Managing Corneal Epithelial Defects Using High Molecular Weight Fluorescein to Prevent Contact Lens Staining and Removal of Bandage Contact Lenses

2020 ◽  
Vol 3 (8) ◽  
pp. 20-22
Author(s):  
Muhammad Hamza ◽  
Chrishan Gunasekera ◽  
Samar Nahas ◽  
Z CX Lin ◽  
Hatch Mukherjee ◽  
...  
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Contact Lens ◽  
Contact Lenses ◽  
Corneal Epithelial

scholarly journals Could contact lens dryness discomfort symptoms sometimes have a neuropathic basis?

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Charles W. McMonnies
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Front Surface ◽  
Negative Influence ◽  
Ambient Conditions ◽  
Corneal Epithelial ◽  
Soft Contact Lens ◽  
Cellular Debris ◽  
History Of

AbstractSymptoms of dryness discomfort in soft contact lens wearers frequently lead to discontinuation from wear. The negative influence of pre-fitting tear dysfunctions appears likely to be exacerbated by the challenges to tear homeostasis caused by contact lenses. The corneal mechanisms for symptoms in contact lens wearers are different to those for dry eye disease because the cornea is insulated by the lens from ambient conditions as well as from lid wiper friction during blinking. Symptoms of dryness discomfort might be the consequence of increased lid wiper friction during blinking when the lens front surface becomes soiled and dry and exhibits very rapid tear break up. It is possible that some cases of contact lens intolerance and discontinuation could be a function of lid wiper neuropathy. In relation to the possibility of corneal neuropathy, a stagnant post-lens tear pool with the possibility of increased concentrations of metabolic by-products, cellular debris, and bacterial exotoxins, might have the potential to disturb the corneal epithelial and sub-basal nerves. Contributions by contact lens-induced inflammation to any neuropathic changes may partly depend on the degree to which inflammatory mediators are concentrated in a stagnant post-lens tear pool. It does not appear to be known if corneal neuropathic changes could develop under these conditions. The chances of neuropathic involvement may be greater if discomfort develops after a significant period of successful wear and there is a history of comorbid pain conditions. Esthesiometry and in vivo confocal microscopy in discontinued contact lens wearers may support a diagnosis of contact lens-related corneal neuralgia.

scholarly journals EVALUATION OF CLINICAL AND FUNCTIONAL OUTCOME OF MULTIFOCAL CORRECTION BY CONTACT LENS IN PATIENTS WITH PRESBYOPIA AND MYOPIA REFRACTION

2016 ◽  
Vol 1 (6) ◽  
pp. 103-107
Author(s):  
Рогожникова ◽  
Elena Rogozhnikova ◽  
Селиверстова ◽  
Nataliya Seliverstova ◽  
Розанова ◽  
...  
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Tear Film ◽  
Functional Results ◽  
Corneal Epithelial ◽  
Interaction Field ◽  
Standard Procedures ◽  
Quality Of Vision ◽  
Selection Of

The aim of the study was to evaluate the effectiveness of multifocal contact lens correction in patients with presbyopia and myopic refractive error. The study involved 45patients with myopia ranging in age from 43 to 56years in conditions of habitual monofocal contact lens correction, a month after the selection and wearing multifocal contact lenses. Contact correction was carried out according to standard procedures taking into account the accuracy of contact lens fitting, with carrying out functional tests for the “dry eye” syndrome and evaluation of corneal epithelial thickness (Optovue, USA). The as-sessment of the following parameters of visual perception was made: far, near and middle distance (monocular and binocular) visual acuity, the spatial contrast sensitivity, stereovision (I & II Lang test), the area of binocular interaction field (binarymeter), the quality of vision (VF-14 test ). The use of multifocal contact lenses for the correction of presbyopia with the initial myopic refraction ensures high functional results at different distances. Patients with a myopic refraction, previously used contact lenses, easy pass to multifocal correction option. The greatest satisfaction by achieved vision noted in those patients who had achieved refraction (–)0.5diopters. In the selection of contact lenses in older patients the thickness of the corneal epithelium and tear film validity must be taken into account.

scholarly journals Infectious Keratitis Associated with Contact Lenses

2021 ◽  
Vol 20 (4) ◽  
pp. 140-143
Author(s):  
Kyong Jin Cho
Keyword(s):  
Patient Education ◽  
Contact Lens ◽  
Contact Lenses ◽  
Infectious Keratitis ◽  
Corneal Surface ◽  
Corneal Epithelial Cells ◽  
Myopia Progression ◽  
Corneal Epithelial ◽  
Corneal Infection ◽  
Tear Flow

