Glycosignaling in neural stem cells: involvement of glycoconjugates in signal transduction modulating the neural stem cell fate

2007 ◽  
Vol 103 (s1) ◽  
pp. 39-46 ◽  
Author(s):  
Robert K. Yu ◽  
Makoto Yanagisawa
Keyword(s):  
Signal Transduction ◽  
Stem Cells ◽  
Stem Cell ◽  
Neural Stem Cells ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
Stem Cell Fate

The neural stem cell fate determinant TLX promotes tumorigenesis and genesis of cells resembling glioma stem cells

2010 ◽  
Vol 30 (5) ◽  
pp. 403-408 ◽  
Author(s):  
Hyo-Jung Park ◽  
Jun-Kyum Kim ◽  
Hye-Min Jeon ◽  
Se-Yeong Oh ◽  
Sung-Hak Kim ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
Glioma Stem Cells ◽  
Stem Cell Fate ◽  
Cell Fate Determinant

scholarly journals Erratum to: The Neural Stem Cell Fate Determinant TLX Promotes Tumorigenesis and Genesis of Cells Resembling Glioma Stem Cells

2011 ◽  
Vol 31 (2) ◽  
pp. 199-199 ◽  
Author(s):  
Hyo-Jung Park ◽  
Jun-Kyum Kim ◽  
Hye-Min Jeon ◽  
Se-Yeong Oh ◽  
Sung-Hak Kim ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
Glioma Stem Cells ◽  
Stem Cell Fate ◽  
Cell Fate Determinant

Stem cell fate: extracellular glutamine shock for identification of key metabolic influencers in pluripotent and neural stem cells

2018 ◽  
Vol 44 ◽  
pp. S87
Author(s):  
J. Vasconcelos E Sá ◽  
D. Simão ◽  
M.M. Silva ◽  
A.P. Terrasso ◽  
I.A. Isidro ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Neural Stem Cells ◽  
Cell Fate ◽  
Stem Cell Fate

scholarly journals BASP1 labels neural stem cells in the neurogenic niches of mammalian brain

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Louis N. Manganas ◽  
Irene Durá ◽  
Sivan Osenberg ◽  
Faith Semerci ◽  
Mehmet Tosun ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Stem Cells ◽  
Stem Cell ◽  
Western Blot ◽  
Human Brain ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
Developmental Stages ◽  
Mammalian Brain ◽  
Stem Cell Fate

AbstractThe mechanisms responsible for determining neural stem cell fate are numerous and complex. To begin to identify the specific components involved in these processes, we generated several mouse neural stem cell (NSC) antibodies against cultured mouse embryonic neurospheres. Our immunohistochemical data showed that the NSC-6 antibody recognized NSCs in the developing and postnatal murine brains as well as in human brain organoids. Mass spectrometry revealed the identity of the NSC-6 epitope as brain abundant, membrane-attached signal protein 1 (BASP1), a signaling protein that plays a key role in neurite outgrowth and plasticity. Western blot analysis using the NSC-6 antibody demonstrated multiple BASP1 isoforms with varying degrees of expression and correlating with distinct developmental stages. Herein, we describe the expression of BASP1 in NSCs in the developing and postnatal mammalian brains and human brain organoids, and demonstrate that the NSC-6 antibody may be a useful marker of these cells.

scholarly journals Drosophila as a Model for Developmental Biology: Stem Cell-Fate Decisions in the Developing Nervous System

2018 ◽  
Vol 6 (4) ◽  
pp. 25 ◽  
Author(s):  
Katherine Harding ◽  
Kristin White
Keyword(s):  
Stem Cells ◽  
Nervous System ◽  
Stem Cell ◽  
Neural Stem Cells ◽  
Cell Fate ◽  
Cell Behavior ◽  
Stem Cell Fate ◽  
Cell Fate Decisions ◽  
Unique System ◽  
Developing Nervous System

Stem cells face a diversity of choices throughout their lives. At specific times, they may decide to initiate cell division, terminal differentiation, or apoptosis, or they may enter a quiescent non-proliferative state. Neural stem cells in the Drosophila central nervous system do all of these, at stereotypical times and anatomical positions during development. Distinct populations of neural stem cells offer a unique system to investigate the regulation of a particular stem cell behavior, while comparisons between populations can lead us to a broader understanding of stem cell identity. Drosophila is a well-described and genetically tractable model for studying fundamental stem cell behavior and the mechanisms that underlie cell-fate decisions. This review will focus on recent advances in our understanding of the factors that contribute to distinct stem cell-fate decisions within the context of the Drosophila nervous system.

Human Mesenchymal Stem Cells Signals Regulate Neural Stem Cell Fate

2006 ◽  
Vol 32 (2) ◽  
pp. 353-362 ◽  
Author(s):  
Lianhua Bai ◽  
Arnold Caplan ◽  
Donald Lennon ◽  
Robert H. Miller
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
Human Mesenchymal Stem Cells ◽  
Stem Cell Fate

Instructions from the Vascular System - Directing Neural Stem Cell Fate in Health and Disease

2014 ◽  
Vol 21 (19) ◽  
pp. 2190-2207 ◽  
Author(s):  
S. Schildge ◽  
C. Bohrer ◽  
S. Pfurr ◽  
K. Mammadzada ◽  
K. Schachtrup ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
Vascular System ◽  
Stem Cell Fate ◽  
Health And Disease
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