Oxidative stress in benign prostate hyperplasia

Andrologia ◽  
2015 ◽  
Vol 48 (1) ◽  
pp. 69-73 ◽  
Author(s):  
N. Zabaiou ◽  
D. Mabed ◽  
J. M. Lobaccaro ◽  
M. Lahouel
Keyword(s):  
Oxidative Stress ◽  
Benign Prostate Hyperplasia ◽  
Prostate Hyperplasia ◽  
Benign Prostate

scholarly journals Neferine improves oxidative stress and apoptosis in benign prostate hyperplasia via Nrf2-ARE pathway.

Redox Report ◽  
2021 ◽  
Vol 26 (1) ◽  
pp. 1-9
Author(s):  
Nabila Jahan ◽  
Apu Chowdhury ◽  
Ting Li ◽  
Ke Xu ◽  
Fen Wei ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Benign Prostate Hyperplasia ◽  
Prostate Hyperplasia ◽  
Benign Prostate

scholarly journals Association ofGSTM1andGSTT1Polymorphism with Lipid Peroxidation in Benign Prostate Hyperplasia and Prostate Cancer: A Pilot Study

2011 ◽  
Vol 30 (4) ◽  
pp. 163-169 ◽  
Author(s):  
Vivek Kumar ◽  
Chandra Shekhar Yadav ◽  
Sudip Kumar Datta ◽  
Satyender Singh ◽  
Rafat S. Ahmed ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Prostate Cancer ◽  
Benign Prostate Hyperplasia ◽  
Thiobarbituric Acid ◽  
Study Groups ◽  
Thiobarbituric Acid Reactive Substance ◽  
Prostate Hyperplasia ◽  
Double Deletion ◽  
Markers Of Oxidative Stress ◽  
Benign Prostate

Association of glutathione S-transferase (GST)M1andT1deletions with benign prostate hyperplasia (BPH) and prostate cancer is well reported. These enzymes metabolize numerous toxins thus protecting from oxidative injury. Oxidative stress has been associated with development of BPH and prostate cancer. The present study was designed to analyze role ofGSTdeletions in development of oxidative stress in these subjects. GSTs are responsible for metabolism of toxins present in tobacco therefore effect of tobacco usage in study groups was also studied. Three groups of subjects: BPH (57 patients), prostate cancer (53 patients) and controls (46 subjects) were recruited. Genotyping was done using a multiplex polymerase chain reaction (PCR) method. Malondialdehyde (MDA) levels as marker of oxidative stress were estimated by measuring thiobarbituric acid reactive substance (TBARS) in plasma. Based on genotyping, subjects were categorized into:GSTM1+/GSTT1+, GSTM1-/GSTT1+, GSTM1+/GSTT1- and GSTM1-/GSTT1-. Significantly higher plasma MDA levels were noticed inGSTM1-/GSTT1- as compared toGSTM1+/GSTT1+in all study groups. Double deletion (GSTM1-/GSTT1-) is associated with higher oxidative stress which might play a role in the pathogenesis of BPH and prostate cancer. However, other markers of oxidative stress should be analyzed before any firm conclusion.

HUBUNGAN USIA, OBESITAS DAN RIWAYAT PENYAKIT DIABETES MELLITUS DENGAN KEJADIAN BENIGN PROSTATE HYPERPLASIA (BPH) DERAJAT IV DI RSUD DR. M. HAULUSSY AMBON PERIODE 2012-2014

2017 ◽  
pp. 141-151
Author(s):  
Andrew Ruspanah
Keyword(s):  
Diabetes Mellitus ◽  
Benign Prostate Hyperplasia ◽  
Chi Square ◽  
Cross Sectional ◽  
Prostate Hyperplasia ◽  
Benign Prostate

Pendahuluan. Benign Postate Hiperplasia (BPH) adalah penyakit yang umumnya terjadi pada pria lansia yang disebabkan oleh penuaan. Hiperplasia prostat adalah pertumbuhan jaringan nodul fibroadenomatosa pada prostat. Pembesaran prostat jinak merupakan penyakit yang tersering kedua setelah batu saluran kemih didapatkan secara klinis di Indonesia. Tujuan. Penelitian ini bertujuan untuk mengetahui hubungan antara usia, obesitas dan riwayat diabetes mellitus dengan kejadian Benign Prostate Hyperplasia (BPH) grade IV di Rumah Sakit Dr. M. Haulussy Ambon periode 2012-2014. Metode. Jenis penelitian ini adalah penelitian analitik desain Cross-Sectional, dengan menggunakan catatan medis data di ruang operasi di Rumah Sakit Dr. M. Haulussy Ambon Tahun 2012-2014 dan memperoleh jumlah sampel yang memenuhi kriteria inklusi sebanyak 239, yang diambil dengan teknik total sampling. Analisis dilakukan dengan analisis univariat dan bivariat menggunakan uji Chi Square. Hasil yang di temukan dalam penelitian ini bahwa kejadian BPH lebih besar pada mereka yang berusia> 65 tahun dan 56-65 tahun dibandingkan dengan usia 46-55 dan <46 tahun dengan hasil tes menunjukkan adanya hubungan antara usia dengan BPH dengan nilai (p= 0,000), ada hubungan antara obesitas dengan nilai BPH (p=0,019) dan riwayat diabetes mellitus setelah menggunakan uji Chi-Square, hubungan antara riwayat diabetes mellitus dengan BPH dengan nilai (p = 0,000). Kesimpulan. Ada hubungan antara umur, obesitas dan riwayat diabetes mellitus dengan kejadian BPH.

Holmium laser enucleation of the prostate in benign prostate hyperplasia patients with or without oral antithrombotic drugs: a meta-analysis

2019 ◽  
Vol 51 (12) ◽  
pp. 2127-2136 ◽  
Author(s):  
Xiaonan Zheng ◽  
Liao Peng ◽  
Dehong Cao ◽  
Xin Han ◽  
Hang Xu ◽  
...  
Keyword(s):  
Benign Prostate Hyperplasia ◽  
Meta Analysis ◽  
Holmium Laser ◽  
Antithrombotic Drugs ◽  
Prostate Hyperplasia ◽  
Laser Enucleation ◽  
Benign Prostate ◽  
Holmium Laser Enucleation

scholarly journals PIH13 Consumption of Drugs for the Treatment of Benign Prostate Hyperplasia in Ukraine Compared to the Baltic Countries

2020 ◽  
Vol 23 ◽  
pp. S541
Author(s):  
L. Iakovlieva ◽  
O. Tkachova ◽  
N. Bezditko ◽  
O. Gerasymova ◽  
T. Bahlai ◽  
...  
Keyword(s):  
Benign Prostate Hyperplasia ◽  
Prostate Hyperplasia ◽  
Baltic Countries ◽  
The Baltic ◽  
Benign Prostate
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