Toward Developing Robust Myotonic Dystrophy Brain Biomarkers using White Matter Tract Profiles Sub-Band Energy and A Framework of Ensemble Predictive Learning

Author(s):  
Tahereh Kamali ◽  
Dana Parker ◽  
John W. Day ◽  
Jacinda Sampson ◽  
Gayle K. Deutsch ◽  
...  
2021 ◽  
Author(s):  
Kesshi M. Jordan ◽  
Michael Lauricella ◽  
Abigail E. Licata ◽  
Simone Sacco ◽  
Carlo Asteggiano ◽  
...  

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Konstantinos Poulakis ◽  
Robert I Reid ◽  
Scott A Przybelski ◽  
David S Knopman ◽  
Jonathan Graff-Radford ◽  
...  

Abstract Deterioration in white-matter health plays a role in cognitive ageing. Our goal was to discern heterogeneity of white-matter tract vulnerability in ageing using longitudinal imaging data (two to five imaging and cognitive assessments per participant) from a population-based sample of 553 elderly participants (age ≥60 years). We found that different clusters (healthy white matter, fast white-matter decliners and intermediate white-matter group) were heterogeneous in the spatial distribution of white-matter integrity, systemic health and cognitive trajectories. White-matter health of specific tracts (genu of corpus callosum, posterior corona radiata and anterior internal capsule) informed about cluster assignments. Not surprisingly, brain amyloidosis was not significantly different between clusters. Clusters had differential white-matter tract vulnerability to ageing (commissural fibres > association/brainstem fibres). Identification of vulnerable white-matter tracts is a valuable approach to assessing risk for cognitive decline.


2011 ◽  
Vol 9 (3) ◽  
pp. 93-93
Author(s):  
Eelco van Duinkerken ◽  
Petra J.W. Pouwels ◽  
Richard G. IJzerman ◽  
Frederik Barkhof ◽  
Martin Klein ◽  
...  

2017 ◽  
Vol 34 (2) ◽  
pp. 291-299 ◽  
Author(s):  
Juan J. Herrera ◽  
Kurt Bockhorst ◽  
Shakuntala Kondraganti ◽  
Laura Stertz ◽  
João Quevedo ◽  
...  

Author(s):  
Eline F. Roelofs ◽  
Janna Marie Bas-Hoogendam ◽  
Steven J. A. van der Werff ◽  
Saskia D. Valstar ◽  
Nic J. A. van der Wee ◽  
...  

2019 ◽  
Vol 21 ◽  
pp. 101615 ◽  
Author(s):  
Maud van Dorst ◽  
Kees Okkersen ◽  
Roy P.C. Kessels ◽  
Frederick J.A. Meijer ◽  
Darren G. Monckton ◽  
...  

2018 ◽  
Vol 223 (8) ◽  
pp. 3681-3688 ◽  
Author(s):  
Thomas Decramer ◽  
Stijn Swinnen ◽  
Johannes van Loon ◽  
Peter Janssen ◽  
Tom Theys

2014 ◽  
Vol 75 (3) ◽  
pp. 248-256 ◽  
Author(s):  
Bart D. Peters ◽  
Toshikazu Ikuta ◽  
Pamela DeRosse ◽  
Majnu John ◽  
Katherine E. Burdick ◽  
...  

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