The application of cloud computing technology provides a new idea to the development of mobile learning. The applications based on cloud computing is focus on the solution of music appreciation class in the paper. The design of mobile learning system for music appreciation class based on cloud computing is proposed and the related concepts of cloud computing is briefly introduced. The topology of the system is given. In the end, it shows deeply mobile learning system class based on cloud computing is the urgency of education development. It can provide the better services of music appreciation class.