Cytokine profiles in 1-yr-old very low-birth-weight infants after enteral glutamine supplementation in the neonatal period

2009 ◽  
Vol 20 (5) ◽  
pp. 467-470 ◽  
Author(s):  
Annelies van Zwol ◽  
Anemone van den Berg ◽  
Edward E. S. Nieuwenhuis ◽  
Jos W. R. Twisk ◽  
Willem P. F. Fetter ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Neonatal Period ◽  
Glutamine Supplementation ◽  
Low Birth Weight Infants ◽  
Cytokine Profiles

Neurodevelopmental outcomes of very low-birth-weight infants after enteral glutamine supplementation in the neonatal period

2008 ◽  
Vol 97 (5) ◽  
pp. 562-567 ◽  
Author(s):  
Annelies van Zwol ◽  
Anemone van den Berg ◽  
Jaap Huisman ◽  
R. Jeroen Vermeulen ◽  
Willem P. Fetter ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Neonatal Period ◽  
Glutamine Supplementation ◽  
Low Birth Weight Infants ◽  
Neurodevelopmental Outcomes

d-Penicillamine and Retinopathy of Prematurity

PEDIATRICS ◽  
1988 ◽  
Vol 82 (6) ◽  
pp. 951-952
Author(s):  
LAJOS LAKATOS
Keyword(s):  
Birth Weight ◽  
Vitamin E ◽  
Low Birth Weight ◽  
Retinopathy Of Prematurity ◽  
Very Low Birth Weight ◽  
Marked Decrease ◽  
Neonatal Period ◽  
Low Birth Weight Infants ◽  
Retrolental Fibroplasia ◽  
Clinical Observations

To the Editor.— The letter to the editor by Johnson et al1 and studies by others regarding vitamin E prophylaxis for retinopathy of prematurity suggest that further research into the prevention of retinopathy of prematurity should not be limited to vitamin E. On the basis of clinical observations we reported that d-penicillamine treatment in the neonatal period was associated with a marked decrease in the incidence of severe retrolental fibroplasia among the very low birth weight infants.2

scholarly journals The repercussions of reduced energy and protein intake during the early neonatal period of very-low-birth-weight infants on their lung function during childhood

2020 ◽  
Author(s):  
José Uberos Fernández ◽  
YOLANDA Gónzalez Jimenez ◽  
Ana Campos-Martínez ◽  
María Tejerizo-Hidalgo ◽  
Elizabeth Fernández-Marín ◽  
...  
Keyword(s):  
Birth Weight ◽  
Lung Function ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Neonatal Period ◽  
Low Birth Weight Infants ◽  
Early Neonatal Period ◽  
Protein Energy ◽  
Z Scores

Background Prematurity and bronchopulmonary dysplasia can modify lung function in children and adults. Postnatal nutrition and rapid growth catch-up may influence the long-term development of lung function. Methods This prospective observational study was based on a cohort of 334 very-low-birth-weight (VLBW) neonates, born between 1 January 2008 and 12 December 2015. Patients with severe neurological damage, death or incomplete data record were excluded. When these infants reached a mean age of 7.7 years, a spirometry evaluation was performed, to determine FEV1, FEF25-75%, FVC and the FEV1/FVC ratio. The relation between these parameters and nutritional intake in the early neonatal period was determined by regression analysis. Results In total, 40 spirometry tests were performed. The results obtained, after adjusting for age and sex by Z-scores for the spirometry variables, showed that the schoolchildren who had been VLBW recorded significantly lower spirometry results (FVC, FEV1, FEF25-75%) than the reference values. Furthermore, there was a significant association between the FEV1/FVC ratio and the intake of macronutrients and energy in the first week of life. It is hypothesised that increasing energy intake and achieving a higher protein/energy ratio in the first week of life would improve the FEV1/FVC ratio by the time these VLBW infants reach school age. Conclusions Active nutritional management in the early neonatal period is associated with improved lung function, as reflected by the spirometry findings obtained.

Early Amplitude-Integrated Electroencephalogram as a Predictor of Brain Injury in Newborns With Very Low Birth Weight: A Cohort Study

2018 ◽  
Vol 33 (10) ◽  
pp. 659-663 ◽  
Author(s):  
Luiza V. S. Magalhães ◽  
Maria Isabel B. Winckler ◽  
José Augusto Bragatti ◽  
Renato S. Procianoy ◽  
Rita C. Silveira
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Neonatal Period ◽  
Positive Likelihood Ratio ◽  
Adverse Outcomes ◽  
Low Birth Weight Infants ◽  
Magnetic Resonance Imaging Mri ◽  
Sensitivity Specificity ◽  
The Relationship

Purpose: To evaluate the relationship between abnormal early amplitude integrated electroencephalography (EEG) and severe lesions in imaging tests performed during the neonatal period in very low birth weight infants. Methods: An amplitude-integrated EEG was performed in 70 patients with a mean birth weight of 1226 g during the first 48 hours of life. Severe lesions on magnetic resonance imaging (MRI) or ultrasonography (US) during the neonatal period were considered as adverse conditions. Variables were compared using the χ2 test or analysis of variance. Sensitivity, specificity, and positive likelihood ratio were calculated. Results: Adverse outcomes were observed in 6 patients. There was a significant relationship ( P < .001) between abnormal amplitude-integrated EEG background and severe lesions on MRI and US. Sensitivity and specificity were 100% and 89%, respectively. Conclusion: Early amplitude-integrated EEG with moderate/severe abnormalities in the background is associated with severe structural lesions detected in imaging studies and should be considered as an auxiliary screening tool for the detection of neonatal brain lesions in very low birth weight infants.

scholarly journals Central diabetes insipidus: alert for dehydration in very low birth weight infants during the neonatal period. A case report

2014 ◽  
Vol 133 (1) ◽  
pp. 60-63 ◽  
Author(s):  
Maria Lúcia Silveira Ferlin ◽  
Débora Simone Sales ◽  
Fábia Pereira Martins Celini ◽  
Carlos Eduardo Martinelli Junior
Keyword(s):  
Case Report ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Diabetes Insipidus ◽  
Very Low Birth Weight ◽  
Neonatal Period ◽  
Central Diabetes Insipidus ◽  
Low Birth Weight Infants ◽  
Normal Fluid ◽  
Fluid Supply

CONTEXT: Central diabetes insipidus (CDI) is a rare cause of hypernatremia during the neonatal period. The diagnosis is particularly difficult in very low birth weight (VLBW) newborns. CASE REPORT: We report on a preterm newborn who presented CDI soon after birth. On the third day of life, signs of dehydration were present despite normal fluid supply. The diuresis rate was 4.4 ml/kg/h. Although the fluid supply was then increased, the dehydration continued, with hypernatremia, normal glycemia, diuresis of 7.4 ml/kg/h and urine density of 1005 mOsmol/l. Thus, a diagnostic hypothesis of diabetes insipidus was raised. A test with a nasal vasopressin analogue (dDAVP) was performed and CDI was confirmed. Reduction of the fluid supply became possible through appropriate treatment. CONCLUSION: The diagnosis of CDI is rarely made during the neonatal period, especially in VLBW newborns, because of the difficulty in detecting elevated diuresis. Persistent hypernatremia, usually accompanied by hyperthermia despite abundant fluid supply, weight loss and low urine osmolality are important signs of alert.

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