Detection of Toxoplasma gondii in Liver Tissue Sections from Brown Hares (Lepus europaeus P.) and Mountain Hares (Lepus timidus L.) using the Peroxidase Anti-Peroxidase (PAP) Technique as a Complement to Conventional Histopathology

1988 ◽  
Vol 35 (1-10) ◽  
pp. 402-407 ◽  
Author(s):  
Katarina Gustafsson ◽  
A. Uggla ◽  
T. Svensson ◽  
L. Sjöland
Keyword(s):  
Toxoplasma Gondii ◽  
Liver Tissue ◽  
Lepus Europaeus ◽  
Lepus Timidus ◽  
Tissue Sections

Crisp and soft multivariate methods visualize individual cell nuclei in Raman images of liver tissue sections

2011 ◽  
Vol 55 (1) ◽  
pp. 90-100 ◽  
Author(s):  
Christoph Krafft ◽  
Mehrnaz Alipour Diderhoshan ◽  
Peter Recknagel ◽  
Milos Miljkovic ◽  
Michael Bauer ◽  
...  
Keyword(s):  
Liver Tissue ◽  
Individual Cell ◽  
Multivariate Methods ◽  
Cell Nuclei ◽  
Tissue Sections

scholarly journals THE EFFECT OF PRETREATMENT WITH TOLL-LIKE RECEPTOR 4 ANTAGONIST RESATORVID ON METHOTREXATE-INDUCED LIVER INJURY IN RATS: HISTOPATHOLOGICAL STUDY

2018 ◽  
Vol 11 (12) ◽  
pp. 560
Author(s):  
Bassim I Mohammad ◽  
Bassim S Ahmed ◽  
Alaa F Hassan ◽  
Samer F Hassan
Keyword(s):  
Liver Tissue ◽  
Inflammatory Cells ◽  
Fatty Degeneration ◽  
Treated Group ◽  
Control Group ◽  
Histopathological Study ◽  
Tissue Samples ◽  
Alcoholic Fatty Liver ◽  
Tissue Sections ◽  
Microscopic Evaluation

Objective: This research aims to evaluate the histopathological changes after pretreatment with resatorvid against methotrexate induced-liver injury.Methods: 28 male albino-wistar rats divided into random 4 groups (7 rats in each). Control group: Rats left untreated. Vehicle pre-treated group: Rats were administered dimethyl sulfoxide (DMSO) followed by methotrexate (MTX). Methotrexate treated group: Rats left untreated then administered MTX. Resatorvid pre-treated group: Rats were administered resatorvid followed by MTX. 24 h after the end of treatment, the animals were sacrificed. Liver tissue samples dissected out immediately and fixed in 10% formalin. The traditional procedures (paraffin-embedded method) was used to prepare liver tissue for microscopic evaluation by none alcoholic fatty liver disease (NAFLD) Activity Score Components.Results: Liver tissue sections of MTX-treated group show moderate-to-severe steatosis of hepatic cells and micro- and macro- hepatocellular fatty degeneration and giant fatty cysts with chronic inflammatory cells infiltration. While liver tissue sections of the resatorvid pre-treated group show moderate hepatic cellular fatty degeneration, with a decreased number of fatty cysts chains and the inflammation disappeared.Conclusion: Resatorvid hepatoprotective effect against MTX-induced injury was promising throughout resolving the accompanying inflammation and partial restoring histopathological fatty alterations.

Sign in / Sign up

Export Citation Format

Share Document