The incidence, risk and functional outcomes of intracranial haemorrhage in children with inherited bleeding disorders at one haemophilia center

Haemophilia ◽  
2016 ◽  
Vol 22 (4) ◽  
pp. 556-563 ◽  
Author(s):  
M. Bladen ◽  
E. Main ◽  
K. Khair ◽  
N. Hubert ◽  
E. Koutoumanou ◽  
...  
Keyword(s):  
Functional Outcomes ◽  
Intracranial Haemorrhage ◽  
Bleeding Disorders ◽  
Incidence Risk

The incidence, risk and functional outcomes of intracranial haemorrhage in children with inherited bleeding disorders

Physiotherapy ◽  
2015 ◽  
Vol 101 ◽  
pp. e930-e931
Author(s):  
M. Bladen ◽  
K. Khair ◽  
E. Koutoumanou ◽  
R. Leisner ◽  
N. Hubert ◽  
...  
Keyword(s):  
Functional Outcomes ◽  
Intracranial Haemorrhage ◽  
Bleeding Disorders ◽  
Incidence Risk

scholarly journals Intracranial haemorrhage in children with inherited bleeding disorders in the UK 2003-2015: A national cohort study

Haemophilia ◽  
2018 ◽  
Vol 24 (4) ◽  
pp. 641-647 ◽  
Author(s):  
E. A. Chalmers ◽  
J. Alamelu ◽  
P. W. Collins ◽  
M. Mathias ◽  
J. Payne ◽  
...  
Keyword(s):  
Cohort Study ◽  
Intracranial Haemorrhage ◽  
Bleeding Disorders ◽  
National Cohort ◽  
The Uk

scholarly journals Delirium in Covid-19 Patients: Incidence, Risk Factors and Early Outcomes.

2021 ◽  
Author(s):  
Jorge Humberto Mejia-Mantilla ◽  
Andrés Gempeler ◽  
Leidy K Gaviria ◽  
Pablo Amaya ◽  
Jose Luis Aldana ◽  
...  
Keyword(s):  
Risk Factors ◽  
Mechanical Ventilation ◽  
Multivariate Analysis ◽  
Functional Outcomes ◽  
Patient Characteristics ◽  
Frequent Event ◽  
High Incidence ◽  
Incidence Risk ◽  
Prolonged Icu Stay ◽  
The Impact

Abstract Background Delirium is a frequent event in severely ill patients; its incidence and prevalence varies depending on several factors; Covid has been associated to high incidence of delirium leading to speculation of specific mechanisms of neurotoxicity by the SARS-CoV-2. We present the analysis of risk factors for delirium incidence and the impact of delirium in the functional outcomes. Methods We included patients admitted to a referral center in Cali, Colombia between April and August 2020. Patients were evaluated for demographics, severity of disease, comorbidities, clinical outcomes, delirium and survival at discharge. We evaluated the association of patient characteristics and disease factors with delirium incidence by multivariate analysis (Hosmer and Lemeshow) and the associations of delirium with functional outcome at discharge Results Among 333 patients, 58 (17.42%. 95% CI: 13.62–21.77%) presented delirium 16 (IQR: 11 − 20) days after symptom onset. Patients with delirium were older, reported muscular weakness more often, had a higher NEWS2 score at admission, and had more comorbidities (mainly Diabetes Mellitus II). Multivariate analysis of hospitalization events and treatments found mechanical ventilation as the only significant covariate. The association between need for mechanical ventilation and delirium development was estimated at OR = 11.72, (95%CI = 4.16–34.23). Patients who developed delirium had a higher frequency of functional impairment: mRs > 2 (70.7% vs 24.7%, p < 0.001) and had a prolonged ICU stay (median 13 days, IQR 8–21 vs median 5, IQR 3–10 days, p < 0.0001) compared to patients without delirium. Conclusion Our data show that premorbid functional status, the severity of respiratory disfunction and the presence of inflammatory markers are determinant in the risk of delirium; we believe that delirium might not be specially related to SARS-CoV-2 infections, its high frequency during this pandemic could be the result of concurring factors shared between critically-ill patients and severe COVID-19 patients. Further research is granted to clarify this aspect

Radionuclide synovectomy/synoviorthesis (RS) in patients with bleeding disorders: A review of patient and procedure demographics and functional outcomes in the ATHNdataset

Haemophilia ◽  
2017 ◽  
Vol 23 (6) ◽  
pp. 926-933 ◽  
Author(s):  
C. McGuinn ◽  
D. Cheng ◽  
D. Aschman ◽  
S. L. Carpenter ◽  
R. Sidonio ◽  
...  
Keyword(s):  
Functional Outcomes ◽  
Bleeding Disorders ◽  
Radionuclide Synovectomy

