MediVol: An initial Study into Real-Time, Interactive 3D Visualisation of Soft Tissue Pathologies

2008 ◽  
Author(s):  
Rob Aspin ◽  
Matt Smith ◽  
Charles Hutchinson ◽  
Len Funk
Keyword(s):  
Soft Tissue ◽  
Real Time ◽  
Initial Study ◽  
3D Visualisation ◽  
Interactive 3D

A study of real-time simulation of liver of virtual surgical robot based on biologically position-based dynamic model

2021 ◽  
pp. 1-16
Author(s):  
Dan Luo ◽  
Yu Zhang ◽  
Jia Li ◽  
Jisheng Li
Keyword(s):  
Soft Tissue ◽  
Real Time ◽  
Surgical Instruments ◽  
Organic Polymer ◽  
Tetrahedral Mesh ◽  
Virtual Surgery ◽  
Constraint Force ◽  
Real Time Simulation ◽  
Time Simulation ◽  
Spring Force

Virtual surgery robot can accurately modeling of surgical instruments and human organs, and realistic simulation of various surgical phenomena such as deformation of organic tissues, surgery simulation system can provide operators with reusable virtual training and simulation environment. To meet the requirement of virtual surgery robot for the authenticity and real-time of soft tissue deformation and surgical simulation in liver surgery, a new method is proposed to simulate the deformation of soft tissue. This method combines the spring force, the external force of the system, and the constraint force produced by the constraint function of the position-based dynamics. Based on the position-based dynamics, an improved three-parameter mass-spring model is added. In the calculation of the elastic force, the nonlinearity and viscoelasticity of the soft tissue are introduced, and the joint force of the constraint projection process and the constraint force of the position-based dynamics is used to modify mass points movement. The method of position-based dynamics based on biological characteristics, not only considers the biomechanical properties of biological soft tissue as an organic polymer such as viscoelasticity, nonlinearity, and incompressibility but also retains the rapidity and stability of the position based dynamic method. Through the simulation data, the optimal side length of tetrahedral mesh in the improved three-parameter model is obtained, and the physical properties of the model are proved. The real-time simulation of the liver and other organs is completed by using the Geomagic touch force feedback device, which proves the practicability and effectiveness of this method.

Quadratic Corotated Finite Elements for Real-Time Soft Tissue Registration

2012 ◽  
pp. 39-50 ◽  
Author(s):  
Stefan Suwelack ◽  
Sebastian Röhl ◽  
Rüdiger Dillmann ◽  
Anna-Laura Wekerle ◽  
Hannes Kenngott ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Finite Elements ◽  
Real Time

The Framework for Real-Time Simulation of Deformable Soft-Tissue Using a Hybrid Elastic Model

2006 ◽  
pp. 75-83 ◽  
Author(s):  
Shaoting Zhang ◽  
Lixu Gu ◽  
Weiming Liang ◽  
Pengfei Huang ◽  
Jan Boehm ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Real Time ◽  
Elastic Model ◽  
Real Time Simulation ◽  
Time Simulation

scholarly journals The metabolomic scent of cancer disease progression in soft tissue sarcoma: A case report

2019 ◽  
Vol 34 (2) ◽  
pp. 205-209 ◽  
Author(s):  
Gianmaria Miolo ◽  
Debora Basile ◽  
Andrea Carretta ◽  
Davide Adriano Santeufemia ◽  
Agostino Steffan ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Disease Progression ◽  
Real Time ◽  
Time Analysis ◽  
Cancer Disease ◽  
Non Invasive ◽  
Real Time Analysis ◽  
Volatile Organic

Background: The purpose of this case report is to describe the potential that metabolomics breath analysis may have in cancer disease monitoring. The advances in mass spectrometry instrumentation allow the accurate real-time analysis of volatile metabolites exhaled in the breath. The application of such non-invasive devices may provide innovative and complementary monitoring of the physio-pathological conditions of cancer patients. Case presentation: A 59-year-old Caucasian woman with spindle cell malignant mesenchymal sarcoma of the presacral region started a first-line therapy with non-pegylated liposomal doxorubicin and ifosfamide associated with pelvic radiant treatment. After two cycles of chemotherapy plus radiotherapy, a significant pulmonary disease progression was reported. Thus, a second-line therapy with trabectedin was administered. However, after only two cycles of treatment a re-staging computed tomography scan reported further cancer disease progression of the target pulmonary lesions as well as occurrence of new satellite bilateral nodules. Real-time analysis of breath exhaled volatile organic compounds, performed by select ion flow tube mass spectrometry (SIFT-MS) during the follow-up of the patient, showed a specific metabolic pattern not observed in the breath of other soft tissue sarcoma patients who achieved clinical benefit from the treatments. Conclusions: This case report revealed the importance of the non-invasive real-time volatile organic compounds breath analysis to distinguish individual specific chemo-resistance phenotypes among soft tissue sarcoma patients. Such observation seems to suggest that breath metabolomics may be particularly useful for monitoring cancer disease progression in soft tissue sarcoma patients where only cost-effective diagnostic tools, such as positron emission tomography and computed tomography, are available.

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