  
United Kingdom ◽  
Young People ◽  
Political Repression ◽  
Content Type ◽  
The United Kingdom ◽  
Uk Government ◽  
The Uk ◽  
The City

Significance This case adds to a growing list of incidents, including the abduction of five Hong Kong booksellers by mainland agents in 2015, that feed fears in Hong Kong that Beijing is undermining the autonomy the city was promised when the UK government handed it over to China in 1997. Impacts The United Kingdom is unlikely to escalate disputes over Beijing's adherence to the handover treaty since doing so might backfire. Evidence of China interfering with business in Hong Kong would be far more economically damaging than targeted political repression. Even limited encroachments by Beijing will increase pessimism about the city's long-term future and make young people keener to emigrate.

FDI is unlikely to return to Turkey's mid-2000s peak

2017 ◽  
Keyword(s):  
United Kingdom ◽  
Content Type ◽  
High Profile ◽  
The Past ◽  
Business Operations ◽  
The United Kingdom ◽  
Political Uncertainties

Subject Turkey’s failure to attract and retain FDI. Significance Turkey has long failed to match its peers in attracting outside investment, which peaked in 2007; there is no sign of any return to that level. More worryingly, in the past two years, a number of high-profile investors have announced plans to leave. Other investors are privately expressing growing concern at seizures of companies and assets belonging to people alleged to be connected to the July 2016 failed coup, and at the strength of government anti-Western rhetoric. Impacts The level of FDI in manufacturing and business operations is likely to remain stagnant. Investors will be wary of committing to a country where they are unsure of their welcome over the long term. Political uncertainties in the United Kingdom, France, Germany and over the direction of US policy will affect Turkey’s main sources of FDI.

Norway's defence focus will shift to the High North

2016 ◽  
Keyword(s):  
United Kingdom ◽  
Armed Forces ◽  
Strategic Orientation ◽  
Content Type ◽  
The United Kingdom ◽  
Defence Spending ◽  
Defence Policy

Subject Norway's defence policy. Significance The 'Long-Term Plan for the Norwegian Armed Forces for the Years 2017-2020', released on June 17, sets the tone for Oslo's current and future defence policy. It announces a significant spending increase dedicated primarily to procuring key capabilities. It also solidifies Norway's strategic orientation to the High North, a process which has been under way for some time after a decade of expeditionary operations in places such as Afghanistan. Impacts The plan will support increasing cooperation among NATO's northern members, including the United Kingdom, Denmark, Iceland and Canada. A greater focus on the High North may further strain NATO's relations with Russia. Norway's increased defence spending may raise US pressure on other NATO countries to do the same.

New Brexit deal would damage UK-EU trade relations

2019 ◽  
Keyword(s):  
United Kingdom ◽  
Economic Impact ◽  
Content Type ◽  
Trade Relations ◽  
Playing Field ◽  
The United Kingdom ◽  
Defence Cooperation ◽  
The Uk ◽  
Regulatory Flexibility

Subject Economic impact of Brexit. Significance The latest Brexit deal differs significantly from that agreed by former Prime Minister Theresa May. The United Kingdom (except for Northern Ireland) will leave the EU’s customs territory. Moreover, if the UK government refuses to sign up to “level playing field” provisions, any future EU-UK trade deal is likely to be considerably more limited in scope. As a result, the long-term economic impact of Brexit will be greater. Impacts The key issue concerning trade talks is the extent to which London is prepared to accept constraints on its future regulatory flexibility. Substantial regulatory divergence could damage future UK-EU security and defence cooperation. It is possible that the United Kingdom will leave the EU at the end of 2020 without a trade deal in place.

