Comparative Cytokine Release from Human Monocytes, Monocyte-Derived Immature Mast Cells, and a Human Mast Cell Line (HMC-1)

1994 ◽  
Vol 103 (4) ◽  
pp. 504-508 ◽  
Author(s):  
Jürgen Grabbe ◽  
P.i.a. Welker ◽  
Annelie Möller ◽  
Edgar Dippel ◽  
Leonie K Ashman ◽  
...  
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Cell Line ◽  
Human Mast Cell ◽  
Human Monocytes ◽  
Cytokine Release ◽  
Mast Cell Line

Cytokine release from a human mast cell line (HMC-1) in response to stimulation with anti-IgE and other secretagogues

2000 ◽  
Vol 49 (S1) ◽  
pp. 7-8 ◽  
Author(s):  
J. Wierecky ◽  
J. Grabbe ◽  
H. H. Wolff ◽  
B. F. Gibbs
Keyword(s):  
Mast Cell ◽  
Cell Line ◽  
Human Mast Cell ◽  
Cytokine Release ◽  
Mast Cell Line

Dexamethasone suppresses gene expression and production of IL-13 by human mast cell line and lung mast cells

1998 ◽  
Vol 102 (1) ◽  
pp. 134-142 ◽  
Author(s):  
Toshiaki Fushimi ◽  
Hiroshi Okayama ◽  
Sanae Shimura ◽  
Hiroki Saitoh ◽  
Kunio Shirato
Keyword(s):  
Gene Expression ◽  
Mast Cell ◽  
Mast Cells ◽  
Cell Line ◽  
Human Mast Cell ◽  
Mast Cell Line

Effects of the Chinese herbal formula Shi-Bi-Lin on cytokine release from the human mast cell line

2005 ◽  
Vol 95 (1) ◽  
pp. 79-85 ◽  
Author(s):  
Yu Zhao ◽  
Charles A. van Hasselt ◽  
John K.S. Woo ◽  
George G. Chen ◽  
Yeuk O. Wong ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Line ◽  
Human Mast Cell ◽  
Herbal Formula ◽  
Cytokine Release ◽  
Chinese Herbal Formula ◽  
Chinese Herbal ◽  
Mast Cell Line

Effects of the Schisandra Fructus Water Extract on Cytokine Release from a Human Mast Cell Line

2006 ◽  
Vol 9 (4) ◽  
pp. 480-486 ◽  
Author(s):  
Ok Hwa Kang ◽  
Hee-Sung Chae ◽  
Jung-Hyun Choi ◽  
Hyuk Joon Choi ◽  
Pil Sang Park ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Line ◽  
Water Extract ◽  
Human Mast Cell ◽  
Cytokine Release ◽  
Mast Cell Line

Inhibitory effects of budesonide, desloratadine and dexamethasone on cytokine release from human mast cell line (HMC-1)

2004 ◽  
Vol 53 (12) ◽  
pp. 664-669 ◽  
Author(s):  
Y. Zhao ◽  
P. C. Leung ◽  
K. S. Woo ◽  
G. G. Chen ◽  
Y. O. Wong ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Line ◽  
Human Mast Cell ◽  
Cytokine Release ◽  
Inhibitory Effects ◽  
Mast Cell Line

In vitro inhibitory effect of rupatadine on histamine and TNF-α release from dispersed canine skin mast cells and the human mast cell line HMC-1

2000 ◽  
Vol 49 (7) ◽  
pp. 355-360 ◽  
Author(s):  
M. Queralt ◽  
P. Brazís ◽  
M. Merlos ◽  
F. de Mora ◽  
A. Puigdemont
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Cell Line ◽  
Inhibitory Effect ◽  
Human Mast Cell ◽  
Tnf Α ◽  
Mast Cell Line

scholarly journals Disrupted Lipid Raft Shuttling of FcεRI by n-3 Polyunsaturated Fatty Acid Is Associated With Ligation of G Protein-Coupled Receptor 120 (GPR120) in Human Mast Cell Line LAD2

2020 ◽  
Vol 7 ◽  
Author(s):  
Xiaofeng Wang ◽  
Ramses Ilarraza ◽  
Brian P. Tancowny ◽  
Syed Benazir Alam ◽  
Marianna Kulka
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Cell Line ◽  
G Protein ◽  
Lipid Raft ◽  
Human Mast Cell ◽  
G Protein Coupled Receptor ◽  
Cell Functions ◽  
Mast Cell Line ◽  
G Protein Coupled

n-3 polyunsaturated fatty acids (PUFA) influences a variety of disease conditions, such as hypertension, heart disease, diabetes, cancer and allergic diseases, by modulating membrane constitution, inhibiting production of proinflammatory eicosanoids and cytokines, and binding to cell surface and nuclear receptors. We have previously shown that n-3 PUFA inhibit mast cell functions by disrupting high affinity IgE receptor (FcεRI) lipid raft partitioning and subsequent suppression of FcεRI signaling in mouse bone marrow-derived mast cells. However, it is still largely unknown how n-3 PUFA modulate human mast cell function, which could be attributed to multiple mechanisms. Using a human mast cell line (LAD2), we have shown similar modulating effects of n-3 PUFA on FcεRI lipid raft shuttling, FcεRI signaling, and mediator release after cell activation through FcεRI. We have further shown that these effects are at least partially associated with ligation of G protein-coupled receptor 120 expressed on LAD2 cells. This observation has advanced our mechanistic knowledge of n-3 PUFA's effect on mast cells and demonstrated the interplay between n-3 PUFA, lipid rafts, FcεRI, and G protein-coupled receptor 120. Future research in this direction may present new targets for nutritional intervention and therapeutic agents.

Effects of the Chinese Herbal Formula CUF2 on Cytokine Release from Human Mast Cell Line

2007 ◽  
Vol 119 (1) ◽  
pp. S213 ◽  
Author(s):  
Y.O. Wong ◽  
R.Y.T. Sung ◽  
K. Li ◽  
Y. Zhao ◽  
A.M.C. Li ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Line ◽  
Human Mast Cell ◽  
Herbal Formula ◽  
Cytokine Release ◽  
Chinese Herbal Formula ◽  
Chinese Herbal ◽  
Mast Cell Line
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