scholarly journals Repeated restraint stress exposure during early withdrawal accelerates incubation of cue-induced cocaine craving

2016 ◽  
Vol 23 (1) ◽  
pp. 80-89 ◽  
Author(s):  
Ryan M. Glynn ◽  
J. Amiel Rosenkranz ◽  
Marina E. Wolf ◽  
Aaron Caccamise ◽  
Freya Shroff ◽  
...  
Keyword(s):  
Restraint Stress ◽  
Stress Exposure ◽  
Early Withdrawal ◽  
Repeated Restraint Stress ◽  
Cocaine Craving

scholarly journals Chronic repeated restraint stress increases prolactin-releasing peptide/tyrosine-hydroxylase ratio with gender-related differences in the rat brain

2007 ◽  
Vol 0 (0) ◽  
pp. 071115085713008-??? ◽  
Author(s):  
Zsuzsanna E. Tóth ◽  
Dóra Zelena ◽  
Zsuzsa Mergl ◽  
Eszter Kirilly ◽  
Péter Várnai ◽  
...  
Keyword(s):  
Tyrosine Hydroxylase ◽  
Rat Brain ◽  
Restraint Stress ◽  
Repeated Restraint Stress ◽  
Prolactin Releasing Peptide

Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy.

1999 ◽  
Vol 113 (5) ◽  
pp. 902-913 ◽  
Author(s):  
Cheryl D. Conrad ◽  
Ana María Magariños ◽  
Joseph E. LeDoux ◽  
Bruce S. McEwen
Keyword(s):  
Fear Conditioning ◽  
Restraint Stress ◽  
Repeated Restraint Stress ◽  
Hippocampal Ca3 ◽  
Dendritic Atrophy

scholarly journals C60 Fullerene Prevents Restraint Stress-Induced Oxidative Disorders in Rat Tissues: Possible Involvement of the Nrf2/ARE-Antioxidant Pathway

2018 ◽  
Vol 2018 ◽  
pp. 1-17 ◽  
Author(s):  
Olga O. Gonchar ◽  
Andriy V. Maznychenko ◽  
Nataliya V. Bulgakova ◽  
Inna V. Vereshchaka ◽  
Tomasz Tomiak ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Protein Expression ◽  
Restraint Stress ◽  
Stress Condition ◽  
Rat Tissues ◽  
Stress Exposure ◽  
The Brain ◽  
Nrf2 Protein

The effects of C60FAS (50 and 500 μg/kg) supplementation, in a normal physiological state and after restraint stress exposure, on prooxidant/antioxidant balance in rat tissues were explored and compared with the effects of the known exogenous antioxidant N-acetylcysteine. Oxidative stress biomarkers (ROS, O2⋅−, H2O2, and lipid peroxidation) and indices of antioxidant status (MnSOD, catalase, GPx, GST, γ-GCL, GR activities, and GSH level) were measured in the brain and the heart. In addition, protein expression of Nrf2 in the nuclear and cytosol fractions as well as the protein level of antiradical enzyme MnSOD and GSH-related enzymes γ-GCLC, GPx, and GSTP as downstream targets of Nrf2 was evaluated by western blot analysis. Under a stress condition, C60FAS attenuates ROS generation and O2⋅− and H2O2 releases and thus decreases lipid peroxidation as well as increases rat tissue antioxidant capacity. We have shown that C60FAS supplementation has dose-dependent and tissue-specific effects. C60FAS strengthened the antiradical defense through the upregulation of MnSOD in brain cells and maintained MnSOD protein content at the control level in the myocardium. Moreover, C60FAS enhanced the GSH level and the activity/protein expression of GSH-related enzymes. Correlation of these changes with Nrf2 protein content suggests that under stress exposure, along with other mechanisms, the Nrf2/ARE-antioxidant pathway may be involved in regulation of glutathione homeostasis. In our study, in an in vivo model, when C60FAS (50 and 500 μg/kg) was applied alone, no significant changes in Nrf2 protein expression as well as in activity/protein levels of MnSOD and GSH-related enzymes in both tissues types were observed. All these facts allow us to assume that in the in vivo model, C60FAS affects on the brain and heart endogenous antioxidative statuses only during the oxidative stress condition.

scholarly journals Effect of repeated restraint stress on memory in different tasks

1999 ◽  
Vol 32 (3) ◽  
pp. 341-347 ◽  
Author(s):  
G.D. Gamaro ◽  
M.B. Michalowski ◽  
D.H. Catelli ◽  
M.H. Xavier ◽  
C. Dalmaz
Keyword(s):  
Restraint Stress ◽  
Repeated Restraint Stress

Repeated Restraint Stress Decreases Na,K-ATPase Activity via Oxidative and Nitrosative Damage in the Frontal Cortex of Rats

Neuroscience ◽  
2018 ◽  
Vol 393 ◽  
pp. 273-283 ◽  
Author(s):  
Leonardo Santana Novaes ◽  
Nilton Barreto dos Santos ◽  
Guilherme Dragunas ◽  
Juliano Genaro Perfetto ◽  
Juan Carlos Leza ◽  
...  
Keyword(s):  
Atpase Activity ◽  
Frontal Cortex ◽  
Restraint Stress ◽  
Repeated Restraint Stress
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