A comparative study of the effects of gutta‐percha solvents on human osteoblasts and murine fibroblasts

Author(s):  
Gul Ipek Gundogan ◽  
Sare Durmus ◽  
Gulgun Cansu Ozturk ◽  
Nazmi Kucukyesil ◽  
Yasin Talat Acar ◽  
...  

2008 ◽  
Vol 22 (4) ◽  
pp. 337-352 ◽  
Author(s):  
Damiano Pasqualini ◽  
Nicola Scotti ◽  
Livio Mollo ◽  
Elio Berutti ◽  
Emma Angelini ◽  
...  


2021 ◽  
Vol 10 (11) ◽  
pp. e34101119354
Author(s):  
Liliane de Sousa Silva ◽  
Christiane França Martins ◽  
Fernando Yano Abrão ◽  
Camila Aline Romano ◽  
Soraia Ferreira Bezerra ◽  
...  

Eugenia punicifolia (Kunth) D.C., Myrtaceae, known as “pedra-ume-caá”, is popularly used in the treatment of inflammation, infections, fever, flu, diabetes, and diarrhea. This study aimed to carry out a comparative study of the chemical composition of volatile oil from E. punicifolia leaves collected in Goiás and Minas Gerais, as well as to evaluate the larvicidal activity against Aedes aegypti L3 larvae, the antimicrobial activity against bacteria, pathogenic fungi, and environmental, and cytotoxic activity to Balb 3T3 cells (murine fibroblasts). Volatile oils were obtained by hydrodistillation in a Clevenger apparatus and analyzed by Gas Chromatography Coupled to Mass Spectrometry (CG/MS). A total of 60 compounds were identified, the main components found in the leaves of Goiás being Germacrene D, bicyclogermacrene and β-longipenene and in the leaves collected in Minas Gerais they were (Z)-caryophyllene, γ-cadinene, spathulenol, caryophyllene oxide, and α-cadinol. The larvicidal effect was moderate against Ae. aegypti, with LC50 of 85.53 µg / mL for samples from Goiás and LC50 of 91.52 µg / mL for samples from Minas Gerais. Both oils showed moderate bactericidal activity against K. rhiziphyla (ATCC 9341), M. luteus (ATCC 10240), and S. aureus (ATCC 29737). The oils from Goiás (IC50 706.7 µg / mL) and Minas Gerais (IC50 160.7 µg / mL) had a lower cytotoxic concentration than the toxic action for larvae and bacteria, evidencing a safety profile and an interesting therapeutic potential, mainly concerning to volatile oil from Goiás. Therefore, the volatile oils from E. punicifolia leaves collected in Goiás and Minas Gerais that presented moderate larvicidal activity for Ae. aegypti also presented a bactericide activity and less cytotoxicity against murine fibroblasts. This is the first study of the larvicidal, antimicrobial and cytotoxic activity of volatile oils from E. punicifolia leaves.



2016 ◽  
Vol 695 ◽  
pp. 12-19
Author(s):  
Mihaela Jana Ţuculină ◽  
Lelia Gheorghiţă ◽  
Oana Andreea Diaconu ◽  
Marilena Bătăiosu ◽  
Ionela Teodora Dascălu ◽  
...  

AIM: This study draws a comparison, through the transparentization method, focusing on the quality of the canal obturation made with thermoplasticized gutta-percha, between two different systems: GuttaMaster VDW (München, Germany), based on obturators made of a plastic core, covered in alpha gutta-percha, and a system of vertical warm condensation.MATERIALS AND METHODS: The study focused on twenty teeth extracted for various reasons which underwent the endodontic treatment realized through a hybrid technique, using the rotary files system of NiTi MTWO (VDW, München, Germany), and the manual files k-file type (Kendo, VDW, München, Germany). The teeth were distributed into two groups of ten. The teeth in the first group underwent obturation using the CWC technique of vertical warm obturation, and the teeth in the second group underwent root obturation using the GuttaMaster system (VDW, München, Germany). The teeth were decalcified in nitric acid. Using the method of transparentization with methyl salicylate, there were emphasized aspects regarding the abilities of each method to seal three-dimensionally the endodontic space.RESULTS: The teeth which underwent vertical obturation presented many more holes in the obturation material, holes situated mainly in the medial and coronary third. However, these teeth presented the highest degree of insertion in the lateral canals, as compared to the other obturation technique employed. The homogeneity of the root obturation had not had any statistical significant differences between the two techniques. However, the technique of injecting thermoplasticized gutta-percha was superior to the other one regarding the tightness on the edge and the degree of penetration in the lateral canals.CONCLUSIONS: The knowledge of both the qualities and the limits of the obturation material chosen, as well as the correctness of performing the two techniques, determines a definite improvement of the quality of the canal treatment, which ends with a three-dimensional canal obturation.



2020 ◽  
pp. 76-78
Author(s):  
S. I. Tokmakova ◽  
Yu. V. Lunitsyna ◽  
O. V. Bondarenko ◽  
I. N. Chechina ◽  
I. S. Besedina


2018 ◽  
Vol 9 (6) ◽  
pp. 261
Author(s):  
Bobbin Gill ◽  
Kaveri Baruah ◽  
Nitin Mirdha ◽  
Nirmala Bishnoi ◽  
Tarun Gupta ◽  
...  


1997 ◽  
Vol 39 (3) ◽  
pp. 133-135 ◽  
Author(s):  
M. Ömer Görduysus ◽  
Fügen Tasman ◽  
Serdar Tuncer ◽  
Ilker Etikan




2002 ◽  
Vol 35 (12) ◽  
pp. 1005-1011 ◽  
Author(s):  
D. Da Silva ◽  
U. Endal ◽  
A. Reynaud ◽  
I. Portenier ◽  
D. Ørstavik ◽  
...  


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