Abstract TMP9: Use of Immediate Dual Antiplatelet Therapy in Carotid Stenting for Tandem Occlusion Stroke is Associated With Acceptable Symptomatic Intracranial Haemorrhage Rates

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Fiona S Lau ◽  
Amer Mitchelle ◽  
Andrew Cheung ◽  
Jason Wenderoth ◽  
Cecilia Cappelen-Smith ◽  
...  
Keyword(s):  
Antiplatelet Therapy ◽  
Functional Outcomes ◽  
Intracranial Haemorrhage ◽  
Dual Antiplatelet Therapy ◽  
Carotid Stenting ◽  
Anterior Circulation ◽  
Stent Patency ◽  
Stroke Study ◽  
Tandem Occlusion ◽  
Acute Stent Thrombosis

Introduction: Observational studies have shown conflicting data on safety and efficacy of carotid stenting in the setting of acute ischemic stroke. We evaluated our stent patency, functional outcomes and symptomatic intracranial haemorrhage rates in acute strokes with tandem occlusions treated with endovascular thrombectomy and concurrent carotid stenting. Methods: Prospectively maintained EVT databases at two comprehensive stroke centres were interrogated for patients with anterior circulation tandem occlusion stroke who were treated with EVT and extracranial carotid artery stenting. Intracranial haemorrhage on post-operative CT & MRI brain was assessed on European Cooperative Acute Stroke Study II criteria. Stent patency was assessed on CTA 12-24 hours post-operatively. Clinical and neuroimaging endpoints were modified treatment in cerebral ischaemia (mTICI) score, stent patency, any intracranial haemorrhage, symptomatic intracranial haemorrhage (sICH), and 90-day modified Rankin Scale (mRS). Results: Between 2016 and 2019, 105 patients were identified (mean age 70 years, 78% male, median NIHSS 15). Median time to reperfusion was 9.26 hours, with 97.1% achieving mTICI 2b/3. Immediate dual antiplatelet therapy was used in 102 (97.1%) patients. Good functional outcomes (mRS 0-2) were achieved in 53 (51%) patients. Acute stent thrombosis occurred in 12 (11.4%) patients with 7 (58.3%) still achieving good functional outcomes. Any intracranial haemorrhage occurred in 46 (44%) of all patients. Symptomatic intracranial haemorrhage occurred in 8 (7.6%). All sICH patients had 90-day mRS of 3-6. Conclusion: Acute tandem occlusion stroke patients present complex management challenges. Despite immediate dual antiplatelet therapy, acute stent occlusions may still occur. Symptomatic intracranial haemorrhage rates are acceptable in these complex patients, however, all patients with sICH had poorer outcomes.

scholarly journals Risk of traumatic intracranial haemorrhage in children with bleeding disorders

2020 ◽  
Vol 56 (12) ◽  
pp. 1891-1897
Author(s):  
Silvia Bressan ◽  
Paul Monagle ◽  
Stuart R Dalziel ◽  
Meredith L Borland ◽  
Natalie Phillips ◽  
...  
Keyword(s):  
Intracranial Haemorrhage ◽  
Bleeding Disorders

An unusual cause of stridor in a neonate

1994 ◽  
Vol 108 (1) ◽  
pp. 63-64 ◽  
Author(s):  
Koh Kwong Fah ◽  
Henry K. K. Tan
Keyword(s):  
Vocal Fold ◽  
Intracranial Haemorrhage ◽  
Unusual Case ◽  
Haemophilia A ◽  
Bleeding Disorders ◽  
Vocal Fold Palsy

AbstractWe report an unusual case of unilateral vocal fold palsy due to intracranial haemorrhage in a neonate with undiagnosed haemophilia A. Bleeding disorders in neonates are briefly discussed and the importance of a systemic investigation of stridor in children is emphasized.

219: Functional Outcomes and Quality of Life Following Laparoscopic Radical Prostatectomy: Prospective Analysis Over a 4-Year Experience

2006 ◽  
Vol 175 (4S) ◽  
pp. 72-72
Author(s):  
Andrew A. Wagner ◽  
Richard E. Link ◽  
Aron Sulman ◽  
Wendy Sullivan ◽  
Christian P. Pavlovich ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Radical Prostatectomy ◽  
Functional Outcomes ◽  
Laparoscopic Radical Prostatectomy ◽  
Prospective Analysis
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