Use of a high molecular weight fluorescein (fluorexon) ophthalmic strip in assessments of tear film break-up time in contact lens wearers and non-contact lens wearers

2005 ◽  
Vol 25 (2) ◽  
pp. 119-127 ◽  
Author(s):  
Michael J. Doughty ◽  
Vinati Jalota ◽  
Emma Bennett ◽  
Taher Naase ◽  
Emil Oblak
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Contact Lens ◽  
Tear Film ◽  
Break Up

Managing Corneal Epithelial Defects Using High Molecular Weight Fluorescein to Prevent Contact Lens Staining and Removal of Bandage Contact Lenses

2020 ◽  
Vol 3 (8) ◽  
pp. 20-22
Author(s):  
Muhammad Hamza ◽  
Chrishan Gunasekera ◽  
Samar Nahas ◽  
Z CX Lin ◽  
Hatch Mukherjee ◽  
...  
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Contact Lens ◽  
Contact Lenses ◽  
Corneal Epithelial

scholarly journals DRY EYE STATUS BASED ON THE SCHIRMER TEST AND TEAR FILM BREAK UP TIME RESULTS FOLLOWING USE OF SOFT CONTACT LENS IN KERALA

2019 ◽  
Vol 3 (10) ◽  
Author(s):  
Dr. Simon George
Keyword(s):  
Dry Eye ◽  
Contact Lens ◽  
Tear Film ◽  
Test Results ◽  
Schirmer Test ◽  
Soft Contact ◽  
Soft Contact Lens ◽  
Break Up

Prospective two years study of the dry eye status following use of soft contact lens. Based on the Schirmer test results, 10 % soft contact lens wearers developed mild dry eye at the end of 1 year and 15 % developed mild dry eye at the end of 2 years. No patient had moderate or severe dry eye. Based on the Tear film break up time results, 17 % soft contact lens wearers developed mild dry eye at the end of 1 year and 30 % developed mild dry eye at the end of 2 years. 1% had moderate dry eye at the end of 2 years. No patient had severe dry eye. Keywords: Schirmer test, Tear film break up time, soft contact lens, dry eye

Effect of Contact Lens Wear and a Near Task on Tear Film Break-Up

2010 ◽  
pp. 1 ◽  
Author(s):  
Meredith E. Jansen ◽  
Carolyn G. Begley ◽  
Nikole H. Himebaugh ◽  
Nicholas L. Port
Keyword(s):  
Contact Lens ◽  
Tear Film ◽  
Contact Lens Wear ◽  
Break Up ◽  
Lens Wear

scholarly journals Effect of Soft Contact Lens Wear on Tear Film Break up Time

2020 ◽  
Vol 36 (2) ◽  
Author(s):  
Syeda Rushda Zaidi ◽  
Mohammad Ali A Sadiq ◽  
Shua Azam ◽  
Uzma Sattar ◽  
Samia Iqbal ◽  
...  
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Tear Film ◽  
Soft Contact ◽  
Contact Lens Wear ◽  
Soft Contact Lens ◽  
History Of ◽  
Break Up ◽  
Medical University ◽  
Lens Wear

Purpose:  To see the effect of soft contact lens wears on tear breakup time. Study Design:  Descriptive Observational study. Place and Duration of Study:  College of Ophthalmology and Allied Vision Sciences, King Edward Medical University, Mayo Hospital, Lahore. From January to March 2016. Material and Methods:  Students of King Edward Medical University Lahore wearing soft contact lens for more than 3 months with no  known ocular pathology were selected by non-probability convenient sampling technique. Subjects with history of using any eye drops, history of oral drugs, which could cause dry eye and individuals any ocular disease, were excluded from the study. Tear film BUT was tested by using Fluorescein sodium dye and examinig under cobalt blue filter of slit lamp.SPSS version 20 is used to analyze the data. Results:  There were 30 participants with mean age of 24.5 ± 5 years. All were females. Sixty percent were wearing corrective lenses, and 40% were wearing cosmetic lenses. Out of 30 patients wearing contact lenses, only 6.67% had marginal tear film BUT and none of the patients has shown dry eyes. Individuals using contact lenses for 9 – 12 years had decreased BUT as compared to subjects using lenses for 3 – 6 months. 33.33% of extended lens wearers had reduced BUT as compared to disposable and daily wearers of contact lenses. Discomfort with contact lenses was observed in only 4 patients. Conclusion:  As the duration of contact lens wear increases, the tear film break up time decreases. Individuals using extended wear contact lenses are more prone to develop decreased TFBUT.

scholarly journals The HYLAN M Study: Efficacy of 0.15% High Molecular Weight Hyaluronan Fluid in the Treatment of Severe Dry Eye Disease in a Multicenter Randomized Trial

