Detection of abnormal process behavior in copper solvent extraction by Hotelling T2and squared prediction error control chart

2016 ◽  
Author(s):  
Kirill Filianin ◽  
Satu-Pia Reinikainen ◽  
Tuomo Sainio ◽  
Heli Helaakoski ◽  
Vesa Kyllonen
Keyword(s):  
Solvent Extraction ◽  
Control Chart ◽  
Prediction Error ◽  
Error Control ◽  
Squared Prediction Error ◽  
Process Behavior ◽  
Copper Solvent Extraction

Effects of Copper Extraction-Stripping Loops on Entrainment in Aqueous Raffinate

2014 ◽  
Vol 908 ◽  
pp. 18-21
Author(s):  
Yan Jun Liu ◽  
Xiao Rong Liu ◽  
Hui Li ◽  
Yong Sheng Li ◽  
Qing Li ◽  
...  
Keyword(s):  
Surface Tension ◽  
Solvent Extraction ◽  
Early Stage ◽  
Organic Chemical ◽  
Copper Extraction ◽  
Organic Chemicals ◽  
Stabilization Mechanism ◽  
Absolute Value ◽  
Copper Solvent Extraction ◽  
Average Size

Effects of extraction-stripping loops of organic phase on organic chemical entrainment in the aqueous raffinate in copper solvent extraction were studied in this paper. Results demonstrated that the total amount of organic chemicals lost in the aqueous raffinate decreased with the increase of times of extraction-stripping loops but reached largest at third loop. Entrainment was the dominate way of organic chemicals losing in the aqueous raffinate at early stage of the loops. The formation of entrainment and its stabilization mechanism was also studied. The average size of entrained droplet trended to increase with extraction-stripping loops increasing. Meanwhile, the absolute value of zeta potential trended to decrease. The surface tension of the aqueous raffinate increased after reaching the minimum value 41.3 mN/m at the 3rd loop. It showed that the formation of entrained droplets and its stability were mainly affected by the surface tension of aqueous raffinate.

scholarly journals A Monitoring System for the Copper Solvent Extraction - Electrowinning Process

2003 ◽  
Vol 36 (24) ◽  
pp. 257-262
Author(s):  
Ville Suontaka ◽  
Kari Saloheimo ◽  
Tom Marttila ◽  
Sirkka-Liisa Jämsä-Jounela
Keyword(s):  
Solvent Extraction ◽  
Monitoring System ◽  
Copper Solvent Extraction

Diversity of Bioleaching Microorganisms in Interfacial Emulsion of Copper Solvent Extraction

2015 ◽  
Vol 1130 ◽  
pp. 55-58
Author(s):  
Xiao Rong Liu ◽  
Chang Su ◽  
Dao Jie Chi ◽  
Xue Song Zheng ◽  
Hua Long Yu ◽  
...  
Keyword(s):  
Solvent Extraction ◽  
16S Rrna ◽  
Acidithiobacillus Ferrooxidans ◽  
Gene Sequencing ◽  
16S Rrna Gene Sequencing ◽  
Extraction Process ◽  
Copper Extraction ◽  
Rrna Gene ◽  
Copper Solvent Extraction ◽  
Rrna Gene Sequencing

In the bioleaching - solvent extraction - electrowinning practices for copper extraction, the solvent extraction process is used to enrich the copper in the leachate to a high lever to make the sequent electrowinning process possible. O/W type of interfacial emulsion always forms at the interface between organic phase and aqueous phase in the solvent extraction practices. Diversified microorganisms were discovered by microscope growing in the interface emulsion of copper solvent extraction. The diversity of them was analyzed by using 16s rRNA gene sequencing. It was indicated that there exist seven categories of bacteria in the interface emulsion, among which common bioleaching bacteria, such as Leptospirillum sp.,Acidithiobacillus ferrooxidans, Metallibacterium sp., are included. The dominant strains are Leptospirillum sp. E4-L9 and Acidithiobacillus ferrooxidans ATCC 23270, which account up to 40.48 % and 38.1 %, respectively. It was uncovered that bioleaching bacteria can be intercepted by interfacial emulsion of solvent extraction to make their population in the raffinate lower and the efficiency of bioleaching decrease consequently.

