scholarly journals Systematic review: psychological morbidity in young people with inflammatory bowel disease - risk factors and impacts

2016 ◽  
Vol 44 (1) ◽  
pp. 3-15 ◽  
Author(s):  
A. J. Brooks ◽  
G. Rowse ◽  
A. Ryder ◽  
E. J. Peach ◽  
B. M. Corfe ◽  
...  
2016 ◽  
Vol 44 (4) ◽  
pp. 426-426
Author(s):  
A. J. Brooks ◽  
G. Rowse ◽  
A. Ryder ◽  
E. J. Peach ◽  
B. M. Corfe ◽  
...  

2021 ◽  
Vol 32 (6) ◽  
pp. 508-518
Author(s):  
Shanzhen Shi ◽  
◽  
Jiaxing Feng ◽  
Lixiang Zhou ◽  
Yu Li ◽  
...  

2015 ◽  
Vol 10 (3) ◽  
pp. 306-314 ◽  
Author(s):  
Roxana Zaharie ◽  
Alina Tantau ◽  
Florin Zaharie ◽  
Marcel Tantau ◽  
Liana Gheorghe ◽  
...  

2018 ◽  
Vol 12 (supplement_1) ◽  
pp. S078-S078
Author(s):  
R T Lees ◽  
A J Brooks ◽  
G Rowse ◽  
P Narula ◽  
P Norman ◽  
...  

2020 ◽  
pp. flgastro-2019-101353
Author(s):  
Anna B Hoogkamer ◽  
Alenka J Brooks ◽  
Georgina Rowse ◽  
Alan J Lobo

BackgroundPsychological morbidity in inflammatory bowel disease is common with significant impact on quality of life and health outcomes, but factors which predict the development of psychological morbidity are unclear.AimTo undertake a systematic literature review of the predictors of psychological morbidity in patients with inflammatory bowel disease.MethodsElectronic searches for English-language articles were performed with keywords relating to psychological morbidity according to the Diagnostic and Statistical Manual of Mental Disorders IV and subsequent criteria, and inflammatory bowel disease; in MEDLINE, PsychInfo, Web of Science and EMBASE for studies published from January 1997 to 25 January 2019.ResultsOf 660 studies identified, seven met the inclusion criteria. All measured depression, with three also measuring anxiety. Follow-up duration was variable (median of 18 months range 6–96 months). Risk factors identified for development of psychological morbidity included physical factors: aggressive disease (HR 5.77, 95% CI 1.89 to 17.7) and greater comorbidity burden (OR 4.31, 95% CI 2.83 to 6.57) and psychological risk factors: degree of gratitude (r=−0.43, p<0.01) and parenting stress (R-change=0.03, F(1,58)=35.6, p<0.05). Age-specific risk was identified with young people (13–17 years) at increased risk.ConclusionsIdentifiable risks for the development of psychological morbidity in inflammatory bowel disease include physical and psychological factors. Further research is required from large prospective studies to enable early interventions in those at risk and reduce the impact of psychological morbidity.


2019 ◽  
Vol 13 (8) ◽  
pp. 1003-1011 ◽  
Author(s):  
Alenka J Brooks ◽  
Paul Norman ◽  
Emily J Peach ◽  
Anna Ryder ◽  
Alexander J Scott ◽  
...  

Abstract Background and Aims Psychological morbidity is increased in young people with inflammatory bowel disease [IBD]. Illness perceptions may be an important factor. This study aimed to describe the prevalence and severity of psychological morbidity and to examine relationships between baseline illness perceptions and anxiety, depression, and health-related quality of life [HRQoL], at baseline and 12 months later, in 16–21 year olds with IBD. Methods IBD patients [n = 121] completed measures of anxiety, depression, HRQoL, and illness perceptions [IPQ-R] at baseline and follow-up [n = 100, 83%]. Results Among the 121 patients at baseline [median age 19.3 years, 40% female, 62% Crohn’s disease, 73% in clinical remission], 55% reported elevated symptoms of anxiety/depression and 83% reported low HRQoL. Negative illness perceptions at baseline were significantly correlated with greater anxiety, depression, and lower HRQoL at baseline and follow-up. In regression analysis at baseline, the IPQ-R domain of greater perception of a cyclical nature of IBD was an independent predictor of anxiety, and a greater perceived emotional impact of IBD was an independent predictor of anxiety, depression, and HRQoL. Female gender and clinical relapse were also independent predictors of lower HRQoL. After controlling for baseline measures, clinical risk factors and illness perceptions did not explain additional variance in psychological morbidity at follow-up. Conclusions A high prevalence of psychological morbidity, stable over 1 year, was demonstrated in young people with IBD. Having negative illness perceptions, being female, and having active disease predicted those at greatest risk of psychological morbidity. Illness perceptions may be an appropriate target for psychological interventions.


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