Feasibility of MRI to assess differences in ophthalmic artery blood flow rate in normal tension glaucoma and healthy controls

No data are available for the direct effect of C-type natriuretic peptide (CNP) on atrioventricular (AV) conduction in mammalian hearts. Thus we studied the dromotropic effects of CNP-22 injected into the AV node artery in autonomically decentralized hearts in open-chest, anesthetized dogs. CNP decreased AV interval (AV conduction time) in a dose-dependent manner with increase in coronary artery blood flow rate in six anesthetized dogs. Isosorbide dinitrate did not affect AV interval, but it increased coronary artery blood flow rate. A guanylyl cyclase-linked natriuretic peptide receptor antagonist, HS-142–1, inhibited the decreases in AV interval and the increases in coronary blood flow rate in response to CNP, whereas propranolol did not affect the positive dromotropic response to CNP. These results demonstrate that CNP decreases AV interval and increases coronary artery blood flow rate mediated by a guanylyl cyclase-linked natriuretic peptide receptor, but not β-adrenoceptor, in the dog heart.

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The changes in ovarian hormone levels and ovarian artery blood flow rate after laparoscopic tubal sterilization

European Journal of Obstetrics & Gynecology and Reproductive Biology ◽

10.1016/s0301-2115(01)00410-9 ◽

2001 ◽

Vol 99 (2) ◽

pp. 219-221 ◽

Cited By ~ 19

Author(s):

M. Bulent Tiras ◽

Volkan Noyan ◽

Hakan Ozdemir ◽

Haldun Guner ◽

Akgun Yildiz ◽

...

Keyword(s):

Blood Flow ◽

Flow Rate ◽

Blood Flow Rate ◽

Ovarian Hormone ◽

Artery Blood Flow ◽

Tubal Sterilization ◽

Ovarian Artery ◽

Hormone Levels

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Intraocular Pressure Decrease Does Not Affect Blood Flow Rate of Ophthalmic Artery in Ocular Hypertension

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.61.12.17 ◽

2020 ◽

Vol 61 (12) ◽

pp. 17

Author(s):

Gauti Jóhannesson ◽

Sara Qvarlander ◽

Anders Wåhlin ◽

Khalid Ambarki ◽

Per Hallberg ◽

...

Keyword(s):

Blood Flow ◽

Intraocular Pressure ◽

Ocular Hypertension ◽

Flow Rate ◽

Ophthalmic Artery ◽

Blood Flow Rate ◽

Pressure Decrease

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Why Does Vascular Access Dysfunction Occur despite Brachial Artery Blood Flow Being Higher than Preset Blood Flow?

Kidney and Dialysis ◽

10.3390/kidneydial2010005 ◽

2022 ◽

Vol 2 (1) ◽

pp. 38-43

Author(s):

Jun-ichi Ono ◽

Takushi Oiwa ◽

Yasuo Ogasawara ◽

Seiichi Mochizuki

Keyword(s):

Blood Flow ◽

Flow Rate ◽

Vascular Access ◽

Brachial Artery ◽

Pure Water ◽

Blood Flow Rate ◽

Path Model ◽

Artery Blood Flow ◽

Recirculation Rate ◽

Model Fluid

Background: In recent years, many reports have investigated the usefulness of brachial artery blood flow (BAF) measured by ultrasonography as an evaluation index for the vascular access (VA) stenosis of hemodialysis patients. However, the mechanism of VA dysfunction, despite BAF being higher than the preset blood flow, has not been clarified to date. Methods: The relationship between actual blood-removal flow and recirculation rate with decreasing VA flow was examined using a VA flow path model and pure water as a model fluid. The blood-flow rate was set at 180 mL/min, and the set VA flow rate was lowered stepwise from 350 to 50 mL/min. VA flow rate, blood-removal flow rate, and flow waveform measured between two needle-puncture sites were recorded, and then the actual blood-removal flow rate and recirculation rate were calculated. Results: Recirculation was observed at a VA flow rate < 300 mL/min. The recirculation was due to the VA flow rate, which was transiently reduced to the level below the blood-removal flow rate, resulting in backflow. In contrast, no decrease in the actual blood-removal flow rate was observed. Conclusion: It is suggested that the mechanism of the VA dysfunction, despite the BAF being higher than the preset blood-flow rate, was due to the diastolic BAF being lower than the blood-removal flow rate.

