scholarly journals The novel H2 S donor 4-carboxy-phenyl isothiocyanate inhibits mast cell degranulation and renin release by decreasing intracellular calcium

2016 ◽  
Vol 173 (22) ◽  
pp. 3222-3234 ◽  
Author(s):  
Alice Marino ◽  
Alma Martelli ◽  
Valentina Citi ◽  
Ming Fu ◽  
Rui Wang ◽  
...  
Keyword(s):  
Mast Cell ◽  
Intracellular Calcium ◽  
Mast Cell Degranulation ◽  
Renin Release ◽  
Phenyl Isothiocyanate ◽  
The Novel

Mast cell degranulation mediates bronchoconstriction via serotonin and not via renin release

2010 ◽  
Vol 640 (1-3) ◽  
pp. 185-189 ◽  
Author(s):  
Manne Krop ◽  
Zeynep G. Özünal ◽  
Wenxia Chai ◽  
René de Vries ◽  
Durk Fekkes ◽  
...  
Keyword(s):  
Mast Cell ◽  
Mast Cell Degranulation ◽  
Renin Release

scholarly journals Nerve growth factor induces mast cell degranulation without changing intracellular calcium levels

FEBS Letters ◽  
1986 ◽  
Vol 198 (2) ◽  
pp. 315-320 ◽  
Author(s):  
N. Mazurek ◽  
G. Weskamp ◽  
P. Erne ◽  
U. Otten
Keyword(s):  
Mast Cell ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Intracellular Calcium ◽  
Mast Cell Degranulation ◽  
Nerve Growth

scholarly journals Human mast cell degranulation is distinguished from selective secretion of TNF through intracellular calcium, energy and mitochondrial morphology dynamics

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Bodi Zhang ◽  
Asimenia Angelidou ◽  
Konstantinos‐Dionysios Alysandratos ◽  
Michael Tagen ◽  
Duraisamy Kempuraj ◽  
...  
Keyword(s):  
Mast Cell ◽  
Intracellular Calcium ◽  
Mast Cell Degranulation ◽  
Human Mast Cell ◽  
Mitochondrial Morphology

Mast Cell Degranulation with Special Reference to the Effect of Lipid Administration upon the Mesenteric Mast Cell of Albino Rats

1968 ◽  
Vol 9 (2) ◽  
pp. 100
Author(s):  
Kook Lee ◽  
Yong Hae Lee ◽  
Soo Yun Pak
Keyword(s):  
Mast Cell ◽  
Special Reference ◽  
Mast Cell Degranulation ◽  
Albino Rats

Mode of Mast Cell Degranulation

1971 ◽  
Vol 33 (3) ◽  
pp. 223-228
Author(s):  
Shojiro MORIYASU
Keyword(s):  
Mast Cell ◽  
Mast Cell Degranulation

Transcutaneous systemic photobiomodulation reduced lung inflammation in experimental model of asthma by altering the mast cell degranulation and interleukin 10 level

2021 ◽  
Author(s):  
Paula Tatiane Alonso ◽  
Adriana Schapochnik ◽  
Simone Klein ◽  
Robson Brochetti ◽  
Amílcar Sabino Damazo ◽  
...  
Keyword(s):  
Mast Cell ◽  
Experimental Model ◽  
Lung Inflammation ◽  
Interleukin 10 ◽  
Mast Cell Degranulation

scholarly journals Platelet and Erythrocyte Extravasation across Inflamed Corneal Venules Depend on CD18, Neutrophils and Mast Cell Degranulation

2021 ◽  
Vol 22 (14) ◽  
pp. 7360
Author(s):  
Angie De La Cruz ◽  
Aubrey Hargrave ◽  
Sri Magadi ◽  
Justin A. Courson ◽  
Paul T. Landry ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Types ◽  
Mast Cell Degranulation ◽  
Wild Type ◽  
Delayed Wound Healing ◽  
Corneal Epithelial ◽  
Corneal Abrasion ◽  
Low Levels ◽  
Endothelial Pores

Platelet extravasation during inflammation is under-appreciated. In wild-type (WT) mice, a central corneal epithelial abrasion initiates neutrophil (PMN) and platelet extravasation from peripheral limbal venules. The same injury in mice expressing low levels of the β2-integrin, CD18 (CD18hypo mice) shows reduced platelet extravasation with PMN extravasation apparently unaffected. To better define the role of CD18 on platelet extravasation, we focused on two relevant cell types expressing CD18: PMNs and mast cells. Following corneal abrasion in WT mice, we observed not only extravasated PMNs and platelets but also extravasated erythrocytes (RBCs). Ultrastructural observations of engorged limbal venules showed platelets and RBCs passing through endothelial pores. In contrast, injured CD18hypo mice showed significantly less venule engorgement and markedly reduced platelet and RBC extravasation; mast cell degranulation was also reduced compared to WT mice. Corneal abrasion in mast cell-deficient (KitW-sh/W-sh) mice showed less venule engorgement, delayed PMN extravasation, reduced platelet and RBC extravasation and delayed wound healing compared to WT mice. Finally, antibody-induced depletion of circulating PMNs prior to corneal abrasion reduced mast cell degranulation, venule engorgement, and extravasation of PMNs, platelets, and RBCs. In summary, in the injured cornea, platelet and RBC extravasation depends on CD18, PMNs, and mast cell degranulation.

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