Case-control study of chronic low-level exposure of inorganic arsenic species and non-melanoma skin cancer

2017 ◽  
Vol 44 (12) ◽  
pp. 1374-1379 ◽  
Author(s):  
Tae-Hoon Kim ◽  
Jeong-Wook Seo ◽  
Young-Seoub Hong ◽  
Ki-Hoon Song
Keyword(s):  
Skin Cancer ◽  
Case Control Study ◽  
Inorganic Arsenic ◽  
Arsenic Species ◽  
Case Control ◽  
Low Level ◽  
Non Melanoma Skin Cancer ◽  
Inorganic Arsenic Species ◽  
Control Study ◽  
Melanoma Skin

scholarly journals Photosensitizing Agents and the Risk of Non-Melanoma Skin Cancer: A Population-Based Case–Control Study

2013 ◽  
Vol 133 (8) ◽  
pp. 1950-1955 ◽  
Author(s):  
Sarah N. Robinson ◽  
Michael S. Zens ◽  
Ann E. Perry ◽  
Steven K. Spencer ◽  
Eric J. Duell ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Non Melanoma Skin Cancer ◽  
Photosensitizing Agents ◽  
Control Study ◽  
Melanoma Skin

scholarly journals Physician-based Case Control Study of Non-melanoma Skin Cancer in Baytown, Texas

1996 ◽  
Vol 46 (3) ◽  
pp. 186-196 ◽  
Author(s):  
J. F. Gamble ◽  
S. E. Lerman ◽  
W. R. Holder ◽  
M. J. Nicolich ◽  
C. M. Yarborough
Keyword(s):  
Skin Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Non Melanoma Skin Cancer ◽  
Control Study ◽  
Melanoma Skin

Case–control study of smoking and non-melanoma skin cancer

2011 ◽  
Vol 23 (2) ◽  
pp. 245-254 ◽  
Author(s):  
Dana E. Rollison ◽  
Michelle R. Iannacone ◽  
Jane L. Messina ◽  
L. Frank Glass ◽  
Anna R. Giuliano ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Non Melanoma Skin Cancer ◽  
Control Study ◽  
Melanoma Skin

scholarly journals Vitamin D Receptor Polymorphisms and Non-Melanoma Skin Cancer Risk: A Case-Control Study

2020 ◽  
Vol 9 (12) ◽  
pp. 3819
Author(s):  
Carolina Morgado-Águila ◽  
Purificación Rey-Sánchez ◽  
Guadalupe Gil-Fernández ◽  
María Carmen Costa-Fernández ◽  
Francisco José Rodríguez-Velasco
Keyword(s):  
Vitamin D ◽  
Skin Cancer ◽  
Basal Cell ◽  
Protective Factor ◽  
Case Control Study ◽  
Case Control ◽  
Non Melanoma Skin Cancer ◽  
Skin Cancers ◽  
Control Study ◽  
Melanoma Skin

Exposure to sunlight is the major source of vitamin D and the main environmental cause of non-melanocytic skin cancers. Vitamin D, partly mediated through the vitamin D receptor (VDR), has potential therapeutic applications in skin cancer. The aim of this study was to investigate the association of BsmI and ApaI VDR polymorphisms among patients with non-melanoma cancers and controls. An observational case-control study was conducted in a sample of 154 subjects. We observed no significant effects between these polymorphisms and skin cancer risk. When stratified for gender, GG and AG BsmI polymorphisms significantly increased the risk of basal cell carcinomas in males. In relation to ApaI, all three polymorphisms significantly increased the risk of basal cell carcinoma in males. When stratified for age, we found that being 70 years of age or younger was a protective factor against both skin cancers. Being a female and 70 years old or younger was a protective factor for basal cell carcinoma. A comparison of the frequencies of the VDR genotypes in patients older than 70 years vs. 70 years or younger also revealed age-dependent variations in patients with non-melanoma skin cancer. Our study suggests a role for VDR polymorphisms in non-melanoma skin cancer development.

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