ACAPELLA-5K, a high-throughput automated genome and chemical analysis system

Author(s):  
D.R. Meldrum ◽  
C.H. Fisher ◽  
M.P. Moore ◽  
M. Saini ◽  
M.R. Holl ◽  
...  
Author(s):  
Lipeng He ◽  
Xiaoqiang Wu ◽  
Zheng Zhang ◽  
Zhe Wang ◽  
Bangcheng Zhang ◽  
...  

Piezoelectric pumps are applied in many fields, such as chemical analysis system and fluid pumping systems. Piezoelectric pumps with high output pressure can meet the needs of more fields. This article introduces the design and fabrication of a high output pressure piezoelectric pump with straight arm wheeled check valve. In this paper, the influence of straight arm wheeled check valve on the output pressure of piezoelectric pump is deeply discussed from the aspect of energy loss. This study investigated the effect of valve arm number ( N = 2, 3,4, and 5), the valve arm width ( W = 0.8, 1.0, and 1.2 mm), and the valve arm length ( L = 1.92, 2.02, and 2.12 mm) on the output pressure of piezoelectric pump. The output pressure characteristic of straight arm wheeled check valve piezoelectric pump with different valve parameters is obtained by experiment. Experimental results show that when N = 4, W = 1.0 mm, L = 2.02 mm, the output pressure of the straight arm wheeled check valve piezoelectric pump has the best output pressure of 27.41 kPa at 220 V and 85 Hz. This study provides a reference for the further application of piezoelectric pumps in fluid pumping field.


1993 ◽  
Vol 13 (1-3) ◽  
pp. 333-335 ◽  
Author(s):  
Bart H. van der Schoot ◽  
Sylvain Jeanneret ◽  
Albert van den Berg ◽  
Nico F. de Rooij

1993 ◽  
Vol 15 (1-3) ◽  
pp. 211-213 ◽  
Author(s):  
Bart H. van der Schoot ◽  
Sylvain Jeanneret ◽  
Albert van den Berg ◽  
Nico F. de Rooij

2016 ◽  
Author(s):  
H. M. Kingston ◽  
M. L. Kingston

Science ◽  
1993 ◽  
Vol 261 (5123) ◽  
pp. 895-897 ◽  
Author(s):  
D. J. Harrison ◽  
K. Fluri ◽  
K. Seiler ◽  
Z. Fan ◽  
C. S. Effenhauser ◽  
...  

2005 ◽  
Vol 10 (4) ◽  
pp. 374-382 ◽  
Author(s):  
Susan M. Young ◽  
Cristian Bologa ◽  
Eric R. Prossnitz ◽  
Tudor I. Oprea ◽  
Larry A. Sklar ◽  
...  

High-throughput flow cytometry (HTFC), enabled by faster automated sample processing, represents a promising high- content approach for compound library screening. HyperCyt® is a recently developed automated HTFC analysis system by which cell samples are rapidly aspirated from microplate wells and delivered to the flow cytometer. The formylpeptide receptor (FPR) family of G protein–coupled receptors contributes to the localization and activation of tissue-damaging leukocytes at sites of chronic inflammation. Here, the authors describe development and application of an HTFC screening approach to detect potential anti-inflammatory compounds that block ligand binding to FPR. Using a homogeneous no-wash assay, samples were routinely processed at 1.5 s/well (~2500 cells analyzed/sample), allowing a 96-well plate to be processed in less than 2.5 min. Assay sensitivity and accuracy were validated by detection of a previously documented active compound with relatively low FPR affinity (sulfinpyrazone, inhibition constant [Ki]=14 μM) from among a collection of 880 compounds in the Prestwick Chemical Library. The HyperCyt® system was therefore demonstrated to be a robust, sensitive, and highly quantitative method with which to screen lead compound libraries in a 96-well format.


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