Magnetic sensing technology for in vivo tracking

Author(s):  
Nasir Mehmood ◽  
Syed Mahfuzul Aziz
2020 ◽  
Vol 16 (2) ◽  
pp. 65-67
Author(s):  
Adrien Desjardins

Adrien has a PhD from Harvard and the Massachusetts Institute of Technology (both MA, USA) in biomedical engineering and biophysics, with a specific focus on cardiovascular devices, fiber optic sensing and optical coherence tomography. After his PhD, he led technical developments in an internal venture at Philips Research (Eindhoven, Netherlands) to develop devices with integrated optical sensors and brought this technology from benchtop prototypes to in vivo human studies. In addition to his responsibilities at Echopoint Medical (London, UK) where he is Chief Technology Officer, Adrien is also is a Professor of Biomedical Engineering at University College London (London, UK), where he leads the interventional devices group with a vision to develop novel methods for performing physiological measurements and imaging with minimally invasive devices. He has over 52 patent applications and granted patents.


Lab on a Chip ◽  
2014 ◽  
Vol 14 (14) ◽  
pp. 2385 ◽  
Author(s):  
D. Issadore ◽  
Y. I. Park ◽  
H. Shao ◽  
C. Min ◽  
K. Lee ◽  
...  

Cosmetics ◽  
2019 ◽  
Vol 6 (3) ◽  
pp. 54
Author(s):  
Xu Zhang ◽  
Christos Bontozoglou ◽  
Perry Xiao

OTTER (opto-thermal transient emission radiometry) is an infrared remote sensing technology that has been extensively used in skin measurements. It is non-contact, non-invasive, and has a unique depth profiling capability. By selecting different detection wavelengths, OTTER can be used for different types of skin measurements, such as skin hydration measurements and skin topically applied substance measurements, etc. By plotting the results at different detection wavelengths, we can have an opto-thermal detection spectrum. Combining with OTTER’s unique depth profiling capability, we can get a depth-resolved opto-thermal detection spectrum. This is a powerful tool that can be used for many skin studies. Here we will present our latest study with details on the apparatus setup, theoretical background, as well as experimental results.


2019 ◽  
Vol 5 (4) ◽  
pp. 240-256
Author(s):  
Kimisha Ghunowa ◽  
Andrew Scott Medeiros ◽  
Richard Bello

A hyperspectral approach to quantify algal biomass was studied across 30 shallow ponds in the Hudson Bay Lowlands near Churchill, MB. Normalized difference algal indices (NDAI) were calculated based on hyperspectral measurements of the reflectance collected on shore with a hand-held spectrometer in parallel to estimations of biomass with an in vivo fluorometer designed for benthic algae. Algal biomass and coarse assemblages were differentiated through their spectral reflectance as a demonstration of concept for future upscaling that would be necessary for regional monitoring using remote sensing technology. Results indicated strong agreements between the calculated NDAI for measured reflectance from each pond and that of the isolated benthic zone. Cyanobacteria were the dominant component of the algal community for most ponds. As such, measures of reflectance and use of simple NDAIs may be able to characterize the total biomass of northern ponds. However, the distinction between algal groups may require independent validation of algal assemblages for estimations beyond total biomass. Nonetheless, hyperspectral analysis could provide a strong potential for monitoring northern freshwater systems at a regional scale.


2020 ◽  
Vol 1094 ◽  
pp. 151-159
Author(s):  
Qi-Yue Guo ◽  
Shu-Yue Ren ◽  
Jing-Yi Wang ◽  
Ye Li ◽  
Zi-Yi Yao ◽  
...  

Author(s):  
S. Phyllis Steamer ◽  
Rosemarie L. Devine

The importance of radiation damage to the skin and its vasculature was recognized by the early radiologists. In more recent studies, vascular effects were shown to involve the endothelium as well as the surrounding connective tissue. Microvascular changes in the mouse pinna were studied in vivo and recorded photographically over a period of 12-18 months. Radiation treatment at 110 days of age was total body exposure to either 240 rad fission neutrons or 855 rad 60Co gamma rays. After in vivo observations in control and irradiated mice, animals were sacrificed for examination of changes in vascular fine structure. Vessels were selected from regions of specific interest that had been identified on photomicrographs. Prominent ultrastructural changes can be attributed to aging as well as to radiation treatment. Of principal concern were determinations of ultrastructural changes associated with venous dilatations, segmental arterial stenosis and tortuosities of both veins and arteries, effects that had been identified on the basis of light microscopic observations. Tortuosities and irregularly dilated vein segments were related to both aging and radiation changes but arterial stenosis was observed only in irradiated animals.


Author(s):  
E. J. Kollar

The differentiation and maintenance of many specialized epithelial structures are dependent on the underlying connective tissue stroma and on an intact basal lamina. These requirements are especially stringent in the development and maintenance of the skin and oral mucosa. The keratinization patterns of thin or thick cornified layers as well as the appearance of specialized functional derivatives such as hair and teeth can be correlated with the specific source of stroma which supports these differentiated expressions.


Author(s):  
M.J. Murphy ◽  
R.R. Price ◽  
J.C. Sloman

The in vitro human tumor cloning assay originally described by Salmon and Hamburger has been applied recently to the investigation of differential anti-tumor drug sensitivities over a broad range of human neoplasms. A major problem in the acceptance of this technique has been the question of the relationship between the cultured cells and the original patient tumor, i.e., whether the colonies that develop derive from the neoplasm or from some other cell type within the initial cell population. A study of the ultrastructural morphology of the cultured cells vs. patient tumor has therefore been undertaken to resolve this question. Direct correlation was assured by division of a common tumor mass at surgical resection, one biopsy being fixed for TEM studies, the second being rapidly transported to the laboratory for culture.


Author(s):  
H. Engelhardt ◽  
R. Guckenberger ◽  
W. Baumeister

Bacterial photosynthetic membranes contain, apart from lipids and electron transport components, reaction centre (RC) and light harvesting (LH) polypeptides as the main components. The RC-LH complexes in Rhodopseudomonas viridis membranes are known since quite seme time to form a hexagonal lattice structure in vivo; hence this membrane attracted the particular attention of electron microscopists. Contrary to previous claims in the literature we found, however, that 2-D periodically organized photosynthetic membranes are not a unique feature of Rhodopseudomonas viridis. At least five bacterial species, all bacteriophyll b - containing, possess membranes with the RC-LH complexes regularly arrayed. All these membranes appear to have a similar lattice structure and fine-morphology. The lattice spacings of the Ectothiorhodospira haloohloris, Ectothiorhodospira abdelmalekii and Rhodopseudomonas viridis membranes are close to 13 nm, those of Thiocapsa pfennigii and Rhodopseudomonas sulfoviridis are slightly smaller (∼12.5 nm).


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