scholarly journals Migraine and obesity: epidemiology, possible mechanisms and the potential role of weight loss treatment

2010 ◽  
Vol 12 (5) ◽  
pp. e362-e371 ◽  
Author(s):  
D. S. Bond ◽  
J. Roth ◽  
J. M. Nash ◽  
R. R. Wing
Keyword(s):  
Weight Loss ◽  
Potential Role ◽  
Weight Loss Treatment

Fat-Free Mass Changes During Ketogenic Diets and the Potential Role of Resistance Training

2016 ◽  
Vol 26 (1) ◽  
pp. 78-92 ◽  
Author(s):  
Grant M. Tinsley ◽  
Darryn S. Willoughby
Keyword(s):  
Weight Loss ◽  
Resistance Training ◽  
Ketogenic Diet ◽  
Potential Role ◽  
Mass Measurement ◽  
Fat Free Mass ◽  
Exercise Interventions ◽  
Ketogenic Diets ◽  
Low Carbohydrate

Low-carbohydrate and very-low-carbohydrate diets are often used as weight-loss strategies by exercising individuals and athletes. Very-low-carbohydrate diets can lead to a state of ketosis, in which the concentration of blood ketones (acetoacetate, 3-β-hydroxybutyrate, and acetone) increases as a result of increased fatty acid breakdown and activity of ketogenic enzymes. A potential concern of these ketogenic diets, as with other weight-loss diets, is the potential loss of fat-free mass (e.g., skeletal muscle). On examination of the literature, the majority of studies report decreases in fat-free mass in individuals following a ketogenic diet. However, some confounding factors exist, such as the use of aggressive weight-loss diets and potential concerns with fat-free mass measurement. A limited number of studies have examined combining resistance training with ketogenic diets, and further research is needed to determine whether resistance training can effectively slow or stop the loss of fat-free mass typically seen in individuals following a ketogenic diet. Mechanisms underlying the effects of a ketogenic diet on fat-free mass and the results of implementing exercise interventions in combination with this diet should also be examined.

scholarly journals Impact of Resected Gastric Volume on Postoperative Weight Loss after Laparoscopic Sleeve Gastrectomy

2019 ◽  
Vol 2019 ◽  
pp. 1-5 ◽  
Author(s):  
Stefano D’Ugo ◽  
Vittoria Bellato ◽  
Emanuela Bianciardi ◽  
Paolo Gentileschi
Keyword(s):  
Weight Loss ◽  
Sleeve Gastrectomy ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Potential Role ◽  
Gastric Volume ◽  
Specimen Size ◽  
Postoperative Weight Loss ◽  
The Mean

Among the bariatric surgery community, it has recently emerged the idea of a possible association between resected gastric volume (RGV) and weight loss after laparoscopic sleeve gastrectomy (LSG). If the size of the sleeve depends on the bougie caliber, the resected volume of the stomach remains something which is not possible to standardize. The aim of the study was to investigate a possible relationship between RGV and weight loss after LSG. We developed a mathematical method to calculate the RGV, based on the specimen size removed during LSG. Ninety-one patients (63 females and 28 males) affected by morbid obesity were included in the study. They underwent LSG between 2014 and 2016. Mean preoperative BMI was 45±6.4. At 1 year after LSG, the mean BMI was 30±5.3 and the EWL% was 65±20.2. The statistical analysis of RGV, BMI, and EWL% at 1-year follow-up did not find any correlation between the volume of stomach removed and the weight loss after LSG. Further studies in the future should clarify the potential role of RGV during LSG. This trial is registered with ClinicalTrials.gov NCT03938025.

scholarly journals Is activation of human brown adipose tissue a viable target for weight management?

2018 ◽  
Vol 315 (3) ◽  
pp. R479-R483 ◽  
Author(s):  
Kara L. Marlatt ◽  
Kong Y. Chen ◽  
Eric Ravussin
Keyword(s):  
Weight Loss ◽  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Weight Control ◽  
Potential Role ◽  
Metabolic Adaptation ◽  
Weight Changes ◽  
Brown Adipose ◽  
Pharmacological Studies

To date, human studies show that brown adipose tissue (BAT) contributes a small yet highly variable amount to overall energy expenditure. No studies have shown a decrease in body weight with cold-induced BAT activation, and existing pharmacological studies suggest that BAT activation via the sympathetic nervous system may result in increased heart rate and systolic blood pressure. Furthermore, even though the amount and/or activity of BAT have been shown to vary with seasons, such variation does not seem to be translated into weight changes. Collectively, these findings do not support the use of BAT activation for weight loss in humans; however, the potential role of BAT in counteracting the metabolic adaptation observed with weight loss is suggested. Although the role of BAT in weight control is currently unsubstantiated, BAT may play a role in improving insulin sensitivity in humans.

Potential role of meal frequency as a strategy for weight loss and health in overweight or obese adults

Nutrition ◽  
2014 ◽  
Vol 30 (4) ◽  
pp. 386-392 ◽  
Author(s):  
Michelle G. Kulovitz ◽  
Len R. Kravitz ◽  
Christine Mermier ◽  
Ann L. Gibson ◽  
Carole A. Conn ◽  
...  
Keyword(s):  
Weight Loss ◽  
Potential Role ◽  
Meal Frequency ◽  
Obese Adults

Weight Loss-Induced Calciphylaxis: Potential Role of Matrix Metalloproteinases

2003 ◽  
Vol 30 (12) ◽  
pp. 915-919 ◽  
Author(s):  
Girish Munavalli ◽  
Amy Reisenauer ◽  
Marsha Moses ◽  
Susan Kilroy ◽  
Jack L. Arbiser
Keyword(s):  
Weight Loss ◽  
Matrix Metalloproteinases ◽  
Potential Role

POPDC proteins and cardiac function

2019 ◽  
Vol 47 (5) ◽  
pp. 1393-1404 ◽  
Author(s):  
Thomas Brand
Keyword(s):  
Potential Role ◽  
Striated Muscle ◽  
Short Review ◽  
Effector Proteins ◽  
Muscle Disease ◽  
Disease Genes ◽  
Protein Protein Interaction ◽  
Interaction Partners ◽  
And Function

Abstract The Popeye domain-containing gene family encodes a novel class of cAMP effector proteins in striated muscle tissue. In this short review, we first introduce the protein family and discuss their structure and function with an emphasis on their role in cyclic AMP signalling. Another focus of this review is the recently discovered role of POPDC genes as striated muscle disease genes, which have been associated with cardiac arrhythmia and muscular dystrophy. The pathological phenotypes observed in patients will be compared with phenotypes present in null and knockin mutations in zebrafish and mouse. A number of protein–protein interaction partners have been discovered and the potential role of POPDC proteins to control the subcellular localization and function of these interacting proteins will be discussed. Finally, we outline several areas, where research is urgently needed.

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