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Blood flow rate during orthostatic pressure changes in the pulp skin of the first toe

European Journal of Vascular and Endovascular Surgery ◽

10.1016/s1078-5884(97)80099-8 ◽

1997 ◽

Vol 13 (3) ◽

pp. 278-284 ◽

Cited By ~ 15

Author(s):

M. Midttun ◽

P. Sejrsen ◽

W.P. Paaske

Keyword(s):

Blood Flow ◽

Flow Rate ◽

Blood Flow Rate ◽

Pressure Changes

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The Effect of Furosemide on the Intrarenal Blood Flow Distribution in the Dog

Canadian Journal of Physiology and Pharmacology ◽

10.1139/y72-113 ◽

1972 ◽

Vol 50 (8) ◽

pp. 774-783 ◽

Cited By ~ 4

Author(s):

Serge Carrière ◽

Michel Desrosiers ◽

Jacques Friborg ◽

Michèle Gagnan Brunette

Keyword(s):

Blood Flow ◽

Flow Rate ◽

Urine Volume ◽

Flow Distribution ◽

Blood Flow Rate ◽

Initial Distribution ◽

Blood Flow Distribution ◽

Intrarenal Blood Flow ◽

Femoral Blood ◽

Furosemide Administration

Furosemide (40 μg/min) was perfused directly into the renal artery of dogs in whom the femoral blood pressure was reduced (80 mm Hg) by aortic clamping above the renal arteries. This maneuver, which does not influence the intrarenal blood flow distribution, produced significant decreases of the urine volume, natriuresis, Ccreat, and CPAH, and prevented the marked diuresis normally produced by furosemide. Therefore the chances that systemic physiological changes occurred, secondary to large fluid movements, were minimized. In those conditions, however, furosemide produced a significant increase of the urine output and sodium excretion in the experimental kidney whereas Ccreat and CPAH were not affected. The outer cortical blood flow rate (ml/100 g-min) was modified neither by aortic constriction (562 ± 68 versus 569 ± 83) nor by the subsequent administration of furosemide (424 ± 70). The blood flow rate of the outer medulla in these three conditions remained unchanged (147 ± 52 versus 171 ± 44 versus 159 ± 54). The initial distribution of the radioactivity in each compartment remained comparable in the three conditions. In parallel with the results from the krypton-85 disappearance curves, the autoradiograms, silicone rubber casts, and EPAH did not suggest any change in the renal blood flow distribution secondary to furosemide administration.

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The Effect of Hematocrit on the Clearance of Small Molecules during Hemodialysis

The International Journal of Artificial Organs ◽

10.1177/039139888300600308 ◽

1983 ◽

Vol 6 (3) ◽

pp. 127-130 ◽

Cited By ~ 5

Author(s):

C. Woffindin ◽

N.A. Hoenich ◽

D.N.S. Kerr

Keyword(s):

Blood Flow ◽

Regression Analysis ◽

Small Molecules ◽

Flat Plate ◽

Flow Rate ◽

Distribution Curve ◽

Blood Flow Rate ◽

Hollow Fibre ◽

Urea Clearance ◽

Flow Rates

Data collected during the evaluation of a series of hemodialysers were analysed to see the effect of hematocrit on the clearance of urea and creatinine. All evaluations were performed on patients with a range of hematocrits with a mean close to 20%. The urea clearance of those in the upper half of the distribution curve (mean hematocrit 29.4%) was not significantly different from that of patients in the lower half of the distribution curve (mean hematocrit 16.9%) whether the clearance was studied at high or low blood flow rates and with hollow fibre or flat plate disposable hemodialysers. Likewise, there was no correlation between hematocrit and urea clearance by regression analysis. In contrast, the clearance of creatinine was affected by hematocrit being greater at lower hematocrit values. This difference was independent of blood flow rate and dialyser type and was confirmed by regression analysis.

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