Comparison of endometrial intraepithelial neoplasia with WHO endometrial hyperplasia classification system. A comparative study of 150 cases

2010 ◽  
Vol 57 (4) ◽  
pp. 646-648 ◽  
Author(s):  
Vijay C Popat ◽  
Deval N Vora ◽  
Nilesh S Gadhvi ◽  
Viral M Bhanvadia ◽  
Yogendra G Madan
Keyword(s):  
Comparative Study ◽  
Classification System ◽  
Endometrial Hyperplasia ◽  
Intraepithelial Neoplasia ◽  
System A ◽  
Endometrial Intraepithelial Neoplasia

Endometrial hyperplasia (Clinical lecture)

2016 ◽  
pp. 10-18 ◽  
Author(s):  
I.B. Vovk ◽  
◽  
N.Е. Gorban ◽  
O.Ju. Borysiuk ◽  
◽  
...  
Keyword(s):  
Key Words ◽  
Hormonal Therapy ◽  
Endometrial Hyperplasia ◽  
Intraepithelial Neoplasia ◽  
Diagnosis And Treatment ◽  
Pathogenetic Mechanisms ◽  
Endometrial Intraepithelial Neoplasia ◽  
Mechanisms Of Development ◽  
Clinical Lecture

In clinical lecture presents modern views of endometrial hyperplasia in terms of practitioner gynecologist. The problems of classification, pathogenetic mechanisms of development of endometrial hyperplasia. Particular attention is paid to modern approaches to diagnosis and treatment of endometrial hyperplasia. Key words: hyperplasia, endometrium, classification, endometrial hyperplasia, endometrial intraepithelial neoplasia, hormonal therapy.

Benign Endometrial Hyperplasia Sequence and Endometrial Intraepithelial Neoplasia

2007 ◽  
Vol 26 (2) ◽  
pp. 103-114 ◽  
Author(s):  
George L. Mutter ◽  
Richard J. Zaino ◽  
Jan P.A. Baak ◽  
Rex C. Bentley ◽  
Stanley J. Robboy
Keyword(s):  
Endometrial Hyperplasia ◽  
Intraepithelial Neoplasia ◽  
Endometrial Intraepithelial Neoplasia

scholarly journals MOLECULAR PROFILES OF ENDOMETRIAL HYPERPLASIA AND ENDOMETRIAL INTRAEPITHELIAL NEOPLASIA

2018 ◽  
Vol 14 (2) ◽  
pp. 76-81 ◽  
Author(s):  
S. A. Levakov ◽  
N. A. Sheshukova ◽  
A. G. Kedrova ◽  
A. S. Fedotova ◽  
E. A. Obukhova
Keyword(s):  
Endometrial Hyperplasia ◽  
Intraepithelial Neoplasia ◽  
Control Group ◽  
Tumor Proliferation ◽  
Invasive Growth ◽  
Inhibitors Of Apoptosis ◽  
Endometrial Intraepithelial Neoplasia ◽  
Atypical Cells ◽  
Molecular Profiles

Objective: to assess molecular profiles of endometrial hyperplasia and endometrial intraepithelial neoplasia.Materials and methods. We conducted a retrospective study that included 77 patients with a morphologically verified hyperplastic process in the endometrium. Of them, 34 patients had endometrial hyperplasia and 33 patients had endometrial intraepithelial neoplasia. The control group comprised 30 women with no endometrial disorders according to the results of histological examination.Results. Patients with endometrial intraepithelial neoplasia are at high risk of developing cancer. High angiogenic activity, pronounced vascularization, and endometrial hypoxia are believed to be important risk factors contributing to tumor proliferation and transformation. The expression of inhibitors of apoptosis, such as survivin and Bcl-2, is usually increased in atypical cells, which may indicate their involvement in malignant transformation of cells and tumor invasive growth.Conclusion. Our findings confirm the important role of survivin and Bcl-2 in hyperplastic processes in the endometrium.

scholarly journals Neoplasia intraepitelial endometrial: una lesión precursora de cáncer de endometrio

