scholarly journals Microfluidic device for continuous magnetophoretic separation of red blood cells

Author(s):  
Ciprian lliescu ◽  
Elena Barbarini ◽  
Marioara Avram ◽  
Guolin Xu ◽  
Andrei Avram
Transfusion ◽  
2020 ◽  
Vol 60 (5) ◽  
pp. 1032-1041
Author(s):  
Jonathan Robidoux ◽  
Audrey Laforce‐Lavoie ◽  
Steve J. Charette ◽  
Sergey S. Shevkoplyas ◽  
Tatsuro Yoshida ◽  
...  

2010 ◽  
Vol 1217 (11) ◽  
pp. 1862-1866 ◽  
Author(s):  
Daniel Lee ◽  
Ponnusamy Sukumar ◽  
Aniza Mahyuddin ◽  
Mahesh Choolani ◽  
Guolin Xu

2014 ◽  
Vol 8 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Vera Faustino ◽  
Diana Pinho ◽  
Tomoko Yaginuma ◽  
Ricardo C. Calhelha ◽  
Isabel C.F.R. Ferreira ◽  
...  

2020 ◽  
Vol 90 (9) ◽  
pp. 1553
Author(s):  
Е.А. Скверчинская ◽  
О.Д. Тапинова ◽  
Н.А. Филатов ◽  
Н.А. Беседина ◽  
И.В. Миндукшев ◽  
...  

To investigate the influence of oxidative stress on red blood cells (RBCs) transport in microvessels and capillaries of the blood microcirculation system, we studied their migration in narrow microchannels in a microfluidic device. We measured cells' velocities in the microchannels under the oxidative stress induced by tert-Butyl hydroperoxide at different concentrations and compared the results with a cytological evaluation of the cell membrane transformations. Oxidative stress caused changes in cells’ shape and volume, travelling velocity of the cells decreased and occlusions of microchannels occurred. The developed microfluidic device provided an ability to study microreology of RBCs under the action of hydroperoxide. In the future, such microfluidic analysis may be used to determine the changes in microrheology of RBCs from patients under the influence of xenobiotics.


Author(s):  
Waqas Waheed ◽  
Anas Alazzam ◽  
Bobby Mathew ◽  
Eiyad Abu Nada ◽  
Ashraf N. Al Khateeb

In this paper, we have introduced a negative Dielectrophoresis based microfluidic system using a novel arrangement of microelectrodes to perform switching of micro objects. Both the experimental and numerical results are presented. Two sets of interdigitated electrodes, extending slightly into the microchannel from each sidewall, are embedded on the bottom of the microchannel. A finite element model in COMSOL Multiphysics 5.2a was developed to demonstrate switching of Red Blood Cells in the microchannel followed by multiple parametric studies to study the effect of several parameters on cell trajectories and optimize the design parameters. To verify numerical results, a PDMS-based microfluidic device on glass wafer was fabricated. The switching of Red Blood Cells in the microfluidic device with a single inlet and three outlets was also demonstrated.


Author(s):  
Arianna Mencattini ◽  
Davide Di Giuseppe ◽  
Michele D'Orazio ◽  
Valeria Rizzuto ◽  
M. M. Manu Pereira ◽  
...  

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