Perioperative thromboprophylaxis: inconsistent guidelines and evidence gaps lead to variable practice

2020 ◽  
Vol 90 (12) ◽  
pp. 2391-2392
Author(s):  
Douglas Stupart ◽  
David Watters
Keyword(s):  

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
N Ayoub ◽  
Y Tryliskyy ◽  
M K Baig

Abstract Introduction Several studies have shown benefit from use of preoperative antibiotics in reducing postoperative infection after appendectomy as well as efficacy of postoperative antibiotics in complicated appendicitis (defined as perforated appendix or presence of pus in peritoneum). While for uncomplicated appendicitis, several studies showed no benefit from antibiotics postoperatively but there are no clear NICE guidelines till now and so surgeons have different practice based on their preferences. Method This study included patients who had appendectomy for uncomplicated appendicitis in Worthing hospital from 1st July 2019 till 30th June 2020. The end point was 30-day follow up postoperatively for wound infection or collection. Results 90 patients were admitted with uncomplicated appendicitis with age 6-80 years (mean of 31.3). 46 patients (51%) did not receive postoperative antibiotics (group A) and 44 (49%) received postoperative antibiotics (group B) with a variable practice from one dose to 8-day course. postoperatively, only 1 patient (2.1%) in group A developed wound infection requiring drainage while none in group B developed complications (p-value=1). Conclusions Administration of postoperative antibiotics in uncomplicated appendicitis showed no superiority over non-administration. in addition, they add extra cost on NHS. So, their routine use postoperatively is not recommended, however, larger studies are required to confirm this.





1999 ◽  
Vol 17 (5) ◽  
pp. 357-367 ◽  
Author(s):  
JOAN N. VICKERS ◽  
LORI F. LIVINGSTON ◽  
SHERI UMERIS-BOHNERT ◽  
DEAN HOLDEN


2021 ◽  
Vol 15 (5) ◽  
pp. 333-341
Author(s):  
Guilherme M. Lage ◽  
Lidiane A. Fernandes ◽  
Tércio Apolinário-Souza ◽  
Nathálya G. H. M. Nogueira ◽  
Bárbara P. Ferreira

Background: The benefits of variable practice in motor learning have been traditionally explained by the increased demand for memory processes induced by trial-to-trial changes. Recently, a new perspective associating increased demand for perception with variable practice has emerged. Aim: This revision aims to present and discuss the findings in this exciting topic newly opened. Results / Interpretation: In the second half of 2010’s, a number of studies have pointed out differences in perceptual processing when compared variable and repetitive practices. Different levels of (a) hemodynamic activation, (b) electroencephalographic activity, (c) neurochemical activity, and (d) oculomotor behavior have provided evidence that perceptual processes are affected differently by variable and repetitive practices.



2021 ◽  
Author(s):  
Orit Herzberg ◽  
Katelyn K. Fletcher ◽  
Jacob L. Schatz ◽  
Karen E. Adolph ◽  
Catherine S. Tamis‐LeMonda


2019 ◽  
Vol 109 (3) ◽  
pp. 505-510 ◽  
Author(s):  
Sadaf Bhayat ◽  
Avineet Kaur ◽  
Irnthu Premadeva ◽  
Peter Reynolds ◽  
Harsha Gowda


2017 ◽  
Vol 235 (9) ◽  
pp. 2829-2841 ◽  
Author(s):  
Jacob W. Hinkel-Lipsker ◽  
Michael E. Hahn


Author(s):  
Stanisław H. Czyż ◽  
Martin Zvonař ◽  
Zbigniew Borysiuk ◽  
Jiří Nykodým ◽  
Piotr Oleśniewicz

There are a limited number of studies focusing on the mechanisms explaining why variable practice gives an advantage in a novel situation and constant practice in performance in trained conditions. We hypothesized that this may be due to the different gaze behavior that is developed under different conditions. Twenty participants, randomly assigned to two different groups, practiced basketball free throws for three consecutive days, performing 100 throws per day. The constant group (n = 10) practiced at a free throw distance (4.57 m) only. The variable practice group (n = 10) randomly performed 20 shots per five throw distances (3.35, 3.96, 4.57, 5.18, and 5.79 m) on each day, also accumulating 100 shots per day. We analyzed the total gaze fixation duration, a number of fixations, and the average fixation duration on a basketball rim in a pretest and posttest at the 4.57 m distance. We computed a linear mixed model with test (pretest–posttest), group (constant–variable), and test × group interaction in order to analyze the total fixation duration and number of fixations. The average fixation duration was analyzed with a repeated measure two-way ANOVA, with practice conditions as a between-participants factor and test type as a within-participants factor. We found that the total fixation duration increased significantly in the posttest, regardless of the practice conditions (p < 0.001, effect size = 0.504). The number of fixations also increased significantly in the posttest (p = 0.037, effect size = 0.246). The average fixation duration increased in both groups; however, insignificantly. We also did not find any significant differences between groups. Our results suggest that variable and constant practice conditions may lead to the development of similar gaze behavior.



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