The use of contact lenses for correcting refraction, suppressing myopia progression, and cosmetic purposes is increasing steadily. Contact lenses have various effects on the corneal surface and corneal infection can occur following obstruction of tear flow, micro-damage to corneal epithelial cells, corneal hypoxia, changes in corneal immunity, and exposure to contaminants. When a patient who used to wear contact lenses presents with keratitis, it is important to distinguish whether it is an infection; if it is an infection, it is important to find the causative strain and promptly treat it appropriately. Since improper lens care is related to infection, appropriate patient education is necessary, and the risk of contact lens infection should be reduced through regular ophthalmic examinations.

scholarly journals Life on contact lenses: Exploiting a modern habitat

2009 ◽  
Vol 31 (4) ◽  
pp. 26-27
Author(s):  
James Lonnen
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Risk Of Infection ◽  
Microbial Keratitis ◽  
Corneal Epithelial ◽  
Contact Lens Wear ◽  
The World ◽  
Micro Organisms ◽  
And Storage ◽  
Lens Wear

There are an estimated 125 million contact lens wearers across the world, and the majority experience few complications; however, it is well known that contact lens wear is a risk factor for microbial keratitis (infection of the cornea of the eye). Owing to the ubiquitous distribution of micro-organisms, it is extremely di cult to prevent them from colonizing contact lens storage cases. Bacteria, fungi and protozoa have all been found in contact lens storage cases; these micro-organisms can adhere to the contact lens, which then acts as a vector to transport the microbes on to the surface of the eye. Bacteria such as Pseudomonas aeruginosa, fungi such as Fusarium solani and the protazoan parasite Acanthamoeba–to name but a few–can cause infection of the corneal epithelial cells, which, if untreated, can lead to blindness. It is therefore essential that wearers clean and disinfect their contact lenses and storage cases e ectively to minimize the risk of infection.

scholarly journals Visual Outcomes with Contact Lenses Previous Keratoplasty

2012 ◽  
Vol 1 (3) ◽  
pp. 196-200
Author(s):  
Gonzalo Carracedo
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Low Vision ◽  
Corneal Epithelial ◽  
Visual Outcomes ◽  
Quality Of Vision ◽  
The Right ◽  
Interim Period

ABSTRACT We describe a case of a 22-year-old patient, with severe keratoconus in both eyes. Penetrating keratoplasty in left eye was performed in August 2011. The patient was awaiting postoperative stabilization of this eye prior to surgery on the right eye. Therefore, a Clearkone® hybrid contact lens was fitted on the right eye to maintain corneal epithelial integrity, improve quality of vision and therefore qualify of life during this interim period. Visual acuity with the contact lens was +0.1 logMAR. Comfort was excellent and the patient was able to wear the Clearkone® lens up to 12 hours per day. Similar outcomes regarding vision and comfort were obtained at follow-up visits through 9 months. In conclusion, new hybrid contact lens designs for keratoconus are an excellent option for vision rehabilitation in severe cases of keratoconus which would otherwise be left with low vision for several months while waiting for keratoplasty. How to cite this article Carracedo G. Visual Outcomes with Contact Lenses Previous Keratoplasty. Int J Kerat Ect Cor Dis 2012;1(3):196-200.

Microtubule motors and other maps

1990 ◽  
Vol 48 (3) ◽  
pp. 1-1
Author(s):  
Richard B. Vallee
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Cytoplasmic Dynein ◽  
Organelle Transport ◽  
Structural Components ◽  
Microtubule Associated Proteins ◽  
Microtubule Motors ◽  
Associated Proteins ◽  
The Subject ◽  
Intracellular Motility

Microtubules are involved in a number of forms of intracellular motility, including mitosis and bidirectional organelle transport. Purified microtubules from brain and other sources contain tubulin and a diversity of microtubule associated proteins (MAPs). Some of the high molecular weight MAPs - MAP 1A, 1B, 2A, and 2B - are long, fibrous molecules that serve as structural components of the cytamatrix. Three MAPs have recently been identified that show microtubule activated ATPase activity and produce force in association with microtubules. These proteins - kinesin, cytoplasmic dynein, and dynamin - are referred to as cytoplasmic motors. The latter two will be the subject of this talk.Cytoplasmic dynein was first identified as one of the high molecular weight brain MAPs, MAP 1C. It was determined to be structurally equivalent to ciliary and flagellar dynein, and to produce force toward the minus ends of microtubules, opposite to kinesin.

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