Accuracy of predicting the vancomycin concentration in Japanese cancer patients by the Sawchuk–Zaske method or Bayesian method

2019 ◽  
Vol 26 (3) ◽  
pp. 543-548
Author(s):  
Toshihisa Nakashima ◽  
Takayuki Ohno ◽  
Keiichi Koido ◽  
Hironobu Hashimoto ◽  
Hiroyuki Terakado
Keyword(s):  
Cancer Patients ◽  
Prediction Error ◽  
Bayesian Method ◽  
Predictive Accuracy ◽  
Pharmacokinetic Parameters ◽  
Population Pharmacokinetic ◽  
Squared Prediction Error ◽  
Trough Concentrations ◽  
The Mean ◽  
Mean Prediction Error

Background In cancer patients treated with vancomycin, therapeutic drug monitoring is currently performed by the Bayesian method that involves estimating individual pharmacokinetics from population pharmacokinetic parameters and trough concentrations rather than the Sawchuk–Zaske method using peak and trough concentrations. Although the presence of malignancy influences the pharmacokinetic parameters of vancomycin, it is unclear whether cancer patients were included in the Japanese patient populations employed to estimate population pharmacokinetic parameters for this drug. The difference of predictive accuracy between the Sawchuk–Zaske and Bayesian methods in Japanese cancer patients is not completely understood. Objective To retrospectively compare the accuracy of predicting vancomycin concentrations between the Sawchuk–Zaske method and the Bayesian method in Japanese cancer patients. Methods Using data from 48 patients with various malignancies, the predictive accuracy (bias) and precision of the two methods were assessed by calculating the mean prediction error, the mean absolute prediction error, and the root mean squared prediction error. Results Prediction of the trough and peak vancomycin concentrations by the Sawchuk–Zaske method and the peak concentration by the Bayesian method showed a bias toward low values according to the mean prediction error. However, there were no significant differences between the two methods with regard to the changes of the mean prediction error, mean absolute prediction error, and root mean squared prediction error. Conclusion The Sawchuk–Zaske method and Bayesian method showed similar accuracy for predicting vancomycin concentrations in Japanese cancer patients.

Attachment of Acidithiobacillus ferrooxidans and Bioleaching of Chalcopyrite under Influence of Organic Substances Associated with Copper Solvent Extraction

2017 ◽  
Vol 262 ◽  
pp. 75-78 ◽  
Author(s):  
Xiao Rong Liu ◽  
Hao Zhang ◽  
Hua Long Yu ◽  
Yan Hao Zhu
Keyword(s):  
Solvent Extraction ◽  
Acidithiobacillus Ferrooxidans ◽  
Low Grade ◽  
Organic Substances ◽  
Copper Solvent Extraction ◽  
Influence Of Solvent

Small quantities of organic substances are inevitably entrained and dissolve in the aqueous raffinate during a copper solvent extraction (SX) operation. These organic substances contaminate the bioleaching environment through the loopback of the raffinate. The attachment of cells of Acidithiobacillus ferrooxidans (At. ferrooxidans) to the low grade chalcopyrite ores and the bioleaching of the ores under the influence of solvent extraction organic substances were investigated. The results showed that the cells of At. ferrooxidans were apt to attach on the SX organics-contaminated chalcopyrite ores with an adsorption ratio of about 83%, larger than that of 44% on the uncontaminated ores as a control. However, the bioleaching efficiency decreased from 25% to 15% under the influence of the SX organic substances. Obviously, an improvement of the cells attachment did not improve the bioleaching efficiency of the low grade chalcopyrite ores by At. ferrooxidans in the present of the SX organic substances. The SX organic substances impacted the metabolism of At.ferrooxidans and their bioleaching ability.

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