The use of tissue‐engineered skin to demonstrate the negative effect of CXCL5 on epidermal ultraviolet radiation‐induced cyclobutane pyrimidine dimer repair efficiency

2020 ◽  
Author(s):  
M.M. Dorr ◽  
R. Guignard ◽  
F.A. Auger ◽  
P.J. Rochette
Keyword(s):  
Ultraviolet Radiation ◽  
Pyrimidine Dimer ◽  
Cyclobutane Pyrimidine Dimer ◽  
Repair Efficiency ◽  
Negative Effect ◽  
Radiation Induced

scholarly journals The Roles of Several Residues ofEscherichia coliDNA Photolyase in the Highly Efficient Photo-Repair of Cyclobutane Pyrimidine Dimers

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Lei Xu ◽  
Guoping Zhu
Keyword(s):  
Escherichia Coli ◽  
Energy Source ◽  
Pyrimidine Dimer ◽  
Cyclobutane Pyrimidine Dimer ◽  
Model Compounds ◽  
Cyclobutane Pyrimidine Dimers ◽  
Dna Photolyase ◽  
Pyrimidine Dimers ◽  
Repair Efficiency ◽  
Very High

Escherichia coliDNA photolyase is an enzyme that repairs the major kind of UV-induced lesions, cyclobutane pyrimidine dimer (CPD) in DNA utilizing 350–450 nm light as energy source. The enzyme has very high photo-repair efficiency (the quantum yield of the reaction is ~0.85), which is significantly greater than many model compounds that mimic photolyase. This suggests that some residues of the protein play important roles in the photo-repair of CPD. In this paper, we have focused on several residues discussed their roles in catalysis by reviewing the existing literature and some hypotheses.

scholarly journals Cyclobutane Pyrimidine Dimer Density as a Predictive Biomarker of the Biological Effects of Ultraviolet Radiation in Normal Human Fibroblast

2013 ◽  
Vol 90 (1) ◽  
pp. 145-154 ◽  
Author(s):  
Christopher D. Sproul ◽  
David L. Mitchell ◽  
Shangbang Rao ◽  
Joseph G. Ibrahim ◽  
William K. Kaufmann ◽  
...  
Keyword(s):  
Ultraviolet Radiation ◽  
Human Fibroblast ◽  
Biological Effects ◽  
Predictive Biomarker ◽  
Pyrimidine Dimer ◽  
Normal Human Fibroblast ◽  
Cyclobutane Pyrimidine Dimer ◽  
Normal Human
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