2020 ◽  
Vol 9 (11) ◽  
pp. 3536 ◽  
Author(s):  
Gysbert-Botho van Setten ◽  
Christophe Baudouin ◽  
Jutta Horwath-Winter ◽  
Daniel Böhringer ◽  
Oliver Stachs ◽  
...  
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Dry Eye ◽  
Tear Film ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Control Group ◽  
Eye Drops ◽  
Artificial Tears ◽  
Ocular Surface Disease Index

The aim of the HYLAN M study was to investigate if symptoms and/or signs of patients suffering from severe dry eye disease (DED) can be improved by substituting individually optimized artificial tear therapy by high molecular weight hyaluronan (HMWHA) eye drops. In this international, multicenter study, patients with symptoms of at least ocular surface disease index (OSDI) 33 and corneal fluorescein staining (CFS) of at least Oxford grade 3 were included. A total of 84 per-protocol patients were randomized in two study arms. The control group continued to use their individual optimum artificial tears over the study period of eight weeks; in the verum group, the artificial tears were substituted by eye drops containing 0.15% HMWHA. At the week 8 visit, the average OSDI of the verum group had improved by 13.5 as compared to the control group (p = 0.001). The best corrected visual acuity (BCVA) had improved by 0.04 logMAR (p = 0.033). CFS, tear film break-up time (TBUT), Schirmer I, lid wiper epitheliopathy (LWE), mucocutaneous junction (Yamaguchi score), and tear osmolarity were not significantly different between the verum and control groups (p > 0.050). We conclude that for most patients with severe DED, 0.15% HMWHA eye drops provide excellent improvement of symptoms without impairment of dry eye signs.

scholarly journals Tear Film Evaluation in Contact Lens Wearers and Non Wearers

2013 ◽  
Vol 34 (2) ◽  
pp. 14-20
Author(s):  
GS Shrestha ◽  
D Sujakhu ◽  
JB Shrestha ◽  
JK Shrestha
Keyword(s):  
Dry Eye ◽  
Contact Lens ◽  
Tear Film ◽  
Subjective Assessment ◽  
Institute Of Medicine ◽  
Non Invasive ◽  
Function Tests ◽  
Eye Symptoms ◽  
Break Up ◽  
Dry Eye Symptoms

Background: Dry eye symptoms are more frequent in contact lens wearers than in non wearers. Dry eye is considered relatively common in contact lens wearers than non-wearers. However, there was no any report in our clinical setting that compared and addressed the issue related to dry eye and its symptom in contact lens wearers. The present study was conducted to compare pre-ocular tear lm in contact lens wearers (CLW) and contact lens non wearers (CLNW), and evaluate the relationship between clinical and subjective assessment of dry eye symptoms. Methods: It was a comparative study conducted among 131 subjects (262 eyes) attended in the contact lens clinic at BP Koirala Lions Center for the Ophthalmic Studies. Sixty five were daily soft contact lens wearers; sixty-six were non wearers. Tear function assessment included non- invasive tear break up time, invasive tear break up time, tear prism height and Schirmer II test. Subjective assessment of dry eye symptoms was carried out using McMonnies questionnaires. Results: Mean age of CLNW was 23.01± 5.53 and CLW was 23.6± 4.61. Female (89 subjects) visited more than male (42 subjects) in contact lens clinic. Mean symptom score in CLW was significantly higher than CLNW (p<0.001). But, distribution of symptomatology was not significantly different in both groups. Symptomatic subjects were elder (p<0.001) and female (p<0.05) in CLNW and only elder subjects in CLW. Tear function tests were significantly lower in symptomatic subjects in CLW and CLNW; Overall tear function test scores were also lower in CLW than CLNW. Tear function tests scores were insignificantly different in male and female. Coefficient of correlation was positive and weak for all tear function tests scores. Conclusions: Though, tear function tests scores were reduced in CLW than CLNW, dry eye symptomatology was almost similar. Subjective assessment of symptoms is as important as clinical tests. DOI: http://dx.doi.org/10.3126/joim.v34i2.9044 Journal of Institute of Medicine August, 2012; 34:2 14-20

PURIFICATION AND CHEMICAL CHARACTERISATION OF THE HIGH MOLECULAR WEIGHT GLYCOCONJUGATE FRACTION OF THE BOVINE TEAR FILM AND COMPARISON TO HUMAN TEARS.

Cornea ◽  
2000 ◽  
Vol 19 (Supplement 2) ◽  
pp. S74
Author(s):  
Malcolm S Ball ◽  
Katherine N Hollis-Watts ◽  
Niclas Karlsson ◽  
Nicolle Packer ◽  
Mark DP Willcox
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Tear Film
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