2021 ◽  
Vol 81 (01) ◽  
pp. 75-85
Author(s):  
Ernesto Lara ◽  
Keyword(s):  
Endometrial Cancer ◽  
Endometrial Hyperplasia ◽  
Intraepithelial Neoplasia ◽  
Atypical Hyperplasia ◽  
Classification Systems ◽  
World Health ◽  
Type I ◽  
Female Population ◽  
Typical Sequence ◽  
Endometrial Intraepithelial Neoplasia

Endometrial cancer represents worldwide the sixth most common malignant pathology in the female population, the endometroid type constitutes the most common form, usually developed from a typical sequence of endometrial hyperplasia secondary to sustained exposure to unopposed estrogens balanced by progestogens. Different classification systems for endometrial hyperplasia have been described, the most recent, published by the World Health Organization in 2014, proposes two categories: 1) hyperplasia without atypia, and 2) atypical hyperplasia or endometrial intraepithelial neoplasia. This classification avoids confusion due to the different terms in use and reflects a better understanding of the pathology behavior. Atypical hyperplasia or endometrial intraepithelial neoplasia is considered a precursor lesion to endometrial carcinoma type I. Health professionals must handle standardized terminology, accurately diagnose this entity, and ensure proper treatment of it. Keywords: Endometrial intraepithelial neoplasia, Endometrial hyperplasia, Atypical hyperplasia, Endometrial cancer.

COMPARISON OF ENDOMETRIAL INTRAEPITHELIAL NEOPLASIA & WHO CLASSIFIED ENDOMETRIAL HYPERPLASIA IN PREDICTING THE RISK OF PROGRESSION TO ENDOMETRIAL CARCINOMA

2021 ◽  
pp. 59-61
Author(s):  
Bansi Kavar ◽  
Neeru Dave
Keyword(s):  
Endometrial Cancer ◽  
Endometrial Hyperplasia ◽  
Intraepithelial Neoplasia ◽  
Atypical Hyperplasia ◽  
Cytological Atypia ◽  
Endometrial Intraepithelial Neoplasia ◽  
Risk Of Progression ◽  
Classi Cation ◽  
Cation System ◽  
Sampling Procedures

Background: Endometrial hyperplasia is the precursor lesion of most endometrial cancers of endometrioid type. The most commonly used classication system for endometrial hyperplasia is WHO 1994 classication system in which architecture disruption and cytological atypia are used to identify four types of endometrial hyperplasia including simple or complex hyperplasia with or without atypia. Newer EIN diagnosis by cytological atypia is of great consideration for the progression to endometrial cancer. Material And Methods: The study consists of 100 cases of WHO classied endometrial hyperplasia for period of 4 yrs from 2015 to 2019. Type of sampling procedures- dilation & curettage, endometrial biopsy and fractional curettage. Objective: 1. To discuss revised criteria for recognition of endometrial intraepithelial neoplasia (EIN). 2. To nd out the sensitivity of endometrial intraepithelial neoplasia (EIN) classication in predicting the risk of malignancy. Results: This study consists of 100 cases of endometrial hyperplasia. Patients were mostly postmenopausal & presented with abnormal vaginal bleeding. From WHO classied endometrial lesions, 2 out of 35 cases of simple typical hyperplasia, 10 out of 14 cases of complex typical hyperplasia,12 out of 20 cases of simple atypical hyperplasia and 20 out of 21 cases of complex atypical hyperplasia were reclassied as EI N. Conclusion: To estimate the risk of progression to carcinoma and guide clinical management, the histo-pathologic diagnosis of endometrial hyperplastic lesion is very important, specially the diagnosis of EIN lesions. EIN carries a much greater risk of progression to endometrial cancer than other WHO classied endometrial hyperplasia.

Reassessment of Differentiated Thyroid Cancer Patients Using the Eighth TNM/AJCC Classification System: A Comparative Study

Thyroid ◽  
2018 ◽  
Vol 28 (2) ◽  
pp. 201-209 ◽  
Author(s):  
Miriam Shteinshnaider ◽  
Limor Muallem Kalmovich ◽  
Shlomit Koren ◽  
Karen Or ◽  
Dror Cantrell ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Comparative Study ◽  
Cancer Patients ◽  
Classification System ◽  
Differentiated Thyroid Cancer ◽  
System A
Sign in / Sign up

Export Citation Format

Share Document