Quality of life and psychological morbidity in women with polycystic ovary syndrome: body mass index, age and the provision of patient information are significant modifiers

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting 5-10% of women worldwide. It has clinical, hormonal and psychological manifestation like anxiety, depression and low self-esteem. Aim was to evaluate prevalence of anxiety, depression, and quality of life in medical students with PCOS. Objectives were to study the prevalence of anxiety, depression among medical students suffering from PCOS; and to evaluate quality of life (QoL) in students with PCOS and its association with anxiety, depression and quality of life.Methods: The cross sectional study was conducted among 70 medical students at Geetanjali Medical College and Hospital, Udaipur, Rajasthan, from February 2019 – June 2020. Students were screened and selected as per the Rotterdam’s 2003 criteria after informed consent. Mental health assessment done by using Hamilton depression rating scale for depression, Hamilton anxiety rating scale for anxiety, and using 36-item short form survey for QoL.Results: Twenty five (35.7%) students suffered from anxiety while 20 (28.5%) had depressive disorders. Forty five (64%) patient both anxiety and depression. These students had significant psychological morbidity and poor QoL.Conclusions: Psychological morbidity with PCOS is undertreated and need to be addressed and treated in time so as to turn these students into a responsible happy adult.

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The impact of polycystic ovary syndrome on women’s quality of life: Nursing guidelines for its

Clinical Nursing Studies ◽

10.5430/cns.v7n3p42 ◽

2019 ◽

Vol 7 (3) ◽

pp. 42

Author(s):

Hanan Elzeblawy Hassan ◽

Doaa Shehta Said Farg

Keyword(s):

Quality Of Life ◽

Body Mass Index ◽

Polycystic Ovary Syndrome ◽

Polycystic Ovary ◽

Reproductive Age ◽

Phenotypic Characteristics ◽

Ovary Syndrome ◽

Women's Knowledge ◽

Women’S Knowledge

Background: Polycystic ovary syndrome (PCOS) is an uncertain etiology heterogeneous disorder, which affects 6.0% to 10.0% of women in their reproductive age. Aim: assess phenotypic characteristics of women with PCOS, discovery the association between women’s quality-of-life (QOL) and its occurrence and improve women’s knowledge & increase awareness regarding PCOS.Methods: A descriptive cross-sectional design had been utilized on a purposive sample of 300 women in reproductive age with PCOS in the gynecological outpatient clinic at Beni-Suef General Hospital, Egypt. A structured interviewing schedule, patient’s assessment record, visual-analogue-scale, Ferriman-Gallwey-Evaluation-of-Hirsutism, QOL Questionnaire, Short-Form-Health-Survey (SF-36), and designed intervention nursing-guideline had been used for data collection.Results: A high percentage (56.7%) of women had a complete phenotype characteristics of PCOS. The most prevalent phenotypic characteristics were alopecia (65.0%), irregular menses (58.7%), and obesity/overweight (48.1%). Statistically significant was found between women’s general characteristic of PCOS and their age, body-mass-index, hirsutism, and average cycle length, p < .05. Women’s QOL had affected negatively by PCO Syndrome, p < .05.Conclusions: PCOS is a common risk factor for acne, alopecia, hirsutism. Many factors to be associated with its phenotype as: body-mass-index, hirsutism, and average cycles length. It has a negative impact on phenotype characteristic, psychological/social domain and total QOL scale. The nursing guideline had a crucial role in the improvement of women’s knowledge in allover items of women’s knowledge.Recommendation: Upgrading women’s knowledge concerning PCOS with a periodic screening of women for early detection and management. Health-Promotion-Programs through different media to improve QOL for women with PCOS.

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Metformin treatment with or without life style changes in patients with polycystic ovary syndrome

Orvosi Hetilap ◽

10.1556/oh.2011.29045 ◽

2011 ◽

Vol 152 (16) ◽

pp. 628-632 ◽

Cited By ~ 2

Author(s):

Gyula Petrányi ◽

Mária Zaoura-Petrányi

Keyword(s):

Body Mass Index ◽

Polycystic Ovary Syndrome ◽

Treatment Period ◽

Body Mass ◽

Life Style ◽

Polycystic Ovary ◽

Glycaemic Index ◽

Ovary Syndrome ◽

Waist To Hip Ratio ◽

Life Style Changes

Treatment with metformin three times 500 mg daily had been advised since 2002, to patients suffering from the polycystic ovary syndrome diagnosed by the Rotterdam criteria and who did not want to take contraceptive pills. More recently, life style changes have also been introduced to treatment recommendation: increased physical activity, low glycaemic index diet; also with calorie restriction for the obese patients. Aim: To assess the efficacy of the two treatment forms on clinical symptoms of the disease. Method: The metformin only historical control group (metformin monotherapy) consisted of 27 patients between the ages from 18 to 39 years (mean 29 years); to which was the age-matched metformin and life style changes group (triple basal therapy) of 29 patients compared. The following parameters were registered at the beginning and the end of a six-month treatment period: global acne score, Ferriman-Gallwey hirsutism score, body mass index, waist-to-hip circumference ratio, and menstrual cycles. Results: By the end of the treatment period, both acne and hirsutism scores improved significantly in both treatment groups (P<0.001); the improvements did not differ between them: acne 8.6±5.7 vs. 9.2±5.9 (P = 0.70); hirsutism 2.5±2.0 vs. 2.6±1.6 (P = 0.83). Body mass index and waist-to-hip ratio remained practically unchanged in the metformin only group: 0.26±1.0 kg/m2 (P = 0.21) and 0.001±0.02 (P = 0.71). Body mass index decreased in the triple therapy group by 0.91±1.1 kg/m2 (P<0.001); and waist-to-hip ratio by 0.019±0.03 (P<0.001). The decrease of the body mass index was more remarkable in overweight patients: 1.10±1.26 kg/m2 (P = 0.002) vs. 0.64±0.88 kg/m2 (P = 0.03) in lean patients. Recommendation on life style changes with metformin did not show further improvement of hyperandrogenic symptoms in comparison to metformin alone but the combined therapy diminished body size indexes. Conclusion: Authors recommend the triple basal treatment consisting of metformin, physical exercise and low glycaemic index diet to their patients with polycystic ovary syndrome for assessment of its long-term efficacy. Orv. Hetil., 2011, 152, 628–632.

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