An Automatic Ocular Disease Detection Scheme from Enhanced Fundus Images Based on Ensembling Deep CNN Networks

Author(s):  
Ishtiaque Ahmed Khan ◽  
Asaduzzaman Sajeeb ◽  
Shaikh Anowarul Fattah
2019 ◽  
Vol 12 (3) ◽  
pp. 1577-1586 ◽  
Author(s):  
Karthikeyan S. ◽  
Sanjay Kumar P. ◽  
R J Madhusudan Madhusudan ◽  
S K Sundaramoorthy Sundaramoorthy ◽  
P K Krishnan Namboori3

The health-related complications such as diabetes, macular degeneration, inflammatory conditions, ageing and fungal infections may cause damages to the retina and the macula of the eye, leading to permanent vision loss. The major diseases associated with retina are Arteriosclerotic retinopathy (AR), Central retinal vein occlusion (CRVO), Branch retinal artery occlusion (BRAO), Coat's disease (CD) and Hemi-Central Retinal Vein Occlusion (HRVO). The symptomatic variations among these disorders are relatively confusing so that a systematic diagnostic strategy is difficult to set in. Therefore, an early detection device is required that is capable of differentiating the various ophthalmic complications and thereby helping in providing the right treatment to the patient at the right time. In this research work, 'Deep Convolution Neural Networks (Deep CNN) based machine learning approach has been used for the detection of the twelve major retinal complications from the minimal set of fundus images. The model was further cross-validated with real-time fundus images. The model is found to be superior in its efficiency, specificity and ability to minimize the misclassification. The “multi-class retinal disease” model on further cross-validation with real-time fundus image of the gave an accuracy of 95.63 %, validation accuracy of 92.99 % and F1 score of 91.96 %. The multi-class model is found to be a theranostic clinical support system for the ophthalmologist for diagnosing different kinds of retinal problems, especially BRAO, BRVO, CRAO, CD, DR, HRVO, HP, HR, and CN.


Author(s):  
Alan Lima ◽  
Lucas B. Maia ◽  
Pedro Thiago Cutrim Dos Santos ◽  
Geraldo Braz Júnior ◽  
João D. S. De Almeida ◽  
...  

Glaucoma is an ocular disease that causes damage to the eye's optic nerve and successive narrowing of the visual field in affected patients which can lead the patient, in advanced stage, to blindness. This work presents a study on the use of Convolutional Neural Networks (CNNs) for the automatic diagnosis through eye fundus images. However, building a perfect CNN involves a lot of effort that in many situations is not always able to achieve satisfactory results. The objective of this work is to use a Genetic Algorithm (GA) to optimize CNNs architectures through evolution that can helps in glaucoma diagnosis using eye's fundus image from RIM-ONE-r2 dataset. Our partial results demonstrate satisfactory results after training the best individual chosen by GA with the achievement of an accuracy of 91%.


Author(s):  
Yanwu Xu ◽  
Lixin Duan ◽  
Huazhu Fu ◽  
Zhuo Zhang ◽  
Wei Zhao ◽  
...  

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Bansode Balbhim Narhari ◽  
Bakwad Kamlakar Murlidhar ◽  
Ajij Dildar Sayyad ◽  
Ganesh Shahubha Sable

AbstractObjectivesThe focus of this paper is to introduce an automated early Diabetic Retinopathy (DR) detection scheme from colour fundus images through enhanced segmentation and classification strategies by analyzing blood vessels.MethodsThe occurrence of DR is increasing from the past years, impacting the eyes due to a sudden rise in the glucose level of blood. All over the world, half of the people who are under age 70 are severely suffered from diabetes. The patients who are affected by DR will lose their vision during the absence of early recognition of DR and appropriate treatment. To decrease the growth and occurrence of loss of vision, the early detection and timely treatment of DR are desirable. At present, deep learning models have presented better performance using retinal images for DR detection. In this work, the input retinal fundus images are initially subjected to pre-processing that undergoes contrast enhancement by Contrast Limited Adaptive Histogram Equalization (CLAHE) and average filtering. Further, the optimized binary thresholding-based segmentation is done for blood vessel segmentation. For the segmented image, Tri-level Discrete Level Decomposition (Tri-DWT) is performed to decompose it. In the feature extraction phase, Local Binary Pattern (LBP), and Gray-Level Co-occurrence Matrices (GLCMs) are extracted. Next, the classification of images is done through the combination of two algorithms, one is Neural Network (NN), and the other Convolutional Neural Network (CNN). The extracted features are subjected to NN, and the tri-DWT-based segmented image is subjected to CNN. Both the segmentation and classification phases are enhanced by the improved meta-heuristic algorithm called Fitness Rate-based Crow Search Algorithm (FR-CSA), in which few parameters are optimized for attaining maximum detection accuracy.ResultsThe proposed DR detection model was implemented in MATLAB 2018a, and the analysis was done using three datasets, HRF, Messidor, and DIARETDB.ConclusionsThe developed FR-CSA algorithm has the best detection accuracy in diagnosing DR.


2014 ◽  
Vol 20 (4) ◽  
pp. 318-323 ◽  
Author(s):  
April Y. Maa ◽  
Centrael Evans ◽  
William R. DeLaune ◽  
Purnima S. Patel ◽  
Mary G. Lynch

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