Dual-isotope single-photon emission computerized tomography scanning in patients with glioblastoma multiforme: association with patient survival and histopathological characteristics of tumor after high-dose radiotherapy

1998 ◽  
Vol 89 (1) ◽  
pp. 60-68 ◽  
Author(s):  
Richard B. Schwartz ◽  
B. Leonard Holman ◽  
Joseph F. Polak ◽  
Basem M. Garada ◽  
Marc S. Schwartz ◽  
...  
Keyword(s):  
Survival Rate ◽  
Glioblastoma Multiforme ◽  
Single Photon ◽  
Photon Emission ◽  
High Dose ◽  
Term Survival ◽  
Content Type ◽  
Dual Isotope ◽  
Fine Print

Object. The study was conducted to determine the association between dual-isotope single-photon emission computerized tomography (SPECT) scanning and histopathological findings of tumor recurrence and survival in patients treated with high-dose radiotherapy for glioblastoma multiforme. Methods. Studies in which SPECT with 201Tl and 99mTc-hexamethypropyleneamine oxime (HMPAO) were used were performed 1 day before reoperation in 47 patients with glioblastoma multiforme who had previously been treated by surgery and high-dose radiotherapy. Maximum uptake of 201Tl in the lesion was expressed as a ratio to that in the contralateral scalp, and uptake of 99mTc-HMPAO was expressed as a ratio to that in the cerebellar cortex. Patients were stratified into groups based on the maximum radioisotope uptake values in their tumor beds. The significance of differences in patient gender, histological characteristics of tissue at reoperation, and SPECT uptake group with respect to 1-year survival was elucidated by using the chi-square statistic. Comparisons of patient ages and time to tumor recurrence as functions of 1-year survival were made using the t-test. Survival data at 1 year were presented according to the Kaplan—Meier method, and the significance of potential differences was evaluated using the log-rank method. The effects of different variables (tumor type, time to recurrence, and SPECT grouping) on long-term survival were evaluated using Cox proportional models that controlled for age and gender. All patients in Group I (201Tl ratio < 2 and 99mTc-HMPAO ratio < 0.5) showed radiation changes in their biopsy specimens: they had an 83.3% 1-year survival rate. Group II patients (201T1 ratio < 2 and 99mTc-HMPAO ratio of ≥ 0.5 or 201Tl ratio between 2 and 3.5 regardless of 99mTc-HMPAO ratio) had predominantly infiltrating tumor (66.6%); they had a 29.2% 1-year survival rate. Almost all of the patients in Group III (201Tl ratio > 3.5 and 99mTc-HMPAO ratio ≥ 0.5) had solid tumor (88.2%) and they had a 6.7% 1-year survival rate. Histological data were associated with 1-year survival (p < 0.01); however, SPECT grouping was more closely associated with 1-year survival (p < 0.001) and was the only variable significantly associated with long-term survival (p < 0.005). Conclusions. Dual-isotope SPECT data correlate with histopathological findings made at reoperation and with survival in patients with malignant gliomas after surgical and high-dose radiation therapy.

Long-term management of patients with multiple brain metastases after shaped beam radiosurgery

2004 ◽  
pp. 406-412
Author(s):  
Paul Okunieff ◽  
Michael C. Schell ◽  
Russell Ruo ◽  
E. Ronald Hale ◽  
Walter G. O'Dell ◽  
...  
Keyword(s):  
Brain Metastases ◽  
Tumor Control ◽  
Content Type ◽  
Negative Results ◽  
Multiple Metastases ◽  
Extracranial Disease ◽  
Successful Control ◽  
The Brain

✓ The role of radiosurgery in the treatment of patients with advanced-stage metastatic disease is currently under debate. Previous randomized studies have not consistently supported the use of radiosurgery to treat patients with numbers of brain metastases. In negative-results studies, however, intracranial tumor control was high but extracranial disease progressed; thus, patient survival was not greatly affected, although neurocognitive function was generally maintained until death. Because the future promises improved systemic (extracranial) therapy, the successful control of brain disease is that much more crucial. Thus, for selected patients with multiple metastases to the brain who remain in good neurological condition, aggressive lesion-targeting radiosurgery should be very useful. Although a major limitation to success of this therapy is the lack of control of extracranial disease in most patients, it is clear that well-designed, aggressive treatment substantially decreases the progression of brain metastases and also improves neurocognitive survival. The authors present the management and a methodology for rational treatment of a patient with breast cancer who has harbored 24 brain metastases during a 3-year period.

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