Intensive monitoring of adverse drug events associated with the use of new glucose‐lowering drugs: results from an inception cohort study in Portugal

2019 ◽  
Vol 37 (4) ◽  
pp. 648-656 ◽  
Author(s):  
C. Torre ◽  
J. Guerreiro ◽  
P. Longo ◽  
J. F. Raposo ◽  
H. Leufkens ◽  
...  
Keyword(s):  
Cohort Study ◽  
Adverse Drug Events ◽  
Inception Cohort ◽  
Glucose Lowering ◽  
Intensive Monitoring

scholarly journals Effect of different methods for estimating persistence and adherence to new glucose-lowering drugs: results of an observational, inception cohort study in Portugal

2018 ◽  
Vol Volume 12 ◽  
pp. 1471-1482 ◽  
Author(s):  
Carla Torre ◽  
Jose Guerreiro ◽  
Patricia Longo ◽  
Joao Filipe Raposo ◽  
Hubert Leufkens ◽  
...  
Keyword(s):  
Cohort Study ◽  
Inception Cohort ◽  
Glucose Lowering

scholarly journals Treatment with a DPP-4 inhibitor at time of hospital admission for COVID-19 is not associated with improved clinical outcomes: data from the COVID-PREDICT cohort study in The Netherlands

2021 ◽  
Author(s):  
Rick I. Meijer ◽  
Trynke Hoekstra ◽  
Niels C. Gritters van den Oever ◽  
Suat Simsek ◽  
Joop P. van den Bergh ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Hospital Admission ◽  
Clinical Outcomes ◽  
Primary Outcome ◽  
Infectious Complications ◽  
Glucose Lowering ◽  
Diabetes Severity ◽  
Outcome Mortality

Abstract Purpose Inhibition of dipeptidyl peptidase (DPP-)4 could reduce coronavirus disease 2019 (COVID-19) severity by reducing inflammation and enhancing tissue repair beyond glucose lowering. We aimed to assess this in a prospective cohort study. Methods We studied in 565 patients with type 2 diabetes in the CovidPredict Clinical Course Cohort whether use of a DPP-4 inhibitor prior to hospital admission due to COVID-19 was associated with improved clinical outcomes. Using crude analyses and propensity score matching (on age, sex and BMI), 28 patients using a DPP-4 inhibitor were identified and compared to non-users. Results No differences were found in the primary outcome mortality (matched-analysis = odds-ratio: 0,94 [95% confidence interval: 0,69 – 1,28], p-value: 0,689) or any of the secondary outcomes (ICU admission, invasive ventilation, thrombotic events or infectious complications). Additional analyses comparing users of DPP-4 inhibitors with subgroups of non-users (subgroup 1: users of metformin and sulphonylurea; subgroup 2: users of any insulin combination), allowing to correct for diabetes severity, did not yield different results. Conclusions We conclude that outpatient use of a DPP-4 inhibitor does not affect the clinical outcomes of patients with type 2 diabetes who are hospitalized because of COVID-19 infection.

scholarly journals Do ventilatory parameters influence outcome in patients with severe acute respiratory infection? Secondary analysis of an international, multicentre14-day inception cohort study

2021 ◽  
Vol 66 ◽  
pp. 78-85
Author(s):  
Yasser Sakr ◽  
Thais Midega ◽  
Julia Antoniazzi ◽  
Jordi Solé-Violán ◽  
Philippe R. Bauer ◽  
...  
Keyword(s):  
Cohort Study ◽  
Respiratory Infection ◽  
Acute Respiratory Infection ◽  
Secondary Analysis ◽  
Inception Cohort ◽  
Ventilatory Parameters ◽  
Severe Acute Respiratory Infection

TRAJECTORIES OF HEALTH SYSTEM USE AND SURVIVAL FOR COMMUNITY-DWELLING PERSONS WITH DEMENTIA: AN INCEPTION COHORT STUDY

2019 ◽  
Vol 15 (7) ◽  
pp. P1635-P1636
Author(s):  
Susan E. Bronskill ◽  
Laura C. Maclagan ◽  
Jennifer Walker ◽  
Jun Guan ◽  
Xuesong Wang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Health System ◽  
Community Dwelling ◽  
Inception Cohort ◽  
System Use

Fear of Movement/(Re)Injury Predicting Chronic Disabling Low Back Pain: A Prospective Inception Cohort Study

Spine ◽  
2006 ◽  
Vol 31 (6) ◽  
pp. 658-664 ◽  
Author(s):  
Ilse E. J. Swinkels-Meewisse ◽  
Jeffrey Roelofs ◽  
Erik G. W. Schouten ◽  
André L. M. Verbeek ◽  
Rob A. B. Oostendorp ◽  
...  
Keyword(s):  
Cohort Study ◽  
Low Back Pain ◽  
Back Pain ◽  
Low Back ◽  
Inception Cohort ◽  
Fear Of Movement

Early glycaemic control among patients with type 2 diabetes and initial glucose-lowering treatment: a 13-year population-based cohort study

2015 ◽  
Vol 17 (8) ◽  
pp. 771-780 ◽  
Author(s):  
R. W. Thomsen ◽  
L. M. Baggesen ◽  
E. Svensson ◽  
L. Pedersen ◽  
H. Nørrelund ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Glycaemic Control ◽  
Population Based ◽  
Glucose Lowering
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